Results 21 to 30 of about 12,566 (192)

Pragmatic study of orlistat 60 mg on abdominal obesity [PDF]

, 2011
Background/Objectives: It is well established that combining a reduced calorie, low-fat diet with the lipase inhibitor orlistat results in significantly greater weight loss than placebo plus diet.
Frost, G.S., Matthews, P.M., S M Schwartz, Delafont, B., J D Beaver, E L Thomas, G Frost, Mishra, R.G., Gambarota, G., J D Bell, R Newbould, Thomas, E.L., P M Matthews, Bell, J.D., A W Rao, A Makwana, Berk, E.S., G Gambarota, Makwana, A., R G Mishra, B Delafont, E S Berk, Beaver, J.D., Schwartz, S.M., Newbould, R., Rao, A.W.   +25 more
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Lipase inhibition attenuates the acute inhibitory effects of oral fat on food intake in healthy subjects [PDF]

, 2003
The lipase inhibitor, orlistat, is used in the treatment of obesity and reduces fat absorption by about 30%. However, the mean weight loss induced by orlistat is less than expected for the degree of fat malabsorption.
O'Donovan, D., Wishart, J., Horowitz, M., Feinle-Bisset, C.   +3 more
core   +1 more source

Atorvastatin versus tetrahydrolipstatin in male patients with dyslipidemia: A systematic review and meta-analysis [PDF]

Journal of Pharmacy & Pharmacognosy Research
Context: Atorvastatin is typically used in the treatment of dyslipidemia. However, the interest in using anti-obesity medications such as orlistat has grown rapidly as obesity is one of the variables associated with dyslipidemia.
Nur Aini Hasan, Viskasari Pintoko Kalanjati, Kusuma Eko Purwantari, Abdurachman Abdurachman, Muhammad Miftahussurur   +4 more
doaj   +1 more source

Acute Oxalate Nephropathy Associated with Orlistat: A Case Report with a Review of the Literature

Case Reports in Nephrology, 2013
Orlistat is a gastrointestinal lipase inhibitor used for weight reduction in obese individuals. Enteric hyperoxaluria caused by orlistat leads to oxalate absorption. Acute oxalate nephropathy is a rare complication of treatment with orlistat.
Dhara Chaudhari, Conchitina Crisostomo, Charles Ganote, George Youngberg   +3 more
doaj   +1 more source

Toxic Effects of Orlistat and Green Tea Extract on Testes of Adult Albino Rats:(Comparative Study) [PDF]

Zagazig Journal of Forensic Medicine and Toxicology, 2022
Background: Obesity is a serious medical health problem in the world. Orlistat drug and green tea herb have an important anti-obesity effect. Aim of the work: This study evaluated the chronic toxic effects of orlistat and green tea extract on testes of ...
Laila Sabik, Doaa Metwally, Eman Mohamed, Yara Elfakharany   +3 more
doaj   +1 more source

Acute Pancreatitis Following Orlistat Therapy: Report of Two Cases [PDF]

, 2015
Context Orlistat is a pancreatic lipase inhibitor licensed for the treatment of obesity. As obesity rates increase and non-prescription dispensing of orlistat increases, an awareness of its adverse effects is of crucial importance as complications arise ...
Mahmud, Sajid, Sajid Mahmud, Faheem Asem Ahmad, Ahmad, Faheem Asem   +3 more
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Histological and Biochemical Evaluation of Vitamin C’s Protective Role Against Orlistat-Induced Oxidative Stress and Inflammation in Rat Salivary Glands [PDF]

Alexandria Dental Journal
Background: Orlistat is lipophilic drug used for obesity treatment. Vitamin C is soluble in water with antioxidant qualities, reducing oxidative stress in salivary glands.Objective: To evaluate the protective effects of Vitamin C on the salivary glands ...
Eman M. Salem, Omnia M. Abdelfatah, Shrouk Mahmoud, Ghadir Elnawawy, Hagar S. Gharib   +4 more
doaj   +1 more source

Elevated endotoxin levels in non-alcoholic fatty liver disease [PDF]

, 2010
Background: Emerging data indicate that gut-derived endotoxin may contribute to low-grade systemic inflammation in insulin resistant states. This study aimed to examine the importance of serum endotoxin and inflammatory markers in non-alcoholic fatty ...
Ashour, E., Steven J Creely, Youssef-Elabd, E., Youssef-Elabd, Elham M., Harte, A., Abdalla, M., Creely, S., Ashour Esmat, da Silva, Nancy F., McTernan Philip G, Mohga S Abdalla, Day, C.P., Day, Christopher Paul, Billyard, T., Burt, Alastair D., Burt Alastair D, Philip G McTernan, Kumar, S., Elham M Youssef-Elabd, da Silva, N.F., Alison L Harte, Burt, A.D., Nancy F da Silva, Amin, Ashraf I., Tripathi, Gyanendra, Sharada, H., Burt, A., McTernan, P. G., Billyard, Thomas, da Silva, N., Harte, A.L., Day Christopher P, Youssef-Elabd Elham M, Tripathi Gyanendra, Alastair D Burt, Sharada, Hayat M., Hayat M Sharada, Kumar Sudhesh, Abdalla Mohga S, Sharada, H.M., Day, C., Abdalla, Mohga S., Sudhesh Kumar, Creely, S.J., McGee Kirsty C, Esmat Ashour, McTernan, P., Abdalla, M.S., Tripathi, G., McGee, K.C., Youssef-Elabd, E.M., Kirsty C McGee, Christopher P Day, Ashour, Esmat, McGee, K., Billyard Thomas, Gyanendra Tripathi, Thomas Billyard, Kumar, Sudhesh, Amin Ashraf I, Amin, A., da Silva Nancy F, Harte, A. L., Ashraf I Amin, McTernan, P.G., Creely, Steven J., McGee, K. C., Harte Alison L, Creely Steven J, Sharada Hayat M, Amin, A.I.   +70 more
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Effect of orlistat and aquatic extract of Rosmarinus officinalis leaves in histopathological changes in kidney of albino rat [PDF]

Iraqi Journal of Veterinary Sciences, 2022
This study investigated the effects of orlistat and rosemary extract on kidney tissue when combined with a high-fat diet, as well as the association between these treatments and body weight, blood lipid profile, and oxidative stress status in male rats ...
Alya A. Al-Safo, Liqaa H. AlDulaimi
doaj   +1 more source

Effect of orlistat on liver fat content in patients with nonalcoholic fatty liver disease with obesity: assessment using magnetic resonance imaging-derived proton density fat fraction

Therapeutic Advances in Gastroenterology, 2019
Background: The liver effect of orlistat as a weight control treatment in patients with nonalcoholic fatty liver disease (NAFLD) with obesity remains undetermined.
Junzhao Ye, Yanqin Wu, Fuxi Li, Tingfeng Wu, Congxiang Shao, Yansong Lin, Wei Wang, Shiting Feng, Bihui Zhong   +8 more
doaj   +1 more source