Results 121 to 130 of about 7,382,706 (304)

What works for whom in school-based anti-bullying interventions? An individual participant data meta-analysis

, 2023
: The prevalence of bullying worldwide is high (UNESCO, 2018). Over the past decades, many anti-bullying interventions have been developed to remediate this problem.
Kuijper, Steven C., Hensums, Maud, BIRC: the anti-Bullying Interventions Research Consortium, Overbeek, Geertjan, de Mooij, Brechtje, Fekkes, Minne, DeSmet, Ann   +6 more
core  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Nilai-Nilai Anti Korupsi dalam Pemikiran KH. Sahal Mahfudh dan Diseminasinya pada Perguruan Tinggi Pesantren

Islamic Review
The thoughts of KH. MA. Sahal Mahfudh in his fiqh sosial reflects anti-corruption values that are relevant to the main function of humans as Khalifatullah. This function implies two main tasks, namely Ibadatullah and Imaratul Ardh.
Latifah Nuraini, Irma Nur Af'idah, Fira Nadliratul Afrida, Maulana Irfan Nasa'i   +3 more
doaj   +1 more source

Evaluation of the possible association between acantholysis and anti‐desmogleins 1 and 3 values in pemphigus vulgaris and pemphigus foliaceus

Journal of Cutaneous Immunology and Allergy, 2019
Objectives Acantholysis is the main pathologic finding in pemphigus, and its location has been historically used to distinguish the major subtypes of pemphigus vulgaris (PV) and pemphigus foliaceus (PF).
Maryam Mobarakabadi, Nazanin Rajai, Kambiz Kamyab, Kamran Balighi, Hamidreza Mahmoudi, Soheil Tavakolpour, Ali Nili, Azita Nikoo, Farnam Mohebi, Maryam Daneshpazhooh   +9 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Pamphlet: Coalition for Democratic Values [PDF]

, 2019
Membership form and information pamphlet for The Coalition for Democratic Values. No date given.
The Coalition for Democratic Values
core   +1 more source

Nutritional and anti-nutritional properties and oil potential of Balanites rotundifolia (Tiegh.) Blatt seeds: Evidence from laboratory analysis in South Omo Zone, Southern Ethiopia

Applied Food Research
Many wild and semi-wild plants are consumed in remote parts of Ethiopia, among which Balanites rotundifolia (Tiegh.) Blatt is an important semi-wild edible plant used by some ethnic communities in the southern region.
Tanje Mada, Abambagade Abera, Demisie Dakone, Sayge Sate   +3 more
doaj   +1 more source

Decoupled Coverage Anti-Aliasing

, 2015
State-of-the-art methods for geometric anti-aliasing in real-time rendering are based on Multi-Sample Anti-Aliasing (MSAA), which samples visibility more than shading to reduce the number of expensive shading calculations.
Sen, Pradeep, Wyman, Chris, Wang, Yuxiang, He, Yong   +3 more
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source