Anti-obesity activity of Cymbopogon citratus (lemongrass): A systematic review [PDF]
Journal of Pharmacy & Pharmacognosy ResearchContext: Obesity represents a significant global health challenge. The limited efficacy and possible side effects of available anti-obesity agents highlight the need to find new, effective, and safe agents. Lemongrass (Cymbopogon citratus) is an aromatic
Musthika Wida Mashitah +3 more
doaj +2 more sources
A Hamster Model of Diet-Induced Obesity for Preclinical Evaluation of Anti-Obesity, Anti-Diabetic and Lipid Modulating Agents. [PDF]
PLoS ONE, 2015 Unlike rats and mice, hamsters develop hypercholesterolemia, and hypertriglyceridemia when fed a cholesterol-rich diet. Because hyperlipidemia is a hallmark of human obesity, we aimed to develop and characterize a novel diet-induced obesity (DIO) and ...
Louise S Dalbøge +6 more
doaj +2 more sources
Adipose Stromal/Stem Cell-Derived Extracellular Vesicles: Potential Next-Generation Anti-Obesity Agents. [PDF]
Int J Mol Sci, 2022 Over the last decade, several compounds have been identified for the treatment of obesity. However, due to the complexity of the disease, many pharmacological interventions have raised concerns about their efficacy and safety.
Zuccarini M +8 more
europepmc +4 more sources
Applied Biological Chemistry, 2023 Obesity is a health condition accompanied by life-threatening comorbidities; hence, there is an increasing need for anti-obesity agents. The anti-cancer effects of the leaves of Asimina triloba (pawpaw) has been reported.
Chang Jun Lee +4 more
doaj +1 more source
Insights on Dietary Polyphenols as Agents against Metabolic Disorders: Obesity as a Target Disease
Antioxidants, 2023 Obesity is a condition that leads to increased health problems associated with metabolic disorders. Synthetic drugs are available for obesity treatment, but some of these compounds have demonstrated considerable side effects that limit their use ...
Simon-Okomo Aloo +4 more
doaj +1 more source
Inquiry on a Potential Anti-Obesity Agent
The American Biology Teacher, 2023 This study introduces a practical work activity that allows students to investigate the inhibitory effects of seed extracts on pancreatic lipase activity. The activity is related to the issue of the ongoing global obesity epidemic and involves the use of materials and chemicals readily available in high school laboratories. We show how the activity can
Pat Chun Chan, Kennedy Kam Ho Chan
openaire +1 more source
Anti-inflammatory agents as modulators of the inflammation in adipose tissue: A systematic review.
PLoS ONE, 2022 Obesity is characterized by an adipose tissue mass expansion that presents a risk to health, associated with a chronic increase in circulating inflammatory mediators. Anti-inflammatory agents are an obesity alternative treatment.
Sara Sayonara da Cruz Nascimento +7 more
doaj +1 more source
Obesity and Cardiovascular Disease: The Emerging Role of Inflammation
Frontiers in Cardiovascular Medicine, 2021 Obesity is a growing public health challenge across the globe. It is associated with increased morbidity and mortality. Cardiovascular disease (CVD) is the leading cause of mortality for people with obesity.
Rana Khafagy +4 more
doaj +1 more source
Equisetin is an anti-obesity candidate through targeting 11β-HSD1
Acta Pharmaceutica Sinica B, 2022 Obesity is increasingly prevalent globally, searching for therapeutic agents acting on adipose tissue is of great importance. Equisetin (EQST), a meroterpenoid isolated from a marine sponge-derived fungus, has been reported to display antibacterial and ...
Zhenlu Xu +12 more
doaj +1 more source
Hydrolyzed Proteins and Vegetable Peptides: Anti-Inflammatory Mechanisms in Obesity and Potential Therapeutic Targets [PDF]
, 2022 Chronic low-grade inflammation is present in overweight and obesity, causing changes in several metabolic pathways. It impairs systemic functioning and positively feeds back the accumulation of more adipose tissue.
Queiroz, Jaluza Luana Carvalho de +7 more
core +1 more source