Results 111 to 120 of about 2,119,412 (309)

Inhibitors of absorption as anti-obesity drugs.

Folia Pharmacologica Japonica, 2001
There are two types of anti-obesity agents which are classified as inhibitors of absorption: inhibitors of lipid and carbohydrate absorption. Inhibitors of lipid absorption consist of lipase inhibitor (orlistat, Nomma Herb's extract (CT-II) and fat substitute (olestra, sucrose polyester). Orlistat is now available as an anti-obesity drug in the USA and
TSUJI, Masatomi, SAITO, Nobuhiko, INOUE, Shuji   +2 more
openaire   +3 more sources

Tropomyosin 1 Promotes Platelet Adhesion and Clot Contraction Separate from Its Roles in Developmental Hematopoiesis

Advanced Science, EarlyView.
ABSTRACT Genome‐wide association studies (GWAS) link the Tropomyosin 1 (Tpm1) locus to quantitative blood trait variation, but related mechanisms are unclear. Tpm1 encodes an actin‐binding protein that regulates actin filament diversity, cell adhesion, signaling, and actomyosin contractility.
Po‐Lun Kung, Victor Tsao, Alina D Peshkova, Oscar A. Marcos‐Contreras, Kim Ha, Brian M Dulmovits, Nkemdilim Okoli, Anvi Sinha, Gennadiy Fonar, Rong Qiu, Rolf D Bates, Janelle Yeboah, Carson Shalaby, Tyler Truex, Soomin Jeong, Edna C Hardeman, Peter W Gunning, Vladimir R Muzykantov, Jacob W Myerson, Christopher S Thom   +19 more
wiley   +1 more source

Profile of High Obesity Areas in: North Carolina [PDF]

Obesity is a major health problem on a national level, butit is particularly persistent in certain areas. The Centersfor Disease Control and Prevention\u2019s (CDC) Programs toReduce Obesity in High Obesity Areas to Boost Preventioncooperative agreement ...

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Rise and fall of anti-obesity drugs

World Journal of Diabetes, 2011
Although it is not generally a life-threatening disease, obesity is becoming a major health problem worldwide. It can be controlled by means of drugs, and, consequently, these are required to be safe as well as effective. In this paper, we summarize the fate of various drugs that have been introduced for clinical use in the treatment of obesity ...
Cheung, BMY, Li, MF
openaire   +4 more sources

CD4+ Tregs Drive Post‐Ischemic Sprouting Angiogenesis via Endothelial YY1/MAML1 Reactivation

Advanced Science, EarlyView.
ABSTRACT Microvascular complications of diabetes are chronic diseases of small vessels. We previously found that CD4+ regulatory T‐cells (Tregs) are markedly reduced in type 2 diabetes (T2D) after ischemic injury in both mice and humans, and that Treg deficiency in immunodeficient mice impairs vascular regeneration.
Hang Qu, Cheng Kiu Ho, Jitao Liu, Lei Cui, Yangfeng Hou, Cai Liang, Wenchu Ye, Randolph H. L. Wong, Shohei Hori, Bin Zhou, Kathy O. Lui   +10 more
wiley   +1 more source

Combating Childhood Obesity in West Virginia: West Virginia University's High Obesity Program [PDF]

CDC\u2019s High Obesity Program (HOP) promotes healthy eating and active living in counties that have more than 40% prevalence of adult obesity. CDC provides funds to universities that work with communities \u2014mostly in rural areas\u2014whose ...

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Childhood obesity and educational attainment : A systematic review [PDF]

, 2011
Background This report describes the findings and methods of a systematic review of research which explores the relationship between obesity and educational attainment.
Kavanagh, J, Oliver, S, Stansfield, Claire, Caird, Jenny, O'Mara, Alison, Oliver, K, Oliver, Sandy, O’Mara, A, Caird, J, Kavanagh, Josephine, Thomas, James, O'Mara, A, Stansfield, C, Oliver, Kathryn, Thomas, J   +14 more
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m6A‐Mediated Glycolysis by IL‐37 Drives T Cell Metabolic Reprogramming to Regulate Colitis

Advanced Science, EarlyView.
This study identifies an IL‐37/SIGIRR‐METTL14 regulatory axis that suppresses global m6A modification in CD4+ T cells. IL‐37 signaling, mediated through SIGIRR, inhibits IRAK4 and JNK phosphorylation, leading to downregulation of the methyltransferase METTL14.
Xiaoyan Wang, Jiadong Yu, Guolin Li, Ya Li, Fanlian Zeng, Jing Hu, Yifan Zhou, Chengcheng Yue, Qixiang Zhao, Chen Zhang, Hong Zhou, Fulei Zhao, Yawen Hu, Pei Zhou, Linna Gu, Yuting Feng, Mingxiang He, Shishi Huang, Xiaochi Sun, Xinmeng Wang, Jie Tang, Xinyu Zeng, Wenling Wu, Nongyu Huang, Xinai Cui, Kaijun Cui, Jiong Li   +26 more
wiley   +1 more source

Anti-obesity efficacy of nanoemulsion oleoresin capsicum in obese rats fed a high-fat diet [PDF]

, 2014
Joo-Yeon Kim,1,* Mak-Soon Lee,1,* Sunyoon Jung,1 Hyunjin Joo,1 Chong-Tai Kim,2 In-Hwan Kim,3 Sangjin Seo,1 Soojung Oh,1 Yangha Kim11Department of Nutritional Science and Food Management, Ewha Womans University, Seoul, Republic of Korea; 2Functional ...
Seo S, Lee MS, Joo H, Kim JY, Kim IH, Kim CT, Oh S, Kim Y, Jung S   +8 more
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Increasing Obesity in Treated Female HIV Patients from Sub-Saharan Africa: Potential Causes and Possible Targets for Intervention. [PDF]

, 2014
Objectives: To investigate changing nutritional demographics of treated HIV-1-infected patients and explore causes of obesity, particularly in women of African origin. Methods: We prospectively reviewed nutritional demographics of clinic attenders at
Macallan, DC, Kim eIliffe, Kim Iliffe, Arianne M. Francis, Mark ePakianathan, Helen eWebb, Helen Webb, Douch, CJ, Claire eMcCormick, Mark Pakianathan, Claire L. McCormick, Derek C. Macallan, McCormick, CL, Webb, H, Pakianathan, M, Iliffe, K, Catherine J Douch, Arianne M Francis, Derek eMacallan, Catherine J. Douch, Francis, AM   +20 more
core   +1 more source