Results 21 to 30 of about 52,218 (248)

Jo-1 autoantigen-specific B cells are skewed towards distinct functional B cell subsets in anti-synthetase syndrome patients

Arthritis Research & Therapy, 2021
Background Anti-Jo-1 autoantibodies which recognize histidyl-tRNA synthetase identify patients with the rare rheumatologic disease, anti-histidyl-tRNA synthetase syndrome (Jo-1 ARS), a phenotypically distinct subset of idiopathic inflammatory myopathies (
Jennifer Young-Glazer, Alberto Cisneros, Erin M. Wilfong, Scott A. Smith, Leslie J. Crofford, Rachel H. Bonami   +5 more
doaj   +1 more source

Clinical Characteristics of Patients With Anti-Jo-1 Antibodies [PDF]

JCR: Journal of Clinical Rheumatology, 2009
The idiopathic inflammatory myopathies (IIM) are a group of autoimmune disorders, including polymyositis (PM), dermatomyositis (DM), inclusion body myositis, and myositis associated with malignancy and other connective tissue diseases. Both DM and PM can have associated interstitial lung disease (ILD).1,2 A number of autoantibodies, called myositis ...
Linda M, Mileti, Mary E, Strek, Timothy B, Niewold, James J, Curran, Nadera J, Sweiss   +4 more
openaire   +2 more sources

A subluxing arthropathy associated with the anti‐jo‐1 antibody in polymyositis/dermatomyositis [PDF]

Arthritis & Rheumatism, 1990
AbstractOf 180 patients with polymyositis/dermatomyositis (PM/DM) seen at the University of Pittsburgh and affiliated hospitals since 1975, 21 of 100 tested positive for the anti‐Jo‐1 antibody. Sixteen of the 21 patients were women and 18 were white. Fifteen had adult PM, 4 had myositis in overlap with scleroderma, and 2 had adult DM.
C V, Oddis, T A, Medsger, L A, Cooperstein   +2 more
openaire   +2 more sources

Myositis-specific and myositis-associated autoantibody profiles and their clinical associations in a large series of patients with polymyositis and dermatomyositis

Clinics, 2013
OBJECTIVE: To analyze the prevalence of myositis-specific and myositis-associated autoantibodies and their clinical correlations in a large series of patients with dermatomyositis/polymyositis.
Marcela Gran Pina Cruellas, Vilma dos Santos Trindade Viana, Maurício Levy-Neto, Fernando Henrique Carlos de Souza, Samuel Katsuyuki Shinjo   +4 more
doaj   +1 more source

Anti–Jo-1–Positive Antisynthetase Syndrome and Myocarditis: An Underrecognized Clinical Presentation

Annals of Internal Medicine: Clinical Cases, 2023
Antisynthetase syndrome is a distinct entity of overlap myositis in adults and is characterized by muscle weakness, arthritis, mechanic's hands, interstitial lung disease, and Raynaud phenomenon.
Rania Al Asmar, Rabia Cheema, Samera Vaseer, Ira Targoff, Mary Beth Humphrey   +4 more
doaj   +1 more source

Perifascicular necrosis in anti-synthetase syndrome beyond anti-Jo-1 [PDF]

Brain, 2016
Sir, The papers by Mescam-Mancini et al. (2015) and Stenzel et al. (2015) are of particular interest, at least partially addressing the important question whether anti-synthetase syndrome is pathologically distinct from other idiopathic inflammatory myopathies. Mescam-Mancini et al.
Akinori, Uruha, Shigeaki, Suzuki, Norihiro, Suzuki, Ichizo, Nishino   +3 more
openaire   +2 more sources

Interstitial Lung Disease in Anti–Jo‐1 Patients With Antisynthetase Syndrome [PDF]

Arthritis Care & Research, 2013
Abstract Objective To assess the outcome of interstitial lung disease (ILD) in anti–Jo‐1 patients with antisynthetase syndrome, determine predictive variables of ILD deterioration in these patients, and compare features of anti–Jo‐1 patients with and without ILD.
I, Marie, S, Josse, P Y, Hatron, S, Dominique, E, Hachulla, A, Janvresse, P, Cherin, L, Mouthon, O, Vittecoq, J-F, Menard, F, Jouen   +10 more
openaire   +2 more sources

Pericardial effusion in idiopathic inflammatory myopathies: A cross-sectional study from Asia and review of the literature

International Journal of Immunopathology and Pharmacology, 2022
Objectives Pericardial effusion is a rare clinical manifestation in idiopathic inflammatory myopathies (IIMs). It has been described in a small number of literature studies worldwide.
Yue Wang, Qiang Zeng, Xuanlin Cai, Yan Meng, Chenxi Zhang, Jiahui Fan, Madinaimu Aibibula, Ning Feng, Li Luo, Xiumin Ma   +9 more
doaj   +1 more source

Anti-Jo-1 Syndrome presenting as cryptogenic organizing pneumonia

Respiratory Medicine, 1995
AbstractA 50-year-old Chinese lady presented with subacute onset of dyspnoea, bilateral infiltrates on chest X-ray and type I respiratory failure. There were minor symptoms of arthralgia and myalgia. Subsequent investigations confirmed that she had organizing pneumonia, polymyositis and serum anti-Jo-1 antibody.
Wang, E, Peh, WCG, Chan, WM, Lau, CS, Ip, M   +4 more
openaire   +4 more sources

The pulmonary histopathologic manifestations of the anti-Jo-1 tRNA synthetase syndrome [PDF]

Modern Pathology, 2010
Of the idiopathic inflammatory myopathies, the anti-aminoacyl tRNA synthetase syndrome has the greatest association with interstitial lung disease (ILD). We reviewed 13 open surgical lung biopsies, four autopsies, and three native lungs resected at transplantation, for pulmonary ILD associated with the presence of anti-histidyl tRNA synthetase (anti-Jo-
Samuel A, Yousem, Kevin, Gibson, Naftali, Kaminski, Chester V, Oddis, Dana P, Ascherman   +4 more
openaire   +2 more sources