Results 41 to 50 of about 857,317 (238)

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

Molecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi, Jérome Vialaret, Christophe Hirtz, Catherine Alix‐Panabières   +3 more
wiley   +1 more source

Mushrooms as a Source of Anti-Inflammatory Agents

Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry, 2010
Inflammation is nowadays well known to be involved in the development of several chronic diseases such as arteriosclerosis, obesity, diabetes, neurodegenerative diseases, and cancer. Treatment for chronic inflammatory disorders has not been solved yet, and there is an urgent need to find new and safe anti-inflammatory preventive and therapeutic ...
García - Lafuente, A., Moro, C., Villares Garicochea, Ana, Guillamon, E., Rostagno, M. A., d'Arrigo, M., Martinez, J. A.   +6 more
openaire   +7 more sources

Multifunctional Silver-based Nanomaterials for Non-conventional Oral Cancer Therapy through Simultaneous LOX and Selective COX-2 inhibition [PDF]

, 2022
Neoplastic cells have co-opted inflammatory receptors and signaling molecules that potentiate inflammation. Activated inflammatory pathways lead to neo-angiogenesis, lymph-angiogenesis, immunosuppression, tumor growth, proliferation and metastasis.
Baino F., Dar M. J., Malik A., Munir S., Naz S. S., Qaisar S., Qindeel M., Rahdar A., Razlansari M., Shah K. U., Ur Rehman F., Wahid F.   +11 more
core  

Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors – a biomarker analysis of the ALICE and ICON trials

Molecular Oncology, EarlyView.
In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Elin Borgen, Cecilie Bendigtsen Schirmer, Bjørnar Gilje, Øystein Garred, Jon Lømo, Marius Stensland, Oddmund Nordgård, Ragnhild Sørum Falk, Randi R. Mathiesen, Hege G. Russnes, Jon Amund Kyte, Bjørn Naume   +13 more
wiley   +1 more source

Neuroprotection: The Way of Anti-Inflammatory Agents [PDF]

, 2020
Neurons are basic structural and functional units of the nervous system with major function being that of integration and interpretation of neuronal input or information.
Donkeng, Martial Boris, Nzogang, Patrice Mendel   +1 more
core   +1 more source

Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients

Molecular Oncology, EarlyView.
Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha, Steven Kao, Veronica K. Cheung, Wendy A. Cooper, Nico van Zandwijk, John E. J. Rasko, Dannel Yeo   +6 more
wiley   +1 more source

Study of evaluation of anti-inflammatory activity of macrolide antibiotics in rats: an experimental study [PDF]

, 2016
Background: Inflammation is a complex and dynamic condition in which many changes take place at the site of inflammation, as well as systemically. In general, inflammatory response acts to protect the host, but many times it goes unchecked with tissue ...
Dharmadhikari, Shrikant C., Gosavi, Punam A., Jaju, Jugalkishore B., Pawar, Ganesh R., Ubale, Vishal M.   +4 more
core   +2 more sources

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

Molecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić, Florian Lüke, Steffi Treitschke, Andrea Coluccio, Martin Hoffmann, Giancarlo Feliciello, Adithi Ravikumar Varadarajan, Xin Lu, Kathrin Weidele, Catherine Botteron, Silvia Materna–Reichelt, Felix Keil, Katja Evert, Florian Weber, Thomas Schamberger, Michael Althammer, Jirka Grosse, Dirk Hellwig, Christian Schulz, Stephan Seitz, Peter Ugocsai, Anke Schlenska‐Lange, Roman Mayr, Ulrich Kaiser, Wolfgang Dietmaier, Bernhard Polzer, Jens Warfsmann, Kamran Honarnejad, Tobias Pukrop, Daniel Heudobler, Christoph A. Klein, Christian Werno   +31 more
wiley   +1 more source

Lyprinol—Is It a Useful Anti‐Inflammatory Agent? [PDF]

Evidence-Based Complementary and Alternative Medicine, 2011
The New Zealand green lipped mussel preparation Lyprinol is available without a prescription from a supermarket, pharmacy or Web. The Food and Drug Administration have recently warned Lyprinol USA about their extravagant anti‐inflammatory claims for Lyprinol appearing on the web. These claims are put to thorough review.
openaire   +4 more sources

Medicinal Plants and Natural Compounds in the Treatment of Acne: A Review [PDF]

, 2018
Introduction: Acne is an infectious chronic inflammatory disorder occurring in skin's outer tissue and characterized by seborrhea, pimples, papules, comedowns and nodules based on severity. It can be caused by increased sebum production, abnormalities in
Amir Sardari, Romina, Goudarzian, Taraneh, Hosseinabadi, Tahereh, Mehryab, Fatemeh, Solouti, Maryam   +4 more
core   +2 more sources