Hepatorenal and cerebellar anti-toxic effects of curcumin against orlistat associated toxicity in obese male albino rats [PDF]
Egyptian Journal of Cancer and Biomedical Research, 2022 Background: Orlistat is one of the common medicines in treating overweight, and its use may cause several side effects. Curcumin, a yellow phenolic compound isolated from Curcuma longa's rhizome, possesses several pharmaceutical effects due to its ...
Eman Kandil, Samah Arisha
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The effects of orlistat on metabolic parameters and other cardiovascular risk factors
Diabetes and Metabolism, 2005 Orlistat is an antiobesity drug with a well documented efficacy in weight reduction and weight maintenance. Weight reduction with orlistat has been associated with a favourable effect on obesity-related cardiovascular risk factors.
D N Kiortsis +2 more
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Folia Medica Indonesiana, 2022 Hightlight: • The effect of orlistat on glycemic control and weight loss in overweight or obese type 2 diabetes mellitus patients was determined • HbA1c and FPG level in overweight and obese type 2 diabetes mellitus patient can improved by orlistat as
Abu Rizal Dwikatmono Johan +6 more
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Myelopoietic efficacy of orlistat in murine hosts bearing T cell lymphoma: implication in macrophage differentiation and activation. [PDF]
PLoS ONE, 2013 Orlistat, an inhibitor of fatty acid synthase (FASN), acts as an antitumor agent by blocking de novo fatty acid synthesis of tumor cells. Although, myelopoiesis also depends on de novo fatty acid synthesis, the effect of orlistat on differentiation of ...
Shiva Kant +2 more
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Evaluating the Effect of Orlistat Administration on Depressive Behavior in Mice Following Inducing Depression by Water Avoidance Stress Model [PDF]
Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2023 Introduction: The weight-loss drugs can induce depression. Orlistat is one of the common weight-loss drugs, but preclinical studies about its effect on mood have not been performed.
Nazanin Behrooz, Azadeh Mesripour
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ASSESSING THE EFFECTS OF ORLISTAT AS AN ANTI-OBESITY DRUG IN HIGH FAT DIET INDUCED OBESITY IN MALE RATS [PDF]
Bulletin of Pharmaceutical Sciences. Assiut University, 2021 The present work was designed to evaluate the effectiveness of the orlistat drug on some hormones and biochemical parameters in male rats received a high fat diet (HFD).
Omnia Abdel-Rahman, Enas Abdel-Baky
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The Possible Protective Role of Pumpkin Seed Oil in Ameliorating Tongue Mucosal Damage Induced by Orlistat in Adult Male Albino Rats: A Light and Scanning Electron Microscopic Study [PDF]
The Egyptian Journal of Histology, 2020 Background: Orlistat is an effective anti-obesity drug by reducing fat absorption. The oral cavity and its associated structures are target organs for many abnormalities that develop from orlistat.
Amira Kassab +2 more
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Nephrotoxicity associated with Orlistat in normal and obese female rats [PDF]
Journal of Bioscience and Applied Research, 2018 Obesity is a global health concern associated with high morbidity and mortality. Therapeutic strategies include synthetic drugs and surgery, which may entail high costs and serious complications. Orlistat is a pancreatic lipase inhibitor licensed for the
Ehab Tousson +3 more
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Pharmaceutics, 2020 The aim of this work was to develop an amorphous orlistat-loaded mesoporus silica formulation using the melt-amorphisation by supercritical fluid (MA-SCF) and to investigate the effects of pressure and temperature on the pharmaceutical properties of the ...
Heejun Park +7 more
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Foods, 2023 Background: Black garlic, also known as fermented garlic, is a useful food that may have therapeutic benefits. The aim of this study was to analyze the impact of fermented garlic and orlistat therapy on obese rats. Methods: A total of 40 male albino rats
Mavra Javed +3 more
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