Results 11 to 20 of about 8,884 (175)

Weight‐Lowering Drugs and Natural Female Fertility—A Systematic Review and Meta‐Analysis [PDF]

Clinical Obesity, Volume 16, Issue 4, August 2026.
ABSTRACT Overweight and obesity are global health concerns linked to impaired female fertility. Weight‐lowering drugs are an alternative for achieving weight loss; however, their effect on natural female fertility is unclear. A systematic review and meta‐analysis were conducted to summarise the literature on the effects of weight‐lowering drugs on ...
Shaikha Jabor Alnaimi, Dana Muwafag Alsugeir, Li Wei, Kirsten Harvey, Ruth Brauer   +4 more
wiley   +2 more sources

Effect of anti-obesity drug orlistat (Xenical™) on liver and kidney function in male rats fed a high-fat diet [version 2; peer review: 1 approved, 2 approved with reservations] [PDF]

F1000Research
Background HFDs have adverse effects on metabolic health, which puts individuals at risk of obesity and liver and kidney dysfunction. Orlistat is an antihypertensive agent against obesity that prevents the absorption of dietary fats, although its impact ...
Asmaa M. Neamah, Ahmed S. Jarad, Mokhtar I Yousef, Mohammed Y.I. Al-Hamadani, Sura M. Alkadhimy   +4 more
doaj   +2 more sources

Atorvastatin versus tetrahydrolipstatin in male patients with dyslipidemia: A systematic review and meta-analysis [PDF]

Journal of Pharmacy & Pharmacognosy Research
Context: Atorvastatin is typically used in the treatment of dyslipidemia. However, the interest in using anti-obesity medications such as orlistat has grown rapidly as obesity is one of the variables associated with dyslipidemia.
Nur Aini Hasan, Viskasari Pintoko Kalanjati, Kusuma Eko Purwantari, Abdurachman Abdurachman, Muhammad Miftahussurur   +4 more
doaj   +1 more source

Toxic Effects of Orlistat and Green Tea Extract on Testes of Adult Albino Rats:(Comparative Study) [PDF]

Zagazig Journal of Forensic Medicine and Toxicology, 2022
Background: Obesity is a serious medical health problem in the world. Orlistat drug and green tea herb have an important anti-obesity effect. Aim of the work: This study evaluated the chronic toxic effects of orlistat and green tea extract on testes of ...
Laila Sabik, Doaa Metwally, Eman Mohamed, Yara Elfakharany   +3 more
doaj   +1 more source

Histological and Biochemical Evaluation of Vitamin C’s Protective Role Against Orlistat-Induced Oxidative Stress and Inflammation in Rat Salivary Glands [PDF]

Alexandria Dental Journal
Background: Orlistat is lipophilic drug used for obesity treatment. Vitamin C is soluble in water with antioxidant qualities, reducing oxidative stress in salivary glands.Objective: To evaluate the protective effects of Vitamin C on the salivary glands ...
Eman M. Salem, Omnia M. Abdelfatah, Shrouk Mahmoud, Ghadir Elnawawy, Hagar S. Gharib   +4 more
doaj   +1 more source

Acute Oxalate Nephropathy Associated with Orlistat: A Case Report with a Review of the Literature

Case Reports in Nephrology, 2013
Orlistat is a gastrointestinal lipase inhibitor used for weight reduction in obese individuals. Enteric hyperoxaluria caused by orlistat leads to oxalate absorption. Acute oxalate nephropathy is a rare complication of treatment with orlistat.
Dhara Chaudhari, Conchitina Crisostomo, Charles Ganote, George Youngberg   +3 more
doaj   +1 more source

Effect of orlistat on liver fat content in patients with nonalcoholic fatty liver disease with obesity: assessment using magnetic resonance imaging-derived proton density fat fraction

Therapeutic Advances in Gastroenterology, 2019
Background: The liver effect of orlistat as a weight control treatment in patients with nonalcoholic fatty liver disease (NAFLD) with obesity remains undetermined.
Junzhao Ye, Yanqin Wu, Fuxi Li, Tingfeng Wu, Congxiang Shao, Yansong Lin, Wei Wang, Shiting Feng, Bihui Zhong   +8 more
doaj   +1 more source

Orlistat in polycystic ovarian syndrome reduces weight with improvement in lipid profile and pregnancy rates

Journal of Human Reproductive Sciences, 2014
Background: The effects of exercise, metformin, and orlistat on anthropometric parameters, lipid profile, endocrine parameters, and ovulation in polycystic ovarian syndrome (PCOS) women were compared.
Pratap Kumar, Shweta Arora
doaj   +1 more source

Effect of orlistat and aquatic extract of Rosmarinus officinalis leaves in histopathological changes in kidney of albino rat [PDF]

Iraqi Journal of Veterinary Sciences, 2022
This study investigated the effects of orlistat and rosemary extract on kidney tissue when combined with a high-fat diet, as well as the association between these treatments and body weight, blood lipid profile, and oxidative stress status in male rats ...
Alya A. Al-Safo, Liqaa H. AlDulaimi
doaj   +1 more source

orlistat improves release of gut hormones increasing satiety in obese women

Ожирение и метаболизм, 2014
Orlistat, which reduces fat absorption by inhibiting intestinal lipase is a registered drug for obesity pharmacotherapy. Meta-analyzes indicate various positive metabolic effects of orlistat, including improvements in glucose and lipid metabolism ...
Teona Albertovna Shvangiradze
doaj   +1 more source