Results 111 to 120 of about 8,525,247 (262)

Nutritional and anti-nutritional properties and oil potential of Balanites rotundifolia (Tiegh.) Blatt seeds: Evidence from laboratory analysis in South Omo Zone, Southern Ethiopia

Applied Food Research
Many wild and semi-wild plants are consumed in remote parts of Ethiopia, among which Balanites rotundifolia (Tiegh.) Blatt is an important semi-wild edible plant used by some ethnic communities in the southern region.
Tanje Mada, Abambagade Abera, Demisie Dakone, Sayge Sate   +3 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

What works for whom in school-based anti-bullying interventions? An individual participant data meta-analysis

, 2023
: The prevalence of bullying worldwide is high (UNESCO, 2018). Over the past decades, many anti-bullying interventions have been developed to remediate this problem.
Kuijper, Steven C., Hensums, Maud, BIRC: the anti-Bullying Interventions Research Consortium, Overbeek, Geertjan, de Mooij, Brechtje, Fekkes, Minne, DeSmet, Ann   +6 more
core  

Nilai-Nilai Anti Korupsi dalam Pemikiran KH. Sahal Mahfudh dan Diseminasinya pada Perguruan Tinggi Pesantren

Islamic Review
The thoughts of KH. MA. Sahal Mahfudh in his fiqh sosial reflects anti-corruption values that are relevant to the main function of humans as Khalifatullah. This function implies two main tasks, namely Ibadatullah and Imaratul Ardh.
Latifah Nuraini, Irma Nur Af'idah, Fira Nadliratul Afrida, Maulana Irfan Nasa'i   +3 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Annual report.

The reports for 1857 and 1858 are published in one volume, with a common title-page and continuous pagination. The report for 1860 has cover-title "The anti-slavery history of the John-Brown year; being the twenty-seventh annual report of the American ...
American Anti-Slavery Society.
core  

Values in Psychotherapy

, 1996
There is a tension between those who hold that psychotherapy is a scientific discipline and therefore "value-free," and those who believe that values are inherent in the nature of psychotherapy.
Holmes, Jeremy
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Determination of reference change values for thyroid-related biomarkers: TSH, fT3, fT4, Tg, Anti-Tg, and Anti-TPO

Türk Biyokimya Dergisi
Reference change value (RCV) is an objective tool that indicates whether the change between consecutive measurements is clinically significant. This study aimed to determine the instrument-specific RCVs of thyroid-stimulating hormone (TSH), free ...
Bildirici Mehmet Akif, Aliyazıcıoğlu Yüksel, Yaman Hüseyin, Karahan Süleyman Caner, Örem Asım   +4 more
doaj   +1 more source