Results 41 to 50 of about 993,667 (346)

Choosing and using non-steroidal anti-inflammatory drugs in haemophilia [PDF]

, 2016
The management of pain and inflammation in haemophilic arthropathy is challenging due to the lack of anti-inflammatory analgesic agents perfectly suitable for this population.
Baigent, Biere-Rafi, Braden, Brown, Button, Cagnoni, Caldwell, Castellsague, Chen, Crofford, Curhan, Daly, de Abajo, Dolan, Dworzynski, Eyster, FitzGerald, Forbes, Forman, Fransen van de Putte, Garcia-Poza, Gisbert, Gonzalez-Perez, Grosser, Hallas, Harirforoosh, Hawkey, Hinz, Holstein, Huerta, Hunt, Hunt, Huntjens, Inwood, Jansen, Kamphuisen, Kearney, Konkle, Kulkarni, Kulkarni, Laine, Lanas, Lanas, Lanza, Lin, Makris, Mannucci, Masso Gonzalez, McGettigan, Mittal, Odom, Ofman, Papatheodoridis, Park, Patrignani, Pergantou, Rattray, Riley, Rostom, Scarpignato, Scarpignato, Scarpignato, Schulman, Segasothy, Segasothy, Solomon, Soucie, Srivastava, Stephensen, Steven, Trelle, Tuskey, Van, White, Yeomans, Young   +75 more
core   +1 more source

Low-Grade Inflammation as a Predictor of Antidepressant and Anti-Inflammatory Therapy Response in MDD Patients: A Systematic Review of the Literature in Combination With an Analysis of Experimental Data Collected in the EU-MOODINFLAME Consortium

Frontiers in Psychiatry, 2019
Low-grade inflammation plays a role not only in the pathogenesis of major depressive disorder (MDD) but probably also in the poor responsiveness to regular antidepressants.
Gara Arteaga-Henríquez, Gara Arteaga-Henríquez, Gara Arteaga-Henríquez, Maria S. Simon, Bianka Burger, Elif Weidinger, Annemarie Wijkhuijs, Volker Arolt, Tom K. Birkenhager, Richard Musil, Norbert Müller, Norbert Müller, Hemmo A. Drexhage   +12 more
doaj   +1 more source

Anti-Inflammatory activity of a polyphenolic extract from Arabidopsis thaliana in in vitro and in vivo models of Alzheimer's Disease [PDF]

, 2019
Alzheimer's disease (AD) is the most common neurodegenerative disorder and the primary form of dementia in the elderly. One of the main features of AD is the increase in amyloid-beta (Aβ) peptide production and aggregation, leading to oxidative stress ...
Casale, Assunta Maria, Costantino, Paolo, D'Erme, Maria, Francioso, Antonio, Gazzino, Roberta, Mancini, Patrizia, Mattioli, Roberto, Mosca, Luciana, Piacentini, Lucia, Trovato, Maurizio, Wessjohann, Ludger   +10 more
core   +1 more source

Antimicrobial and anti-inflammatory activity of chitosan-alginate nanoparticles: a targeted therapy for cutaneous pathogens. [PDF]

, 2013
Advances in nanotechnology have demonstrated potential application of nanoparticles (NPs) for effective and targeted drug delivery. Here we investigated the antimicrobial and immunological properties and the feasibility of using NPs to deliver ...
Blecher-Paz, Karin, Champer, Jackson, Friedman, Adam J, Kim, Jenny, Liu, Phil T, Modlin, Robert L, Oren, Ami, Phan, Jenny, Pirouz, Aslan, Qin, Min, Schairer, David O   +10 more
core   +1 more source

Preliminary analysis of the anti-inflammatory activity of essential oils of Zingiber zerumbet [PDF]

, 2011
Nonsteroidal anti-inflammatory drugs (NSAIDs) have been widely used for the treatment of inflammation. However, despite their effectiveness, most NSAIDs cause various side effects that negatively affect the management of inflammation and, in part, pain ...
Ahmad, M. S., Israf Ali, Daud Ahmad, Lajis, Nordin, Mokhtar, A. F., Sulaiman, Mohd Roslan, Tengku Mohamad, Tengku Azam Shah, Zakaria, Zainul Amiruddin   +6 more
core   +1 more source

ANTI-INFLAMMATORY ACTIVITY OF BAWANG DAYAK (ELEUTHERINE BULBOSA (MILL. URB.))ETHANOL BULB EXTRACTS

Journal of Vocational Health Studies, 2019
Background: Inflammation is a normal process in response to injury, but causes problems for the patient, including the appearance of pain, swelling, or fever.
Swandari Paramita, Muhammad Khairul Nuryanto   +1 more
doaj   +1 more source

Tumor necrosis factor inhibitors in psoriatic arthritis. [PDF]

, 2017
INTRODUCTION: Psoriatic arthritis (PsA) is a chronic inflammatory disease that can result in significant disability. With the emergence of tumor necrosis factor inhibitors (TNFi), therapeutic outcomes in PsA have improved substantially.
Kraft, Walter K., Mantravadi, Santhi, Ogdie, Alexis   +2 more
core   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Expression of TIM3/VISTA checkpoints and the CD68 macrophage-associated marker correlates with anti-PD1/PDL1 resistance: implications of immunogram heterogeneity. [PDF]

, 2020
Although immunotherapies have achieved remarkable salutary effects among subgroups of advanced cancers, most patients do not respond. We comprehensively evaluated biomarkers associated with the "cancer-immunity cycle" in the pan-cancer setting in order ...
Dressman, Devin, Eskander, Ramez, Glenn, Sean T, Goodman, Aaron, Ikeda, Sadakatsu, Kato, Shumei, Kumaki, Yuichi, Kurzrock, Razelle, Lee, Suzanna, Lenzo, Felicia L, Morrison, Carl, Nikanjam, Mina, Okamura, Ryosuke, Papanicolau-Sengos, Antonios   +13 more
core   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source