Results 41 to 50 of about 7,359,914 (273)

Protection against dengue virus infection in mice by administration of antibodies against modified nonstructural protein 1. [PDF]

open access: yesPLoS ONE, 2014
BACKGROUND: Infection with dengue virus (DENV) may cause life-threatening disease with thrombocytopenia and vascular leakage which are related to dysfunction of platelets and endothelial cells.
Shu-Wen Wan   +9 more
doaj   +1 more source

Cytophilic Antibodies to Plasmodium Falciparum Glutamate Rich Protein are Associated with Malaria Protection in an Area of Holoendemic Transmission. [PDF]

open access: yes, 2005
Several studies conducted in areas of medium or low malaria transmission intensity have found associations between malaria immunity and plasma antibody levels to glutamate rich protein (GLURP).
Thor G Theander   +23 more
core   +1 more source

Additional file 1 of Evolution of anti-modified protein antibody responses can be driven by consecutive exposure to different post-translational modifications

open access: yes, 2021
Additional file 1: Supplementary Methods. Calculation of summary titer evolution (as implemented for Fig. 2D). Supplementary Table 1. CCP2 ELISA measurements prior to the study. Supplementary Table 2. Supplementary Table 3. Changes in AMPA status in the IMPROVED cohort. Supplementary Table 4. Overview of the mice immunization groups.
Volkov, M.   +9 more
openaire   +1 more source

Clinical Features and Prognosis in Chinese Patients With Dipeptidyl–Peptidase–Like Protein 6 Antibody–Associated Encephalitis

open access: yesFrontiers in Neurology, 2022
Objectives:Anti-dipeptidyl–peptidase–like protein 6 (anti-DPPX) encephalitis an extremely rare type of immune-mediated encephalitis. This study aimed to analyze the electroclinical characteristics and prognosis of anti-DPPX encephalitis.Methods:Five ...
Ailiang Miao   +5 more
doaj   +1 more source

Differential ACPA Binding to Nuclear Antigens Reveals a PAD-Independent Pathway and a Distinct Subset of Acetylation Cross-Reactive Autoantibodies in Rheumatoid Arthritis

open access: yesFrontiers in Immunology, 2019
Rheumatoid arthritis (RA) associated anti-citrullinated protein autoantibodies (ACPA) target a wide range of modified proteins. Citrullination occurs during physiological processes such as apoptosis, yet little is known about the interaction of ACPA with
Katy A. Lloyd   +25 more
doaj   +1 more source

Characterization of immunoglobulin G antibodies to Plasmodium falciparum sporozoite surface antigen MB2 in malaria exposed individuals [PDF]

open access: yes, 2009
Background MB2 protein is a sporozoite surface antigen on the human malaria parasite Plasmodium falciparum. MB2 was identified by screening a P. falciparum sporozoite cDNA expression library using immune sera from a protected donor immunized via the ...
James Anthony A   +30 more
core   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Covalent functionalization of silicon nitride surfaces for anti-biofouling and bioselective capture [PDF]

open access: yes, 2011
Microsieves – microengineered membranes – have been introduced in microfiltration technology as a new generation of inorganic membranes. The thin membranes are made of silicon nitride (SixN4), which gives the membranes outstanding features, such as ...
Nguyen, A.T.
core  

Anti-modified citrullinated vimentin antibody: a novel biomarker associated with cardiac systolic dysfunction in patients with rheumatoid arthritis

open access: yesBMC Cardiovascular Disorders, 2020
Background Studies have demonstrated that seropositive patients with rheumatoid arthritis (RA) are susceptible to cardiovascular diseases (CVDs). In this study, we aimed to determine the association of autoantibodies with the echocardiographic parameters
Somayye Norouzi   +3 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

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