Results 61 to 70 of about 130 (117)

Plant‐Produced Viral Nanoparticles Decorated with Nanobodies Against HER2 Improve Retention and Recruitment of Immune Cells in Solid Tumors

Advanced Healthcare Materials, Volume 15, Issue 18, 15 May 2026.
Potato virus X is a filamentous RNA plant virus that can be engineered into a molecular tool for cancer therapy. We produced genetically‐encoded virus‐derived nanoparticles decorated with nanobodies targeting cancer cell receptors, epidermal growth factor receptor (EGFR) and human epidermal growth factor 2 (HER2).
Enrique Lozano‐Sanchez, Miguel A. Moreno‐Gonzalez, Fernando Merwaiss, Nicole F. Steinmetz, José‐Antonio Daròs   +4 more
wiley   +1 more source

Plant Genetic Engineering: Technological Pathways, Application Scenarios, and Future Directions

Advanced Science, Volume 13, Issue 30, 28 May 2026.
This review maps the fast‐evolving landscape of plant genetic engineering, linking enabling platforms with trait‐focused applications in architecture optimization, stress resilience, yield improvement, and quality enhancement. It highlights how genome editing, transgenic strategies, and emerging multi‐gene approaches reshape breeding pipelines, while ...
Peilin Wang, Wenzhi Wang, Dongjiao Wang, Qibin Wu, Youxiong Que   +4 more
wiley   +1 more source

Virus‐Induced Gene Silencing in Calendula officinalis (Pot Marigold)

Plant Direct, Volume 10, Issue 5, May 2026.
ABSTRACT Virus‐induced gene silencing (VIGS) is a method that exploits plant antiviral defense mechanisms to downregulate endogenous genes. The technique is versatile, rapid, and widely used for functional genomics studies. Here, we report a method for VIGS in the medicinal plant, Calendula officinalis (pot marigold).
Daria Cuthbert, Connor Tansley, Melissa Salmon, Nicola Patron   +3 more
wiley   +1 more source

Synthesis and Bioactivity of Pyrazole Acyl Thiourea Derivatives

Molecules, 2012
Sixteen novel pyrazole acyl thiourea derivatives <strong>6</strong> were synthesized from monomethylhydrazine (phenylhydrazine) and ethyl acetoacetate.
Jian Wu, Linhong Jin, Qing Shi, Deyu Hu, Ming He, Zhuo Chen   +5 more
doaj   +1 more source

Targeting ParPMC Susceptibility Hubs in Prunus: eEF1A as a Conserved Mediator of Plum Pox Virus Infection in Nicotiana benthamiana

Molecular Plant Pathology, Volume 27, Issue 5, May 2026.
ParPMC interactors were screened, highlighting eEF1A proteins; co‐localization and VIGS show their role in PPV infection and sharka susceptibility. ABSTRACT Sharka, caused by Potyvirus plumpoxi (plum pox virus, PPV), is the most destructive viral disease affecting Prunus species worldwide.
Ángela Polo‐Oltra, Alba Lloret, Jesús A. Sánchez‐Navarro, Gabino Ríos, Carlos Romero, Elena Zuriaga   +5 more
wiley   +1 more source

Engineering the 3′‐UTR of Tobacco Vein Mottling Virus to Confer Cross‐Protection Against Potyviruses

Molecular Plant Pathology, Volume 27, Issue 5, May 2026.
The 3′‐untranslated region (3′‐UTR) and its secondary structure of virus genomic RNA of tobacco vein mottling virus (TVMV) are important in symptoms attenuation, which can be engineered for cross‐protection against further viral infection. We provide experimental evidence that supports the roles of 3′‐UTR in potyvirus infection.
Haijuan Wang, Zhenqi Sun, Baolong Zhang, Zhaoran Wu, Jiaxin Xu, Mingmin Zhao   +5 more
wiley   +1 more source

Cordyceps militaris Residue Extract Exhibits Potent Antiviral and Plant Growth-Promoting Effects

Agriculture
Cordyceps militaris is an important medicinal and edible fungus that contains a wide range of bioactive ingredients, including cordycepin, polysaccharides, ergosterol, mannitol, proteins, and carotenoids, which collectively confer tonic, anti-fatigue ...
Guoyue Song, Fangjin Zou, Fangping Sa, Weijia Li, Yifan Wang, Xiaoyan Zhang, Xianhao Cheng   +6 more
doaj   +1 more source

Resveratrol synthase homologs participate in infection of Nicotiana benthamiana by pathogenic plant viruses and fungi

Frontiers in Microbiology
IntroductionResveratrol synthase (RS) is a key enzyme involved in the synthesis of stilbene and resveratrol. Resveratrol has many biological pharmacological activities that are beneficial to human health including anti-cancer, cardiovascular protection ...
Zhuo Meng, Haijuan Wang, Guozhi Guo, Junxia Miao, Juan Liu, Hongyou Zhou, Hongyou Zhou, Mingmin Zhao, Mingmin Zhao, Baozhu Dong, Baozhu Dong   +10 more
doaj   +1 more source

Anti-TMV activity of flavonol derivatives containing piperidine sulfonamide: Design, synthesis, mechanism study

Arabian Journal of Chemistry
Zhiling Sun, Wei Zeng, Qing Zhou, Yujiao Qiu, Yuzhi Hu, Jieyu Li, Hong Fu, Hongqian Zou, Wei Xue   +8 more
openaire   +1 more source

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The anti-TMV potency of the tobacco-derived fungus Aspergillus versicolor and its active alkaloids, as anti-TMV activity inhibitors

Phytochemistry, 2023
Nicotiana tabacum (tobacco) has attracted interest as one of the most economically important industrial crops widely cultivated in China, whose dried leaves are popularly consumed medicinally and recreationally by human societies. In this study, five undescribed alkaloids derivatives, isoaspergillines A-E, together with eight known alkaloids, notoamide
Zhenjie Li, Qi-Li Mi, Jia-Meng Dai
exaly   +4 more sources