Results 91 to 100 of about 8,525,247 (262)

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Christian Anti-Communism Crusade - Invitation to a lecture on current communist conflicts

open access: yes, 1966
Christian Anti-Communism Crusade - Invitation to a lecture on current communist ...
Christian Anti-Communism Crusade
core  

Anti-TT and anti-DT IgG titres in cohort 2 patients with CKD and controls with known vaccination history.

open access: yes, 2018
Antigen-specific IgG titres (μg/ml) in cohort 2 CKD patients and age-matched controls (n = 22 and 19 respectively) are shown with medians for individuals vaccinated with TT/DT booster in preceding 10 years (blue) and those who were not (orange).
Marisol Perez-Toledo (5105255)   +14 more
core   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Christian Anti-Communism Crusade - Invitation to a lecture by Dr. F.C. Schwarz

open access: yes, 1963
Christian Anti-Communism Crusade - Invitation to a lecture by Dr.
Christian Anti-Communism Crusade
core  

Changing, priming, and acting on values: Effects via motivational relations in a circular model

open access: yes, 2009
Circular models of values and goals suggest that some motivational aims are consistent with each other, some oppose each other, and others are orthogonal to each other.
Maio, Gregory R.   +5 more
core   +1 more source

Corruption, Politics and Societal values in Tanzania: An evaluation of the Mkapa administration's anti corruption efforts

open access: yesAfrican Journal of Political Science, 2004
Array
Bruce Heilman, Lawrean Ndumbaro
doaj  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Christian Anti-Communism Crusade - Circular letters, Brisbane, October, 1962 to November, 1966

open access: yes, 1962
Christian Anti-Communism Crusade - Circular letters, Brisbane, October, 1962 to November ...
Christian Anti-Communism Crusade
core  

Anti-oxidative capability.

open access: yes, 2016
The anti-oxidative activity of HDL was determined by inhibition of AAPH-initiated oxidation of the fluorescent dye dihydrorhodamine (DHR). Incubation of DHR in presence of apoB-depleted sera from healthy subjects or AMD patients led to a reduction in the
Anton Haas (420487)   +9 more
core   +1 more source

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