Results 31 to 40 of about 46,192 (239)

Effectiveness, tolerability and practical application of the newer generation anti-obesity medications [PDF]

, 2016
Objective: Comparison of the efficacy and tolerability of five newer anti-obesity medications to guide clinical decision making, examining bupropion–naltrexone combination, liraglutide, lorcaserin, orlistat, and phentermine–topiramate combination ...
Thomas L Schwartz, Jeffrey S MacDaniels
core   +1 more source

Caregiver Perspective of Benefits and Side Effects of Anti-Seizure Medications in CDKL5 Deficiency Disorder from an International Database. [PDF]

CNS Drugs
BACKGROUND AND OBJECTIVE: CDKL5 deficiency disorder presents as a challenging condition with early-onset refractory seizures, severe developmental delays, and a range of other neurological symptoms.
Wong K, Junaid M, Alexander S, Olson HE, Pestana-Knight EM, Rajaraman RR, Downs J, Leonard H.   +7 more
europepmc   +2 more sources

Risk factors of paradoxical reactions to anti-seizure medication in genetic generalized epilepsy [PDF]

, 2021
This study aimed at providing valid estimates for the risk of clinically relevant seizure aggravation by recommended anti-seizure medications in patients with Genetic Generalized Epilepsy (GGE).
Gesche, Joanna, Rubboli, Guido, Beier, Christoph Patrick; id_orcid, Hjalgrim, Helle, Beier, Christoph Patrick   +4 more
core   +1 more source

Role of common genetic variants for drug-resistance to specific anti-seizure medications [PDF]

, 2021
Objective: Resistance to anti-seizure medications (ASMs) presents a significant hurdle in the treatment of people with epilepsy. Genetic markers for resistance to individual ASMs could support clinicians to make better-informed choices for their patients.
Michael R Johnson (7947884), Krause, R, Bobby PC Koeleman (10490724), Epipgx Consortium,, Sanjay M Sisodiya (7947911), Mark McCormack (7947842), Krause, Roland, Kunz, WS, Holger Lerche (455372), Lerche, Holger, Caragh Stapleton (7925609), Roland Krause (4351), Cavalleri, Gianpiero, McCormack, Mark, Koeleman, BPC, Federico Zara (176248), Sander, JW, Wolking, S, Johnson, Michael R., Sisodiya, SM, Depondt, C, Stefan Wolking (5687657), Zara, F, Sills, Graeme J., Ciaran Campbell (7896956), Cavalleri, Gianpiero L., Koeleman, Bobby P. C., EpiPGX Consortium (10490732), Koeleman, Bobby B.P.C., Sisodiya, Sanjay, Josemir W Sander (6789449), Pasquale Striano (4479343), Campbell, Ciarán, Marson, Anthony G., McCormack, M, Delanty, N, Stapleton, C, Wolking, Stefan, Sander, Josemir W., Norman Delanty (7895990), Johnson, MR, Cavalleri, GL, Sills, Graeme, Graeme J Sills (7947872), Gianpiero Cavalleri (7895525), Depondt, Chantal, Wolfram S Kunz (7947893), Campbell, C, Johnson, Michael, Striano, Pasquale, Kunz, Wolfram W.S., Sisodiya, Sanjay M., Marson, Anthony Guy, Lerche, H, Marson, AG, Chantal Depondt (7947869), Delanty, Norman, Zara, Federico, Kunz, Wolfram S., Sills, GJ, Stapleton, Caragh, Anthony G Marson (7947875), Striano, P, Sander, Josemir W   +63 more
core   +4 more sources

Traditional and innovative anti-seizure medications targeting key physiopathological mechanisms. Focus on neurodevelopment and neurodegeneration

, 2023
Despite the wide range of compounds currently available to treat epilepsy, there is still no drug that directly tackles the physiopathological mechanisms underlying its development.
Ruffolo G., Palma E., Costa C., Sciaccaluga M.   +3 more
core   +1 more source

Poor Seizure Control Among Children Attending a Tertiary 8 Hospital in South Western Uganda – A Retrospective Study [Response to Letter]

International Journal of General Medicine, 2023
Jane Namusisi,1 Mark Kaddumukasa,2 Martha Sajatovic,3 Peter Kalubi1 1Department of Pediatrics and Child Health, Mbarara University of Science and Technology (MUST), Mbarara, Uganda; 2Department of Medicine, College of Health Sciences, Makerere University,
Namusisi J, Kaddumukasa M, Sajatovic M, Kalubi P   +3 more
doaj  

Meningioma Related Epilepsy- Pathophysiology, Pre/postoperative Seizures Predicators and Treatment

Frontiers in Oncology, 2022
Meningiomas are the most common primary brain tumors accounting for about 30% of all brain tumors. The vast majority of meningiomas are slow-growing and of benign histopathology rendering them curable by surgery alone.
Rasha Elbadry Ahmed, Hailiang Tang, Anthony Asemota, Lei Huang, Lei Huang, Warren Boling, Firas Bannout   +6 more
doaj   +1 more source

Poor Seizure Control Among Children Attending a Tertiary Hospital in South Western Uganda – A Retrospective Study [Letter]

International Journal of General Medicine, 2023
Selvi A Mangundap Department of Nursing, Poltekkes Kemenkes Palu, Palu, IndonesiaCorrespondence: Selvi A Mangundap, Faculty of Nursing, Poltekkes Kemenkes Palu, Thalua Konchi Street Number 09, North Palu, Palu, Center Sulawesi, Indonesia, Email selvi.541.
Mangundap SA
doaj  

Autoimmune epilepsy due to N-methyl-d-aspartate receptor antibodies in a child: a case report

Journal of Medical Case Reports, 2021
Introduction Seizures of autoimmune etiology may occur independent of or predate syndromes of encephalitis. We report a child with “pure” autoimmune epilepsy followed up for 7 years to highlight long-term effects of this epilepsy and the importance of ...
Jithangi Wanigasinghe, Thashi Chang
doaj   +1 more source

Replacement of Valproic Acid with New Anti-Seizure Medications in Idiopathic Generalized Epilepsy

, 2022
HIGHLIGHTS:   What are the main findings? Replacement of VPA with new ASMs provided the same or better seizure control. Replacement of VPA with new ASMs provided better myoclonus control.
Fujimoto, Ayataka, Okanishi, Tohru, Keishiro Sato, Tohru Okanishi, Hideo Enoki, Keisuke Hatano, Ayataka Fujimoto, Enoki, Hideo, Sato, Keishiro, Hatano, Keisuke   +9 more
core   +1 more source