Results 31 to 40 of about 11,081 (214)

Unplanned medication discontinuation as a potential pharmacovigilance signal : a nested young person cohort study [PDF]

, 2014
Because of relatively small treatment numbers together with low adverse drug reaction (ADR) reporting rates the timely identification of ADRs affecting children and young people is problematic.
Marion Bennie, Helms, Peter John, Angela Peichen Sun, Kirby, Bradley, James Stuart McLay, Black, Corri, Bennie, Marion, Bradley Kirby, Sun, Angela Peichen, Corri Black, Peter John Helms, McLay, James Stuart   +11 more
core   +1 more source

Atorvastatin versus tetrahydrolipstatin in male patients with dyslipidemia: A systematic review and meta-analysis [PDF]

Journal of Pharmacy & Pharmacognosy Research
Context: Atorvastatin is typically used in the treatment of dyslipidemia. However, the interest in using anti-obesity medications such as orlistat has grown rapidly as obesity is one of the variables associated with dyslipidemia.
Nur Aini Hasan, Viskasari Pintoko Kalanjati, Kusuma Eko Purwantari, Abdurachman Abdurachman, Muhammad Miftahussurur   +4 more
doaj   +1 more source

Toxic Effects of Orlistat and Green Tea Extract on Testes of Adult Albino Rats:(Comparative Study) [PDF]

Zagazig Journal of Forensic Medicine and Toxicology, 2022
Background: Obesity is a serious medical health problem in the world. Orlistat drug and green tea herb have an important anti-obesity effect. Aim of the work: This study evaluated the chronic toxic effects of orlistat and green tea extract on testes of ...
Laila Sabik, Doaa Metwally, Eman Mohamed, Yara Elfakharany   +3 more
doaj   +1 more source

Histological and Biochemical Evaluation of Vitamin C’s Protective Role Against Orlistat-Induced Oxidative Stress and Inflammation in Rat Salivary Glands [PDF]

Alexandria Dental Journal
Background: Orlistat is lipophilic drug used for obesity treatment. Vitamin C is soluble in water with antioxidant qualities, reducing oxidative stress in salivary glands.Objective: To evaluate the protective effects of Vitamin C on the salivary glands ...
Eman M. Salem, Omnia M. Abdelfatah, Shrouk Mahmoud, Ghadir Elnawawy, Hagar S. Gharib   +4 more
doaj   +1 more source

Elevated endotoxin levels in non-alcoholic fatty liver disease [PDF]

, 2010
Background: Emerging data indicate that gut-derived endotoxin may contribute to low-grade systemic inflammation in insulin resistant states. This study aimed to examine the importance of serum endotoxin and inflammatory markers in non-alcoholic fatty ...
Ashour, E., Steven J Creely, Youssef-Elabd, E., Youssef-Elabd, Elham M., Harte, A., Abdalla, M., Creely, S., Ashour Esmat, da Silva, Nancy F., McTernan Philip G, Mohga S Abdalla, Day, C.P., Day, Christopher Paul, Billyard, T., Burt, Alastair D., Burt Alastair D, Philip G McTernan, Kumar, S., Elham M Youssef-Elabd, da Silva, N.F., Alison L Harte, Burt, A.D., Nancy F da Silva, Amin, Ashraf I., Tripathi, Gyanendra, Sharada, H., Burt, A., McTernan, P. G., Billyard, Thomas, da Silva, N., Harte, A.L., Day Christopher P, Youssef-Elabd Elham M, Tripathi Gyanendra, Alastair D Burt, Sharada, Hayat M., Hayat M Sharada, Kumar Sudhesh, Abdalla Mohga S, Sharada, H.M., Day, C., Abdalla, Mohga S., Sudhesh Kumar, Creely, S.J., McGee Kirsty C, Esmat Ashour, McTernan, P., Abdalla, M.S., Tripathi, G., McGee, K.C., Youssef-Elabd, E.M., Kirsty C McGee, Christopher P Day, Ashour, Esmat, McGee, K., Billyard Thomas, Gyanendra Tripathi, Thomas Billyard, Kumar, Sudhesh, Amin Ashraf I, Amin, A., da Silva Nancy F, Harte, A. L., Ashraf I Amin, McTernan, P.G., Creely, Steven J., McGee, K. C., Harte Alison L, Creely Steven J, Sharada Hayat M, Amin, A.I.   +70 more
core   +1 more source

Acute Oxalate Nephropathy Associated with Orlistat: A Case Report with a Review of the Literature

Case Reports in Nephrology, 2013
Orlistat is a gastrointestinal lipase inhibitor used for weight reduction in obese individuals. Enteric hyperoxaluria caused by orlistat leads to oxalate absorption. Acute oxalate nephropathy is a rare complication of treatment with orlistat.
Dhara Chaudhari, Conchitina Crisostomo, Charles Ganote, George Youngberg   +3 more
doaj   +1 more source

Effect of orlistat on liver fat content in patients with nonalcoholic fatty liver disease with obesity: assessment using magnetic resonance imaging-derived proton density fat fraction

Therapeutic Advances in Gastroenterology, 2019
Background: The liver effect of orlistat as a weight control treatment in patients with nonalcoholic fatty liver disease (NAFLD) with obesity remains undetermined.
Junzhao Ye, Yanqin Wu, Fuxi Li, Tingfeng Wu, Congxiang Shao, Yansong Lin, Wei Wang, Shiting Feng, Bihui Zhong   +8 more
doaj   +1 more source

Effect of orlistat and aquatic extract of Rosmarinus officinalis leaves in histopathological changes in kidney of albino rat [PDF]

Iraqi Journal of Veterinary Sciences, 2022
This study investigated the effects of orlistat and rosemary extract on kidney tissue when combined with a high-fat diet, as well as the association between these treatments and body weight, blood lipid profile, and oxidative stress status in male rats ...
Alya A. Al-Safo, Liqaa H. AlDulaimi
doaj   +1 more source

Orlistat in polycystic ovarian syndrome reduces weight with improvement in lipid profile and pregnancy rates

Journal of Human Reproductive Sciences, 2014
Background: The effects of exercise, metformin, and orlistat on anthropometric parameters, lipid profile, endocrine parameters, and ovulation in polycystic ovarian syndrome (PCOS) women were compared.
Pratap Kumar, Shweta Arora
doaj   +1 more source

Effect of Allium sativum extract in combination -with orlistat on insulin resistance and disrupted metabolic hormones in high fat diet induced obese rats

Scientific African, 2021
Obesity has increased in epidemic proportions globally and the current antiobesity drugs have treatment limitations which further reduce treatment benefits.
Ogunyemi Bukola Caroline, Osaretin A.T. Ebuehi, Oshanupin Adeola Cecilia, Ogunyemi Adewale Kayode   +3 more
doaj   +1 more source