Results 51 to 60 of about 8,884 (175)

Investigating the Hepatic Response to Orlistat and White Tea in Rats on a High-Fat Diet

Life
High-fat diets have detrimental health impacts that increase the likelihood of developing obesity and metabolic syndrome. This study aimed to examine the potential antioxidant and anti-inflammatory effects of orlistat and white tea in rats fed a high-fat
Serpil Ciftel, Aleksandra Klisic, Enver Ciftel, Tolga Mercantepe, Adnan Yilmaz, Sedat Ciftel, Esra Pinarbas, Merve Nur Toraman, Filiz Mercantepe   +8 more
doaj   +1 more source

The Effect of Behavioral Sleep Interventions on Measures of Obesity, Dietary Intake and Physical Activity in Adults With Poor Sleep Health: A Systematic Review, Meta‐Analysis and Meta‐Regression Analysis

Obesity Reviews, EarlyView.
ABSTRACT Background As poor sleep negatively impacts on adiposity, there is interest in examining whether improving sleep can improve adiposity markers. We reviewed studies aimed at improving sleep using (1) cognitive behavioral therapy for insomnia (CBT‐I) and/or sleep hygiene and (2) sleep extension on adiposity markers, dietary intake, and physical ...
Samiul A. Mostafa, Pushpa Singh, Feaz Babwah, Wasim Hanif, George Balanos, Krishnarajah Nirantharakumar, Jason G. Ellis, Abd A. Tahrani   +7 more
wiley   +1 more source

National and International Clinical Guidelines for the Management of Obesity in Adults: A Systematic Review

Obesity Reviews, EarlyView.
ABSTRACT Obesity is a leading risk factor for premature morbidity and mortality, and an increasing public health challenge. This review aimed to systematically identify and appraise national and international clinical guidelines for the management of obesity in adults.
Paul Doody, Ruth Martin, Barrie Tyner, Marie Carrigan, Celine Larkin, Michelle O'Neill, Susan M. Smith, Máirín Ryan   +7 more
wiley   +1 more source

Advances in Chitosan Nanoparticles: A Comprehensive Review of Properties, Synthesis, Characterization, Multidisciplinary Applications, and Future Perspectives

Journal of Applied Polymer Science, Volume 143, Issue 33, September 5, 2026.
This review highlights the synthesis of chitosan nanoparticles from natural sources, the thorough characterization of them, and use of microscopic and spectroscopic methods. It emphasizes that it has some indispensable properties such as being non‐toxic, antimicrobial, and capable of controlled drug release.
Mariam Sohail Mansoor, Nayab Raza, Furqana Bibi, Madiha Mumtaz, Asif Abbas, Farasat Haider, Basit Ali   +6 more
wiley   +1 more source

Kiwifruit Seed Polyphenols Ameliorate High‐Fat‐Induced Obese Mice via Inhibition of Inflammation and Regulation of Gut Microbiota Balance

Food Frontiers, Volume 7, Issue 5, September 2026.
Kiwifruit seed polyphenols (KSP) alleviate high‐fat diet‐induced obesity and metabolic dysfunction in mice by reducing body weight gain, adiposity, hepatic steatosis, and insulin resistance. KSP also suppresses inflammation, improves lipid metabolism, and reshapes gut microbiota composition, restoring short‐chain fatty acid production, thereby ...
Qingqing Liu, Jianxin Huang, Jinyue Xu, Qi Zhang, Ying Zhang, Haixia Yang, Wei Cao, Jianjun Deng   +7 more
wiley   +1 more source

Orlistat facilitates immunotherapy via AKT-FOXO3a-FOXM1-mediated PD-L1 suppression

Journal for ImmunoTherapy of Cancer
Background The immunotherapy targeting cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) and programmed cell death ligand-1 (PD-L1) has achieved significant breakthroughs, but further improvements are still needed in cancer treatment.Methods We ...
Jie Li, Shiming Yang, Liting Wang, Xiaoyan Zhao, Changjiang Hu, Qingyun Tang, Lianhua Zhang, Shuo Zeng, Qiyu Bao, Weichao Hu, Lijiao He, Guiping Huang, Yunyi Liu   +12 more
doaj   +1 more source

Effect of orlistat on obese women with polycystic ovary syndrome

Journal of Bio-X Research, 2018
. Polycystic ovary syndrome (PCOS) is a common gynecological endocrine syndrome characterized by metabolic abnormality and reproductive dysfunction, including ovulation abnormality, hyperandrogenism and polycystic ovarian manifestations.
Qi Jiang, Yuhua Shi
doaj   +1 more source

Molecular Mechanisms of Food Bioactive Constituents in the Management of Obesity and Hypertension: A Critical Review

Phytochemicals in Food and Medicine, Volume 1, Issue 3, September 2026.
Obesity and hypertension co‐exist and share molecular mechanisms in terms of dietary therapy, modulated by food bioactive constituents. ABSTRACT Obesity and hypertension are among the most pressing global public health challenges. They frequently co‐exist, with obesity‐related hypertension accounting for an estimated 75% of the hypertension burden ...
Samuel Oluwasegun Maccarthy, Emmanuel Anyachukwu Irondi, Abdulazeez Olamilekan Elemosho, Emmanuel Oladipo Ajani   +3 more
wiley   +1 more source

Cardiovascular Outcomes in a SELECT‐Like Obesity Cohort: Real‐World Insights From the Swedish AROS Database

Diabetes, Obesity and Metabolism, Volume 28, Issue 9, Page 8057-8071, September 2026.
ABSTRACT Background In the SELECT trial, semaglutide reduced major adverse cardiovascular outcomes (MACE) in individuals with overweight or obesity and established cardiovascular disease (CVD) but without diabetes. However, real‐world cardiovascular event rates in comparable populations remain uncharacterised.
Viveca Ritsinger, Josefine Fagerström, Håkan Nero, Thomas Cars, Maria K. Svensson, Anna Norhammar   +5 more
wiley   +1 more source

Effects of a novel weight-loss combination product containing orlistat and resveratrol on obesity: A multicenter randomized controlled study (EC-FIT)

Endocrine and Metabolic Science
Background: Orlistat, a weight loss medication, is often less effective due to poor adherence to the dietary and exercise recommendations. However, its effectiveness is often compromised by poor adherence to recommended lifestyle changes and side effects
Khin Maung Win, Tint Swe Latt, Aung Hlaing Bwa, Khin Maung Aye, Kyaw Soe Tun, Hardik Gandhi   +5 more
doaj   +1 more source