Results 71 to 80 of about 1,883,497 (302)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Christian Anti-Communism Crusade - Application for membership [PDF]

, 1962
Christian Anti-Communism Crusade - Application for ...
Christian Anti-Communism Crusade
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Anti-dumping Policy and Anti-dumping Retaliation [PDF]

, 2016
This paper analyzes the incentives to petition for anti-dumping protection in the context of anti-dumping retaliation. We examine how anti-dumping retaliation may arise and whether such retaliation can be a threat that dissuades a domestic firm facing ...
Chen, Chin-Sheng;Kao, Kuo-Feng, Chin-Sheng Chen; Kuo-Feng Kao   +1 more
core  

Export of nutrients from the Arctic Ocean [PDF]

, 2013
This study provides the first physically based mass-balanced transport estimates of dissolved inorganic nutrients (nitrate, phosphate, and silicate) for the Arctic Ocean.
Tsubouchi, T., Whitledge, T.E., Azetsu-Scott, K., Naveira-Garabato, A.C., Petrie, Brian, Torres-valdes, Sinhué, Sanders, Richard, McLaughlin, Fiona A., Azetsu-Scott, Kumiko, Whitledge, Terry E., Sanders, Richards, Sanders, R., Tsubouchi, Takamasa, Kattner, Gerhard, Torres-Valdes, S., McLaughlin, F. A., Bacon, Sheldon, Naveira-Garabato, Alberto C., Petrie, B., Bacon, S.   +19 more
core   +1 more source

Lactic Acid Fermentation Ameliorates Intrinsic Toxicants in Brassica campestris L. Leaves Harvested at Different Growth Stages

Foods
Brassica campestris (syn. Brassica rapa) is often known as mustard and is grown worldwide owing to its health-promoting characteristics associated with the presence of nutrients and phytochemicals. Along with the nutritional components, B.
Muhammad Younis, Saeed Akhtar, Tariq Ismail, Muhammad Qamar, Dur-e-shahwar Sattar, Wisha Saeed, Mohammad S. Mubarak, Elena Bartkiene, João Miguel Rocha   +8 more
doaj   +1 more source

REVIEW OF MODERN TECHNOLOGIES FOR INACTIVATION OF ANTI-NUTRIENTS IN SOYBEANS

ENGINEERING, ENERGY, TRANSPORT AIC
The study examines technologies for inactivating anti-nutrients in soybeans, such as proteolytic enzyme inhibitors. In addition, soybeans have two trypsin inhibitors that bind cystine and methionine. Protease inhibitors include trypsin and chymotrypsin inhibitors, which are substances that are naturally present in soybeans to protect them from being ...
Ihor KUPCHUK, Yevhenii VOLYNETS, Oleh SIMAKOV   +2 more
openaire   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Christian Anti-Communism Crusade - Invitation to a lecture by Dr. F. Schwarz, President of the Christian Anti-Communism Crusade [PDF]

, 1963
Christian Anti-Communism Crusade - Invitation to a lecture by Dr. F.
Christian Anti-Communism Crusade
core  

Effects of thermo-mechanical and chemical processes on the nutritional and functional quality of Sacha inchi (Plukenetia volubilis) flour

Frontiers in Sustainable Food Systems
The objective of this study was to subject Sacha inchi (TA) kernels to mechanical (TST), thermo- mechanical (TCT), and chemical (TMH) processes with the aim of obtaining cakes with a high protein content.
Ruby Aracely Narváez Cadena, Diego Fernando Roa Acosta, Jesús Eduardo Bravo Gómez   +2 more
doaj   +1 more source