Results 11 to 20 of about 11,081 (214)
Reactions Weekly, 2009 ZusammenfassungOrlistat (Tetrahydrolipstatin) ist der erste im Darm (peripher) nachgewiesen wirksame, pharmakologisch effektive Fettresorptionshemmer. Orlistat hemmt die intestinale Triglyzeridlipase und senkt so die gastrointestinale Fettspaltung dosisabhängig um bis zu etwa 35 Prozent.
H. Toplak
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Effect of anti-obesity drug orlistat (Xenical™) on liver and kidney function in male rats fed a high-fat diet [version 2; peer review: 1 approved, 2 approved with reservations] [PDF]
F1000ResearchBackground HFDs have adverse effects on metabolic health, which puts individuals at risk of obesity and liver and kidney dysfunction. Orlistat is an antihypertensive agent against obesity that prevents the absorption of dietary fats, although its impact ...
Asmaa M. Neamah +4 more
doaj +2 more sources
Orlistat : Viktminskning med orlistat
, 2021 Introduktion: Fetma är en sjukdom då kroppen har lagrat för mycket fett. Det kan bero på olika orsaker och en vanlig orsak är att kroppens energiintag är större än kroppens energiförbrukning och då kan överskottsenergin lagras som fett.
Hajo, Sliva
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An Unexpected Result of Obesity Treatment: Orlistat-Related Acute Pancreatitis
Case Reports in Gastroenterology, 2015 Orlistat is a pancreatic lipase inhibitor which is used to treat obesity. Due to the increasing prevalence of obesity, orlistat use is thought to rise progressively. We report an interesting case caused by orlistat use caught in the early stages of acute
Murat Kose +6 more
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The Application of Quantitative 1H-NMR for the Determination of Orlistat in Tablets
Molecules, 2017 A quantitative nuclear magnetic resonance (qNMR) method to measure the content of Orlistat in tablets was studied and found to be efficient, accurate, reliable, and simple.
Hongyue Liu, Yinghong Wang
exaly +3 more sources
Effect of orlistat on obese women with polycystic ovary syndrome
Journal of Bio-X Research, 2018 . Polycystic ovary syndrome (PCOS) is a common gynecological endocrine syndrome characterized by metabolic abnormality and reproductive dysfunction, including ovulation abnormality, hyperandrogenism and polycystic ovarian manifestations.
Qi Jiang, Yuhua Shi
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Evaluation of efficacy and safety of orlistat in obese patients
Indian Journal of Endocrinology and Metabolism, 2011 Context: Rapidly rising prevalence of obesity is alarming. Obesity predisposes to co-morbidities like hypertension, type 2 diabetes mellitus, dyslipidemias, thus substantially rising healthcare expenditure. Lifestyle modifications alone have very limited
Suyog S Jain +5 more
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Therapeutics and Clinical Risk Management, 2017 Rashid Ali Khan,1 Prem Kapur,2 Abhinav Jain,3 Farrukh Farah,4 Uma Bhandari11Department of Pharmacology, Faculty of Pharmacy, 2Department of Medicine, 3Department of Radiology, 4Department of Paramedical Sciences, Hamdard Institute of Medical Sciences ...
Ali Khan R +4 more
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Mechanism of Orlistat Hydrolysis by the Thioesterase of Human Fatty Acid Synthase
ACS Catalysis, 2014 Fatty acid synthase (FASN), the sole protein capable of de novo synthesis of free fatty acids, is overexpressed in a wide variety of human cancers and is associated with poor prognosis and aggressiveness of these cancers.
Jian-Ting Zhang, Jing-Yuan Liu
exaly +2 more sources
Orlistat-loaded solid SNEDDS for the enhanced solubility, dissolution, and in vivo performance
International Journal of Nanomedicine, 2018 Dae Hun Kim,1,* Jae Yeol Kim,1,* Rae Man Kim,1 Pooja Maharjan,1 Yu-Geun Ji,2 Dong-Jin Jang,3 Kyoung Ah Min,1 Tae-Sung Koo,2 Kwan Hyung Cho1 1Department of Pharmacy, Inje Institute of Pharmaceutical Sciences and Research, Inje University, Gimhae ...
Kim DH +8 more
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