Molecular docking based design of Inhibitors for viral Non-Nucleosidase as potential anti-retroviral agents. [PDF]
Bioinformation, 2020 Reverse Transcriptase (RT) inhibitors are highly promising agents for use as an effective anti-retroviral therapy (HAART) which is typically a combination of three or four antiretroviral drugs. We used direct drug design approach to discover new chemical entities for the target protein.
Alharbi A, Alshaghdali K, Saeed A.
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Is Routine Therapeutic Drug Monitoring of Anti-Retroviral Agents Warranted in Children Living with HIV? [PDF]
J Pediatr Pharmacol Ther, 2022 OBJECTIVE The utility of routine therapeutic drug monitoring (TDM) in children living with HIV has not been extensively studied. The purpose of this study was to assess this strategy. METHODS This was a single-center, prospective observational study of routine TDM for protease inhibitors (PIs),
Tam J, Lau E, Read S, Bitnun A.
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Retrovirusses and Anti-retroviral agents
South African Family Practice, 2001 This edition was originally meant to focus mainly on an understanding of antiretroviral agents. However, I have taken a rather round about route and in the'back to basics' section have concentrated on retroviruses themselves, including HIV- | and HIV-2 ...
Roy Jobson
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Case Report: Remission of a patient with complex combination of autoimmune diseases by anti-CD19 CAR-T cell therapy [PDF]
Frontiers in ImmunologyCAR−T cell therapy has been proven effective in various autoimmune diseases, with most studies utilizing lentiviral‐transduced CAR−T cells. In recent years, retroviral vector−transduced CAR−T cells—characterized by a high positivity rate, stable cell ...
Xudong Liu +12 more
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Mechanisms mediating the effects of alcohol and HIV anti-retroviral agents on mTORC1, mTORC2 and protein synthesis in myocytes. [PDF]
World J Biol Chem, 2012 Alcoholism and acquired immune deficiency syndrome are associated with severe muscle wasting. This impairment in nitrogen balance arises from increased protein degradation and a decreased rate of protein synthesis. The regulation of protein synthesis is a complex process involving alterations in the phosphorylation state and protein-protein interaction
Hong-Brown LQ, Kazi AA, Lang CH.
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Dolutegravir combined anti-retroviral agents as second-line drugs and virologic suppression of adults with HIV in Federal Teaching Hospital, Ido Ekiti - case series. [PDF]
Pan Afr Med JThe transition to dolutegravir (DTG)-combined anti-retroviral therapy (ART) as a preferred option in both first- and second-line for all populations was adopted by the World Health Organization (WHO) due to encouraging safety data for women and adolescent girls during the peri-conception period.
Ajetunmobi OA +6 more
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Safety of antiretrovirals in pregnacy [PDF]
Vojnosanitetski Pregled, 2011 nema
Dragović Gordana +5 more
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Tenofovir-induced renal and bone toxicity: report of two cases and literature review [PDF]
Revista do Instituto de Medicina Tropical de São Paulo, 2022 Tenofovir Disoproxil Fumarate (TDF) is one of the drugs in the initial first-line antiretroviral regimen for the treatment of hepatitis B and HIV infections. Despite its effectiveness and few adverse effects, it is related to renal and bone toxicity.
Carlos Eduardo Andrade Fioroti +6 more
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Brazilian Journal of Pharmaceutical Sciences, 2022 Highly Active Antiretroviral therapy (HAART) depends on optimal adherence to be effective. Pharmacotherapeutic follow-up can be used as a strategy for treatment fidelity. To provide pharmaceutical care for HAART patients, to assess adherence, to identify
Marcio Rodrigo Schoenherr +3 more
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Adherence to HIV post-exposure prophylaxis in a specialized service in São Paulo, Brazil
Journal of Infection in Developing Countries, 2023 Introduction: The effectiveness of human immunodeficiency virus (HIV) post-exposure prophylaxis (PEP) depends on adherence to the protocol, which includes taking antiretrovirals (ARVs) and attending visits.
Marcos Morais Santos Silva +2 more
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