Results 1 to 10 of about 11,081 (214)

Orlistat ameliorates lipid dysmetabolism in high-fat diet-induced mice via gut microbiota modulation

Frontiers in Microbiology
Orlistat reduces obesity by inhibiting gastrointestinal lipases, thereby blocking the absorption and accumulation of triglycerides in the intestine. It has been shown to improve lipid metabolism and alter intestinal microbial communities in animals and ...
Chengyan Huang, Yuanhui He, Ping Chai, Zongxin Liu, Sirui Su, Yanhui Zhang, Yuelan Luo, Shuiping Fu   +7 more
doaj   +1 more source

36 year old man presenting with pancreatitis and a history of recent commencement of orlistat case report

Nutrition Journal, 2006
Background Orlistat is an anti-obesity drug licensed in the United Kingdom for 7 years. We present a case of a patient who developed pancreatitis four days after commencing orlistat.
Thomas Matthew, Napier Sarah
doaj   +1 more source

Effect of orlistat on cardiovascular disease risk in obese adults

, 2005
Aim: The aim of this study is to compare the effect of orlistat vs. placebo on the predicted 10-year cardiovascular disease (CVD) risk in obese people with one or more cardiovascular risk factors treated for 12 months, in conjunction with a fat-reduced ...
J. Proietto, I. D. Caterson, Hooper, M., D. Carey, B. A. Swinburn, Carey, David, Strauss, Boyd J., B. J. Strauss, Swinburn, B. A., Carey, D., Sullivan, D., S. Marks, Sullivan, Derek, Hills, Andrew P., Hooper, Michael, Proietto, J., Welborn, Timothy A., A. P. Hills, M. Hooper, T. A. Welborn, Hills, A. P., Caterson, I. D., Marks, S., Proietto, Joseph, Caterson, Ian D., Swinburn, Boyd A., Strauss, B. J., D. Sullivan, Welborn, T. A.   +28 more
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ANALISIS EFEKTIVITAS ORLISTAT TERHADAP PENURUNAN BERAT BADAN PADA PENDERITA OBESITAS [PDF]

, 2021
Backoground : Obesity is accumulation of excess fat due to an imbalance of energy intake with the energy use for a long time. Indonesia is a country with a relatively high number of obese sufferers, both in adults, adolescents and children.
Rosyidah, Devi Usdiana, Nugroho, Hafid Adi   +1 more
core  

A comparative study of the efficacy and safety of the original and generic orlistat in obese patients in the PROFIL register

Рациональная фармакотерапия в кардиологии, 2016
Aim. To study the efficacy and safety of generic orlistat in comparison with the original drug in obese patients.Material and methods. Patients with obesity degree 1-3 (n=60; 11.7% men and 88.3% women) were included into the open comparative randomized ...
A. V. Zakharova, S. N. Tolpygina, V. P. Voronina, S. Yu. Martsevich   +3 more
doaj   +1 more source

Efficacy and safety of orlistat in male patients with overweight/obesity and hyperuricemia: results of a randomized, double-blind, placebo-controlled trial

Lipids in Health and Disease
Background Obesity is associated with elevated serum uric acid (SUA) levels and frequent gout flares. Losing weight can reduce the SUA level and gout flares.
Shuang Liu, Xiaojing Lin, Minghao Tao, Qi Chen, Hang Sun, Yali Han, Shaoling Yang, Yining Gao, Shen Qu, Haibing Chen   +9 more
doaj   +1 more source

Beneficial effects of training at the anaerobic threshold in addition to pharmacotherapy on weight loss, body composition, and exercise performance in women with obesity

Patient Preference and Adherence, 2015
Oguz Ozcelik,1 Yusuf Ozkan,2 Sermin Algul,1 Ramis Colak2,3 1Department of Physiology, 2Department of Endocrinology and Metabolic Disease, Faculty of Medicine, Firat University, Elazig, 3Department of Endocrinology and Metabolic Disease, Faculty of ...
Ozcelik O, Ozkan Y, Algul S, Colak R
doaj  

Investigating the Hepatic Response to Orlistat and White Tea in Rats on a High-Fat Diet

Life
High-fat diets have detrimental health impacts that increase the likelihood of developing obesity and metabolic syndrome. This study aimed to examine the potential antioxidant and anti-inflammatory effects of orlistat and white tea in rats fed a high-fat
Serpil Ciftel, Aleksandra Klisic, Enver Ciftel, Tolga Mercantepe, Adnan Yilmaz, Sedat Ciftel, Esra Pinarbas, Merve Nur Toraman, Filiz Mercantepe   +8 more
doaj   +1 more source

Orlistat facilitates immunotherapy via AKT-FOXO3a-FOXM1-mediated PD-L1 suppression

Journal for ImmunoTherapy of Cancer
Background The immunotherapy targeting cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) and programmed cell death ligand-1 (PD-L1) has achieved significant breakthroughs, but further improvements are still needed in cancer treatment.Methods We ...
Jie Li, Shiming Yang, Liting Wang, Xiaoyan Zhao, Changjiang Hu, Qingyun Tang, Lianhua Zhang, Shuo Zeng, Qiyu Bao, Weichao Hu, Lijiao He, Guiping Huang, Yunyi Liu   +12 more
doaj   +1 more source

Obesity management: Update on orlistat

, 2008
Belinda S Drew, Andrew F Dixon, John B DixonCentre for Obesity Research and Education, Monash University, Melbourne, AustraliaAbstract: Over the past 20 years obesity has become a worldwide concern of frightening proportion. The World Health Organization
Andrew F Dixon, John B Dixon, Belinda S Drew   +2 more
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