Results 61 to 70 of about 905,676 (332)

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

Mushrooms as a Source of Anti-Inflammatory Agents

Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry, 2010
Inflammation is nowadays well known to be involved in the development of several chronic diseases such as arteriosclerosis, obesity, diabetes, neurodegenerative diseases, and cancer. Treatment for chronic inflammatory disorders has not been solved yet, and there is an urgent need to find new and safe anti-inflammatory preventive and therapeutic ...
García - Lafuente, A., Moro, C., Villares Garicochea, Ana, Guillamon, E., Rostagno, M. A., d'Arrigo, M., Martinez, J. A.   +6 more
openaire   +6 more sources

Repositioning drugs for inflammatory disease – fishing for new anti-inflammatory agents

Disease Models & Mechanisms, 2014
Inflammation is an important and appropriate host response to infection or injury. However, dysregulation of this response, with resulting persistent or inappropriate inflammation, underlies a broad range of pathological processes, from inflammatory ...
Christopher J. Hall, Sophie M. Wicker, An-Tzu Chien, Alisha Tromp, Lisa M. Lawrence, Xueying Sun, Geoffrey W. Krissansen, Kathryn E. Crosier, Philip S. Crosier   +8 more
doaj   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Anti-inflammatory agents of the carbamoylmethyl ester class: synthesis, characterization, and pharmacological evaluation

Journal of Inflammation Research, 2013
Bassem Sadek,1 Amar Mansuor Hamruoni,2 Abdu Adem1 1Department of Pharmacology and Therapeutics, College of Medicine and Health Sciences, United Arab Emirates University, 2Department of Pharmaceutical Sciences, College of Pharmacy, Al Ain University of ...
Sadek B, Hamruoni AM, Adem A
doaj  

The investigation of the effect of ozone therapy on gout in experimental rat models [PDF]

Kafkas Universitesi Veteriner Fakültesi Dergisi, 2019
The effect of ozone treatment in experimental rat gout arthritis was investigated. Twenty adult albino male rats were divided into 4 groups: Group 1 (Control) was followed without any medication, Group 2 (Gout control) was injected with a single dose of ...
Ali BİLGE, Murat TÜYSÜZ, Ömür ÖZTÜRK, Yasemen ADALI, Hüseyin Avni EROĞLU, Mustafa MAKAV, Gözde ATİLA USLU, Ramazan TISKAOĞLU   +7 more
doaj   +1 more source

Prophylactic Anticoagulant Treatment Might Have an Anti-inflammatory Effect and Reduce Mortality Rates in Hospitalized COVID-19 Patients?

Oman Medical Journal, 2022
Objectives: COVID-19 associated coagulopathy and prophylactic anticoagulant therapy (PAT) are ongoing topics globally. Using PAT for anti-inflammatory effect may prevent thromboembolic events (TEEs).
Sevil Alkan, Alper Şener, Ebru Doğan, Cihan Yüksel, Buse Yüksel   +4 more
doaj   +1 more source

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

FEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Anti-inflammatory Activity Of Bawang Dayak (Eleutherine Bulbosa (Mill. Urb.))ethanol Bulb Extracts [PDF]

, 2018
Background: Inflammation is a normal process in response to injury, but causes problems for the patient, including the appearance of pain, swelling, or fever.
Nuryanto, M. K. (Muhammad), Paramita, S. (Swandari)   +1 more
core  

Drug treatment of hypertension: focus on vascular health [PDF]

, 2016
Hypertension, the most common preventable risk factor for cardiovascular disease and death, is a growing health burden. Serious cardiovascular complications result from target organ damage including cerebrovascular disease, heart failure, ischaemic heart
Cameron, Alan C., Lang, Ninian N., Touyz, Rhian M.   +2 more
core   +1 more source