Results 31 to 40 of about 52,218 (248)

Myositis specific and myositis associated autoantibodies in idiopathic inflammatory myopathies: a serologic study of 46 patients

Reumatismo, 2011
Objective. To characterize serum autoantibody profiles of patients with idiopathic inflammatory myopathies (IIM) by searching for myositis-specific (MSA) and myositis-associated (MAA) antibodies with sensitive and specific laboratory tests. Methods.
R. Rondinone, R. Bendo, M. Tonello, E. Tarricone, L. Iaccarino, S. Zampieri, A. Ghirardello, F. Cozzi, A. Doria   +8 more
doaj   +1 more source

A case of polymyositis with anti-Jo-1 antibody preceded by BOOP.

Japanese Journal of Clinical Immunology, 1998
A 56-year-old man experienced dyspnea since August 1995 and the chest X-ray film showed abnormal shadow. The diagnosis of bronchiolitis obliterans organizing pneumonia (BOOP) was established based on the histological findings of transbronchial lung biopsy. The patient was treated with prednisolone and symptoms improved.
Takahashi, Hiroki, Matsumoto, Takeshi, Abe, Tamaki, Sato, Shuji, Hamamoto, Yasuo, Mita, Hiroaki, Matsunaga, Takahiro, Miyachi, Toshiki, Makiguchi, Yusuke, Imai, Kohzoh, Saito, Tsukasa, Watanabe, Koshiro, Nakamura, Nobuo   +12 more
openaire   +3 more sources

Doença pulmonar intersticial relacionada a miosite e a síndrome antissintetase Myositis-related interstitial lung disease and antisynthetase syndrome

Jornal Brasileiro de Pneumologia, 2011
Em pacientes com miosite, é comum o comprometimento pulmonar, e a presença de anticorpos anti-aminoacil-RNAt sintetase (anti-ARS) é preditora da presença ou do desenvolvimento de doença pulmonar intersticial (DPI).
Joshua Solomon, Jeffrey J Swigris, Kevin K Brown   +2 more
doaj   +1 more source

Clinical features of anti-synthetase syndrome associated interstitial lung disease: a retrospective cohort in China

BMC Pulmonary Medicine, 2021
Background Anti-synthetase syndrome (ASSD) is a chronic autoimmune condition characterized by antibodies directed against an aminoacycl transfer RNA synthetase (ARS) along with a group of clinical features including the classical clinical triad ...
Xi Zhan, Wei Yan, Ying Wang, Qing Li, Xuhua Shi, Yanli Gao, Qiao Ye   +6 more
doaj   +1 more source

Síndrome Antissintetase: relato de dois casos e revisão da literatura

Revista Brasileira de Reumatologia, 2015
A Síndrome Antissintetase (SAS) é caracterizada por miosite, fenômeno de Raynaud, febre, doença pulmonar intersticial, artropatia e mãos de mecânico associados à presença de anticorpos contra a sintetase do RNAt especialmente anti-Jo-1.
Lívia Regina Theilacker, Fabíola Sampaio Brandão, Fernanda Velloso Goulart, João Luiz Pereira Vaz, Luiz Octávio Dias D'Almeida, Maria Cecília da Fonseca Salgado   +5 more
doaj   +1 more source

High-Throughput Detection of Autoantigen-Specific B Cells Among Distinct Functional Subsets in Autoimmune Donors

Frontiers in Immunology, 2021
Antigen-specific B cells (ASBCs) can drive autoimmune disease by presenting autoantigen to cognate T cells to drive their activation, proliferation, and effector cell differentiation and/or by differentiating into autoantibody-secreting cells ...
Bryan A. Joosse, James H. Jackson, James H. Jackson, Alberto Cisneros, Austin B. Santhin, Scott A. Smith, Scott A. Smith, Scott A. Smith, Daniel J. Moore, Daniel J. Moore, Daniel J. Moore, Leslie J. Crofford, Leslie J. Crofford, Leslie J. Crofford, Erin M. Wilfong, Erin M. Wilfong, Rachel H. Bonami, Rachel H. Bonami, Rachel H. Bonami   +18 more
doaj   +1 more source

Biphasic Clinical Course of Pediatric Cytomegalovirus‐Associated Immune Thrombocytopenia: Early Poor Treatment Response but Favorable Long‐Term Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cytomegalovirus (CMV) is a recognized trigger of immune thrombocytopenia (ITP); however, its incidence and impact on disease course in children remain controversial. Therefore, we aimed to characterize the clinical course of pediatric patients with CMV‐associated ITP.
Oded Gilad, Ohad Atia, Osama Tanous, Dafna Brik Simon, Michal Dvori, Miriam Cohen, Tracie A. Goldberg, Efraim Bilavsky, Joanne Yacobovich, Orna Steinberg‐Shemer   +9 more
wiley   +1 more source

Anti-synthetase syndrome

Journal of Clinical and Scientific Research, 2019
We report the case of a 39-year-old female who presented with breathlessness on exertion, cough, myalgias for the past 6 months and fever for 1 month. Chest X-ray revealed bilateral multilobar consolidation.
V Arun Raja, J Harikrishna, M Ganesh, C Rahul, A Praveen, S Aparna Reddy, Alladi Mohan   +6 more
doaj   +1 more source

Pneumopathie infiltrante diffuse secondaire à un syndrome des antisynthétases: à propos d´un cas

The Pan African Medical Journal, 2021
Les pneumopathies infiltrantes diffuses (PID) constituent une manifestation fréquente des connectivites. Elles peuvent être révélatrices de la maladie ou survenir au cours du suivi.
Nadia Moussa, Rim Khemakhem, Mouna Snoussi, Wafa Fekih, Zouhir Bahloul, Sami Kammoun   +5 more
doaj   +1 more source

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

FEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park, Inho Kwon, Yong Hwan Kim, Ji‐Eun Bae, Joon Bum Kim, Seong Hyun Kim, Sungho Maeng, Doo Sin Jo, Dong‐Hyung Cho   +8 more
wiley   +1 more source