Results 121 to 130 of about 2,119,412 (309)

Seleção de extratos brutos de plantas com atividade antiobesidade Selection of crude plant extracts with anti-obesity activity

Revista Brasileira de Plantas Medicinais, 2012
A prevalência da obesidade está aumentando a um ritmo alarmante e poucos medicamentos para o tratamento estão atualmente disponíveis no mercado. A inibição da lipase pancreática é um dos mecanismos mais amplamente estudados para determinar a eficácia de ...
S.P. Souza, L.L.S. Pereira, A.A. Souza, C.D. Santos   +3 more
doaj  

Evaluation of Anti-Obesity and Antidiabetic Activities of Orostachys japonicus in Cell and Animal Models

Pharmaceuticals
Orostachys japonicus is a popular traditional medicinal herb used in Asian countries. This study is focused on evaluating its role in lipid and glucose metabolism in cell and animal models to establish the plant as an anti-obesity and antidiabetic herb ...
Ramakanta Lamichhane, Prakash Raj Pandeya, Kyung-Hee Lee, Gopal Lamichhane, Jae-Young Cheon, Hyo Shin Park, Nguyen Quoc Tuan, Hyun-Ju Jung   +7 more
doaj   +1 more source

Amuc_1473 Links Gut Microbes to Skeletal Homeostasis and Counteracts Multifactorial Osteoporosis

Advanced Science, EarlyView.
Amuc_1473, a previously uncharacterized protein enriched in Akkermansia muciniphila‐derived extracellular vesicles, is identified as a gut–bone messenger that promotes osteogenesis and inhibits osteoclastogenesis by engaging transcriptional and translational regulators in bone cells.
Shan‐Shan Rao, Hai‐Jin Zeng, Zun Wang, Chun‐Gu Hong, Yi‐Juan Tan, Yan‐Xin Duan, Jing‐Yao Luo, Ming‐Jie Luo, Yi‐Wei Liu, Xin Wang, Yi Luo, Teng‐Fei Wan, Yong Zhou, Zheng‐Guang Wang, Guo‐Wen Hu, Hao Yin, Xin‐Yue Hu, Zhen‐Xing Wang, Ze‐Hui He, Si‐Yi Cheng, Wei Du, Zhe Guan, Hai‐Li Lang, Hong‐Ji Liu, Jia Cao, Peng Chen, Jiang‐Hua Liu, Hui Xie, Chun‐Yuan Chen   +28 more
wiley   +1 more source

Obesity Prevention Effects of Avocado (Persea americana) Seed Powder in High-Fat Diet-Induced Obesity in Rats

Nutraceuticals
Avocado seed contains 64% of the phenolic compounds of the whole fruit. This makes avocado seed a potential candidate for the development of treatments for different illnesses, including obesity (the major risk factor for metabolic disorders). The aim of
Shoeshoe Mokhele, Oluwaseyi Aboyade, David R. Katerere   +2 more
doaj   +1 more source

Gut Microbiota, Immunity, and Metabolism in the Progression From Chronic Liver Disease to Hepatocellular Carcinoma

Advanced Science, EarlyView.
This review explains how chronic liver injury progresses toward hepatocellular carcinoma through interconnected changes in gut microbes, metabolism, immunity, fibrosis, and diet. It highlights microbial metabolites, bile‐acid signaling, immune dysfunction, and nutritional or microbiome‐based interventions as opportunities to identify risk earlier ...
Yi Hu, Caiyan Lin, Lijie Zhang, Xue Jiang, Huawen Li, Yangzhe Wu   +5 more
wiley   +1 more source

Knowledge and attitudes of obesity in university students [PDF]

, 2012
This paper reviews the literature which has measured individual’s knowledge on the health risks associated with obesity, and individual’s attitudes towards obese persons.
Giglia, Melissa
core  

Fat Mass and Obesity-Associated Gene (FTO) in Eating Disorders: Evidence for Association of the rs9939609 Obesity Risk Allele with Bulimia nervosa and Anorexia nervosa [PDF]

