Results 1 to 10 of about 44,692 (253)

Discovery of new quaternized norharmane dimers as potential anti-MRSA agents [PDF]

Journal of Advanced Research
Introduction: Methicillin-resistant Staphylococcus aureus (MRSA)-caused infections greatly threaten public health. The discovery of natural-product-based anti-MRSA agents for treating infectious diseases has become one of the current research focuses ...
Jiang-Kun Dai, Wen-Jia Dan, Yi-Dan Cao, Ji-Xiang Gao, Jun-Ru Wang, Jian-Bo Wan   +5 more
doaj   +4 more sources

Discovery of Brominated Alboflavusins With Anti-MRSA Activities [PDF]

Frontiers in Microbiology, 2021
As methicillin-resistant Staphylococcus aureus (MRSA) is becoming a serious pathogenic threaten to human health worldwide, there is an urgent need to discover new antibiotics for the treatment of MRSA infections.
Chao Li, Chao Li, Wuyundalai Bao, Haoyue Zhang, Zhitang Lyu, Yihua Chen, Yihua Chen, Zhengyan Guo, Zhengyan Guo   +8 more
doaj   +3 more sources

In vitro anti-biofilm effect of anti-methicillin-resistant Staphylococcus aureus (anti-MRSA) agents against the USA300 clone

Journal of Global Antimicrobial Resistance, 2021
Objectives: Infection with a typical community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA), the USA300 clone, has become a worldwide epidemic.
Hiroshi Kaneko, Hidemasa Nakaminami, Kosuke Ozawa, Takeaki Wajima, Norihisa Noguchi   +4 more
doaj   +3 more sources

Effect of Early Administration of Anti‐MRSA Drugs for Febrile Neutropenia in Allogeneic Hematopoietic Cell Transplantation [PDF]

eJHaem
Background In febrile neutropenia (FN), the empirical use of anti‐methicillin‐resistant Staphylococcus aureus (MRSA) drugs is recommended, particularly when mucosal damage occurs during fluoroquinolone antibiotic administration.
Anna Akaogi, Junya Kanda, Fumiya Wada, Yasuyuki Arai, Chisaki Mizumoto, Toshio Kitawaki, Kouhei Yamashita, Akifumi Takaori‐Kondo   +7 more
doaj   +2 more sources

Novel Thiazolylketenyl Quinazolinones as Potential Anti-MRSA Agents and Allosteric Modulator for PBP2a [PDF]

Molecules, 2023
Bacterial infections caused by methicillin-resistant Staphylococcus aureus have seriously threatened public health. There is an urgent need to propose an existing regimen to overcome multidrug resistance of MRSA.
Jie Dai, Narsaiah Battini, Zhonglin Zang, Yan Luo, Chenghe Zhou   +4 more
doaj   +2 more sources

Apium graveolens-associated Aspergillus sp.: metabolomic profiling and anti-MRSA potential supported by in silico studies [PDF]

Microbial Cell Factories
Methicillin-resistant Staphylococcus aureus (MRSA) is a significant pathogen associated with healthcare-related infections that are often challenging to treat.
Alshymaa Abdel-Rahman Gomaa, Hesham A. Abou-Zied, Sara Mahmoud Farhan, Ruqaiah I. Bedaiwi, Mohammad A. Alanazi, Stefanie P. Glaeser, Peter Kämpfer, Usama Ramadan Abdelmohsen, Fatma Alzahraa Mokhtar, Enas Reda Abdelaleem   +9 more
doaj   +2 more sources

Implementation of MRSA Nasal Swabs as an Antimicrobial Stewardship Intervention to Decrease Anti-MRSA Therapy in COVID-19 Infection

Antibiotics, 2023
In the early stages of treating patients with SARS-CoV-2, limited information was available to guide antimicrobial stewardship interventions. The COVID-19 Task Force and Antimicrobial Stewardship Committee, at a 988-bed academic medical center ...
Alaina DeKerlegand, Emily Johnston, Britney Mellor, Melanie Rae Schrack, Catherine O’Neal   +4 more
doaj   +1 more source

Evaluation of Anti-Methicillin-Resistant Staphylococcus aureus (MRSA) Prescribing Habits in Patients with a Positive MRSA Nasal Swab in the Absence of Positive Cultures

Pharmacy, 2023
Methicillin-resistant Staphylococcus aureus (MRSA) polymerase chain reaction (PCR) nasal swabs are guideline-recommended de-escalation tools in certain patients with pneumonia.
Madeline Pelham, Madeline Ganter, Joshua Eudy, Daniel T. Anderson   +3 more
doaj   +1 more source

Intradermal immunization with wall teichoic acid (WTA) elicits and augments an anti-WTA IgG response that protects mice from methicillin-resistant Staphylococcus aureus infection independent of mannose-binding lectin status. [PDF]

PLoS ONE, 2013
The objectives of this study were to investigate the immune response to intradermal immunization with wall teichoic acid (WTA) and the effect of MBL deficiency in a murine model of infection with methicillin-resistant Staphylococcus aureus (MRSA). WTA is
Kazue Takahashi, Kenji Kurokawa, Patience Moyo, Dong-Jun Jung, Jang-Hyun An, Lorencia Chigweshe, Elahna Paul, Bok Luel Lee   +7 more
doaj   +1 more source

Evaluation of the Effectiveness and Use of Anti-Methicillin-Resistant Staphylococcus aureus Agents for Aspiration Pneumonia in Older Patients Using a Nationwide Japanese Administrative Database

Microorganisms, 2023
Studies indicated potential harm from empirical broad-spectrum therapy. A recent study of hospitalizations for community-acquired pneumonia suggested that empirical anti-methicillin-resistant Staphylococcus aureus (MRSA) therapy was associated with an ...
Satoru Koga, Takahiro Takazono, Takashi Kido, Keiji Muramatsu, Kei Tokutsu, Takatomo Tokito, Daisuke Okuno, Yuya Ito, Hirokazu Yura, Kazuaki Takeda, Naoki Iwanaga, Hiroshi Ishimoto, Noriho Sakamoto, Kazuhiro Yatera, Koichi Izumikawa, Katsunori Yanagihara, Yoshihisa Fujino, Kiyohide Fushimi, Shinya Matsuda, Hiroshi Mukae   +19 more
doaj   +1 more source