Results 161 to 170 of about 2,675,396 (301)

Concerted changes in the pediatric single-cell intestinal ecosystem before and after anti-TNF blockade. [PDF]

Elife
Zheng HB, Doran BA, Kimler K, Yu A, Tkachev V, Niederlova V, Cribbin K, Fleming R, Bratrude B, Betz K, Cagnin L, McGuckin C, Keskula P, Albanese A, Sacta M, de Sousa Casal J, van Esch R, Kwong AC, Kummerlowe C, Taliaferro F, Fiaschi N, Kou B, Coetzee S, Jalal S, Yabe Y, Dobosz M, Wipperman MF, Hamon SC, Kalliolias GD, Hooper A, Lim WK, Haxhinasto S, Wei Y, Ford M, Ambartsumyan L, Suskind DL, Lee D, Deutsch GH, Deng X, Collen LV, Mitsialis V, Snapper SB, Wahbeh G, Shalek AK, Ordovas-Montanes J, Kean LS.   +45 more
europepmc   +1 more source

Anti-TNF treatment in secondary amyloidosis [PDF]

Rheumatology, 2003
V, Ortiz-Santamaria, M, Valls-Roc, M, Sanmartí, A, Olive   +3 more
openaire   +2 more sources

AI Designed Conformation Locking Peptides Target STING to Restore Diabetic Wound Healing

Advanced Science, EarlyView.
A generative AI pipeline identifies SCP‐1, a conformation‐locking peptide that stabilizes inactive STING. Incorporated into a dual‐responsive hydrogel for localized, MMP‐9‐triggered release, SCP‐1 suppresses inflammation, promotes reparative macrophage polarization, and accelerates diabetic wound healing.
Xinyu Li, Haojie Fu, Zhe Wang, Xuanzhou Chen, Ruhong Zhang, Xudong Wang, Louis D. Zhang, Xiang Li, Datao Li   +8 more
wiley   +1 more source

Rocket‐Inspired Sequentially Targeted Nanotherapeutics for Mitochondrial Regulation and Inflammatory Reprogramming in Ischemic Stroke

Advanced Science, EarlyView.
A novel neutrophil‐hitchhiking, rocket‐inspired nanoplatform is developed to cross the blood‐brain barrier for sequential, spatiotemporal drug delivery. By responsive surface transformation in the ischemic penumbra, it precisely targets mitochondria to suppress Drp1‐mediated fission.
He Bai, Zihao Yong, Yang Li, Qingmin Chen, Yong Liu, Xiaomeng Guo, Fukai Li, Shicheng Tang, Zhuo Yang, Yufei Zhang, Ruwei Jie, Xiaohong Lv, Huacheng Wang, Chunming Huang, Liwei Xie, Jianqi Xiao, Qingchun Mu, Longguang Tang   +17 more
wiley   +1 more source

Anti-TNF-Alpha Associated Central Nervous System Demyelination. Drug-Induced Demyelination or Multiple Sclerosis Trigger? A Case Series. [PDF]

Clin Case Rep
Abutorabi-Zarchi M, Ziyaei A, Ghane D.
europepmc   +1 more source

Uninflamed colonic tissue harbors humoral activity linked to anti-TNF therapy non-response in ulcerative colitis. [PDF]

iScience
Walaas GAE, Sveaas S, Kuraas LF, Sridhar A, Lillebråten K, Fossen H, Pettersen HS, Flatberg A, Granlund AVB, Sandvik AK, Østvik AE, Bruland T, Bakke I.   +12 more
europepmc   +1 more source

Reorganization of Innate Immune Cell Lipid Profiles by Bioinspired Meroterpenoids to Limit Inflammation

Advanced Science, EarlyView.
Resolution pharmacology is an emerging strategy to tackle inflammatory pathologies. Bioinspired meroterpenoids induce a lipid mediator class switch toward inflammation resolution in vitro and in vivo by targeting key nodes in lipid mediator biosynthesis and neutral lipid dynamics.
Lorenz Waltl, David Holubek, Klaus Speck, Raphael Wildermuth, Franz‐Lucas Haut, Stephan Permann, Immanuel Plangger, Christian Steinborn, Zhigang Rao, Danilo D'Avino, Ida Cerqua, Julia Stadler, Fiorentina Roviezzo, Peter Schlenke, Anita Siller, Harald Schennach, Solveigh C. Koeberle, Eva‐Maria Pferschy‐Wenzig, Antonietta Rossi, Thomas Magauer, Andreas Koeberle   +20 more
wiley   +1 more source

Anti-TNF therapy attenuates the diagnostic utility of leucine-rich α2-Glycoprotein 1 for endoscopic activity in ulcerative colitis. [PDF]

Ther Adv Gastroenterol
Dejima A, Takatori H, Miyazawa M, Okafuji H, Hayashi T, Seki A, Nio K, Iida N, Yamada S, Shimakami T, Toyama T, Yamashita T.   +11 more
europepmc   +1 more source

Innovative Test Strip‐Based Colorimetric Sensors Integrated With Affinity Chromatography: Acetylcholinesterase Inhibitor Screening Breakthrough in Lycium Barbarum Leaves

Advanced Science, EarlyView.
Schematic diagrams illustrating the breakthrough in the screening of AChE inhibitors from LBL, and the research process of the pharmacodynamics of the NCP are presented. ABSTRACT Current Alzheimer's drugs exhibit limited effectiveness, highlighting the necessity for multi‐target treatments.
Yuping Sa, Hui Yuan, Jingui Ma, Zhigang Yang, Mei Wang, Weibiao Wang, Lingling Yang, Fen Ma, Weiman Zhang, Gidion Wilson Mening'oo, Guoning Chen, Xueqin Ma   +11 more
wiley   +1 more source

Multiple Modes of Action of Anti-TNF-α Antibodies for Inflammatory Bowel Diseases Beyond TNF-α Neutralization. [PDF]

Antibodies (Basel)
Watanabe T, Kudo M.
europepmc   +1 more source