, 2012
Objective: The common single nucleotide polymorphism (SNP) rs9939609 in the fat mass and obesity-associated gene (FTO) is associated with obesity. As genetic variants associated with weight regulation might also be implicated in the etiology of eating ...
Wichmann, Heinz-Erich, Herzog, Wolfgang, Estivill, X., Fichter, Manfred, Sorbi, S., Ribasés Haro, Marta, Herpertz-Dahlmann, B., Hebebrand, J., Ehrlich, Stefan, Greene, B. H., Müller, Timo D., Estivill, Xavier, Fernandez-Aranda, Fernando, Scherag, Susan, Cavallini, M. C., Hebebrand, Johannes, Schäfer, Helmut, Ribases, Marta, Sorbi, Sandro, Herpertz Dahlmann, Beate, Lehmkuhl, Ulrike, Grallert, Harald, Fleischhaker, C., Wichmann, H.-E., Illig, T., Bellodi, L., Herzog, W., Fichter, M., Cellini, E., Bellodi, Laura, Ricca, Valdo, Fleischhaker, Christian, Scherag, Susann, Di Bella, D., Bella, Daniela Di, Cavallini, M.C., Scherag, S., Nacmias, Benedetta, Greene, B.H., Illig, Thomas, Schäfer, H., Fernández Aranda, Fernando, Fernández-Aranda, F., Di Bella, Daniela, Gratacòs, Monica, Erzegovesi, S., Cellini, Elena, Scherag, Andre, Fichter, Manfred M., Greene, Brandon H., Müller, T. D., Grallert, H., Nacmias, B., Hinney, A., Hinney, Anke, Erzegovesi, Stefano, Ribasés, M., Scherag, A., Wichmann, H. E., Müller, T.D., Cavallini, Maria C., Herpertz-Dahlmann, Beate, Estivill, Xavier, 1955-, Gratacòs, M., Ricca, V., Ehrlich, S., Lehmkuhl, U., Wichmann, H.-Erich   +67 more
core   +1 more source

An Implantable Optogenetics‐Engineered Hydrogel for Amelioration of Rheumatoid Arthritis through Light‐Controlled Metabolic Reprogramming of Synovial Macrophages

Advanced Science, EarlyView.
An implantable hydrogel is designed to enable in situ and on‐demand secretion of GLP‐1 in synovium through blue light irradiation to activate GLP‐1R/HK2/VDAC1 pathway for upregulating tricarboxylic acid cycle and oxidative phosphorylation in macrophage, facilitating tissue repair and bone erosion recovery.
Dahai Hu, Yaru Sun, Qi Lu, Yi Zhang, Jieruo Li, Huige Hou, Huajun Wang, Hui Tang, Yunsong Zhang, Xiaofei Zheng, Qingsong Mei   +10 more
wiley   +1 more source

Is BMI alone a sufficient outcome to evaluate interventions for child obesity? [PDF]

, 2013
BACKGROUND: BMI is often used to evaluate the effectiveness of childhood obesity interventions, but such interventions may have additional benefits independent of effects on adiposity.
Kapetanakis, V, Kolotourou, M, Singhal, Atul, Kapetanakis, Venediktos, Cole, Tim J., Singhal, A, Smith, Lindsey, Orfanos, Stravos, Chadwick, Paul, Chadwick, P, Sacher, Paul M., Orfanos, S, Kolotourou, Maria, Radley, Duncan, Radley, D, Smith, L, Cole, TJ, Sacher, PM, Orfanos, Stavros   +18 more
core   +1 more source

Brown Adipocyte Sheets Alleviate Myocardial Ischemia–Reperfusion Injury Through NRG4–ErbB4–Dependent Ferroptosis Inhibition

Advanced Science, EarlyView.
Brown adipocyte sheets are engineered to protect the heart against myocardial ischemia–reperfusion injury by restraining ferroptosis. Upon transplantation onto the cardiac surface, they improve cardiac function, limit infarction and fibrosis, and enhance angiogenesis.
Lifu Sun, Yuting Liu, Jingbo Zhang, Takuji Kawamura, Junjun Li, Li Liu, Shigeru Miyagawa   +6 more
wiley   +1 more source