Results 11 to 20 of about 4,309,747 (310)

Marine Algae as a Potential Source for Anti-Obesity Agents [PDF]

Marine Drugs, 2016
Obesity is a major epidemic that poses a worldwide threat to human health, as it is also associated with metabolic syndrome, type 2 diabetes and cardiovascular disease. Therapeutic intervention through weight loss drugs, accompanied by diet and exercise,
Chu Wan-Loy, Phang Siew-Moi
doaj   +9 more sources

Natural anti-obesity agents [PDF]

Bulletin of Faculty of Pharmacy Cairo University, 2014
Obesity is a complex disease caused by the interaction of a myriad of genetic, dietary, lifestyle, and environmental factors, which favors a chronic positive energy balance, and leads to increased body fat mass.
Gamal A. Mohamed, Sabrin R.M. Ibrahim, Ehab S. Elkhayat, Riham Salah El Dine   +3 more
doaj   +4 more sources

Natural products as novel anti-obesity agents: insights into mechanisms of action and potential for therapeutic management [PDF]

Frontiers in Pharmacology, 2023
Obesity affects more than 10% of the adult population globally. Despite the introduction of diverse medications aimed at combating fat accumulation and obesity, a significant number of these pharmaceutical interventions are linked to substantial ...
Ummul Fathima Shaik Mohamed Sayed, Said Moshawih, Hui Poh Goh, Nurolaini Kifli, Gaurav Gupta, Gaurav Gupta, Sachin Kumar Singh, Sachin Kumar Singh, Dinesh Kumar Chellappan, Kamal Dua, Kamal Dua, Kamal Dua, Andi Hermansyah, Hooi Leng Ser, Long Chiau Ming, Long Chiau Ming, Long Chiau Ming, Bey Hing Goh, Bey Hing Goh   +18 more
doaj   +3 more sources

Recent Advances in Anti-Obesity Agents

The Korean Journal of Medicine, 2018
Obesity is a chronic disorder that is a significant risk factor for diabetes, cardiovascular diseases, malignancy, and other chronic diseases. Lifestyle modifications form the basis of most treatments for obesity, but it has become clear that such modifications alone are not enough for many obese patients.
Min Kyung Kim, Chul Sik Kim
openaire   +2 more sources

Therapeutic Potential of Anti-Obesity Drugs in Obesity-Associated Female Reproductive Dysfunction: Translating Mechanistic Evidence into Personalized Clinical Strategies [PDF]

Medicina
Obesity is a multifactorial condition that profoundly affects female reproductive health through endocrine, metabolic, and inflammatory mechanisms that disrupt the hypothalamic–pituitary–gonadal (HPG) axis. Women with obesity frequently develop menstrual
Fani-Niki Varra, Panagiotis Theodosis-Nobelos, Viktoria-Konstantina Varra, Michail Varras   +3 more
doaj   +2 more sources

Obesity and response to anti-tumor necrosis factor-α agents in patients with select immune-mediated inflammatory diseases: A systematic review and meta-analysis.

PLoS ONE, 2018
ObjectivesWe sought to evaluate the association between obesity and response to anti-tumor necrosis factor-α (TNF) agents, through a systematic review and meta-analysis.MethodsThrough a systematic search through January 24, 2017, we identified randomized
Siddharth Singh, Antonio Facciorusso, Abha G Singh, Niels Vande Casteele, Amir Zarrinpar, Larry J Prokop, Eduardo L Grunvald, Jeffrey R Curtis, William J Sandborn   +8 more
doaj   +3 more sources

Screening of Anti-Obesity Agent from Herbal Mixtures [PDF]

Molecules, 2012
Globally, one in three of the World’s adults are overweight and one in 10 is obese. By 2015, World Health Organization (WHO) estimates the number of chubby adults will balloon to 2.3 billion—Equal to the combined populations of China, Europe and the ...
Sung-Kee Jo, Uhee Jung, Changhyun Roh
doaj   +3 more sources

Adipose Stromal/Stem Cell-Derived Extracellular Vesicles: Potential Next-Generation Anti-Obesity Agents. [PDF]

Int J Mol Sci, 2022
Over the last decade, several compounds have been identified for the treatment of obesity. However, due to the complexity of the disease, many pharmacological interventions have raised concerns about their efficacy and safety.
Zuccarini M, Giuliani P, Di Liberto V, Frinchi M, Caciagli F, Caruso V, Ciccarelli R, Mudò G, Di Iorio P.   +8 more
europepmc   +2 more sources

Lipidome remodeling activities of DPA-EA in palmitic acid-stimulated HepG2 cells and the in vivo anti-obesity effect of the DPA-EA and DHA-EA mixture prepared from algae oil

Frontiers in Pharmacology, 2023
Background: The nuclear receptor Nur77 has been demonstrated to play a vital role in the inflammatory response and cellular metabolisms, and its ligands exhibit efficacy in the treatment of inflammation-related diseases (e.g., improving mouse acute lung ...
Hua Fang, Yin Cao, Jianyu Zhang, Xiumei Wang, Mengyu Li, Mengyu Li, Zhuan Hong, Zhen Wu, Meijuan Fang   +8 more
doaj   +2 more sources

Regulation of adipocyte differentiation and lipid metabolism by novel synthetic chromenes exploring anti-obesity and broader therapeutic potential

Scientific Reports
Obesity poses a significant global health challenge, necessitating the search for novel therapeutic agents to address this epidemic. Chromenes, known for their diverse bioactivities, hold promise as potential anti-obesity compounds, yet research in this ...
Kewalin Inthanon, Natthawut Wong-a-nan, Srisulak Dheeranupattana, Andres Garcia Guerra, Neal M. Davies, Chatchai Kesornpun, Sasithorn Sangher, Prasat Kittakoop   +7 more
doaj   +2 more sources