Results 41 to 50 of about 39,168 (176)

Mimic, target, and adapt: Cell membrane‐coated nanoplatforms for precision and immune‐guided cancer treatment

BMEMat, EarlyView.
This Perspective explores the emerging landscape of cell membrane‐coated nanoparticles (CM‐NPs) as intelligent, immune‐compatible platforms for cancer therapy. Highlighting design strategies, translational challenges, and competitive positioning, it outlines how integrating biomimetic targeting with advanced analytical and manufacturing tools could ...
A. K. M. M. Alam, Xiaojun Cai, Malik Ihsan Ullah Khan, Robert Musiol, Quazi T. H. Shubhra   +4 more
wiley   +1 more source

Factors associated with dyslipidemia in seropositive patients for human immunodeficiency virus. Fadevic study.

Revista Ciencias Biomédicas, 2012
Introduction: with the argument of life expectancy of the people affected by HIV/AIDS, new challenges of health emerged. The dyslipidemias, in special, are presentedas a complication of the infection by the virus and the antiretroviral treatment(ARV). In
Velaides-Morelo Alberto, De la Vega-Del Risco Fernando, Bello-Espinosa Ariel   +2 more
doaj  

Hemophilia A: An Ideal Disease for Prenatal Therapy

Prenatal Diagnosis, EarlyView.
ABSTRACT Hemophilia A (HA) is the most common inherited coagulation defect. Current state‐of‐the‐art treatment consists of frequent administration of prophylactic infusions of coagulation factor VIII (FVIII) protein or bispecific antibodies that replace the cofactor function of FVIIIa to maintain hemostasis. However, these treatments are far from ideal,
Christopher D. Porada, Anthony Atala, Graça Almeida‐Porada   +2 more
wiley   +1 more source

Evaluation of the Impact of Anti-Retroviral Therapy on the Prevalence of Oral Lesions in Human Immunodeficiency Virus Infected Patients

پزشکی بالینی ابن سینا, 2013
Introduction & Objective: Oral lesions have important diagnostic and prognostic roles in HIV infected patients. It seems that HAART reduces the prevalence of oral lesions. The aim of the present study was to evaluate the prevalence of oral lesions in HIV
Poorandokht Davoodi, Hamidreza Abdolsamadi, Shabnam Seyedzadeh Saboonchi, Mina Jazaeri   +3 more
doaj  

[Study of interactions between anti-retroviral agents and concomitant drugs].

Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria, 2003
Clinical efficacy of antiretroviral treatment requires drugs to maintain a plasma concentration over MIC90. One of the facts that can prevent drugs from reaching and maintaining required concentrations are pharmacological drug interactions.The aim of this study is to identify the main interactions between antiretroviral medicines and concomitant ...
M A, Mur Lalaguna, R, Cobo Campos, M F T, Hurtado Gómez, M J, Martínez Tutor   +3 more
openaire   +1 more source

Disruption of iron metabolism resulting from Dmt1/Slc11a2 deficiency compromises Notch protein degradation and transcriptional activation

The FEBS Journal, EarlyView.
Divalent metal transporter 1 (Dmt1) maintains iron homeostasis and lysosomal proteostasis required for physiological Notch receptor–ligand signaling. Dmt1 loss lowers iron storage capacity (ferritin), increasing intracellular Fe2+, driving ROS and lipid peroxidation, and leading to lysosomal/mitochondrial dysfunction.
Rui Zhang, Somaieh Ahmadian, Jolanda Piepers, Florian Bock, Tom Keulers, Marc A. Vooijs   +5 more
wiley   +1 more source

Risk of severe bacterial infections including TB before and after immediate or deferred antiretroviral therapy: A multicenter, prospective, cohort study

International Journal of Infectious Diseases
Objectives: Deferring antiretroviral therapy (ART) until a CD4 count below cells/mm3 or other clinical indication in people with HIV (PWH) carries an increased risk of severe bacterial infections and tuberculosis (TB).
Tomas O. Jensen, Shweta Sharma, Anchalee Avihingsanon, Joseph Lutaakome, Indira Brar, William Burman, Ploenchan Chetchotisakd, Nathalie de Castro, Juan-Francisco Galán-Herrera, Nagalingeswaran Kumarasamy, Roger Paredes, Rene Ridzon, Michael Sciaudone, Kanal Singh, Alison Uriel, Jens Lundgren, Cavan Reilly, Gail Matthews   +17 more
doaj   +1 more source

A Tale of Two Conditions: 50 Years of Chronic Illness and Cancer From a Nursing Perspective

Journal of Advanced Nursing, EarlyView.
ABSTRACT Introduction In this commentary, I consider the disparity between the care we see as a necessity for cancer patients and the lack of care we afford to many persons with chronic disease. Background I ground my arguments in my own clinical practice and research experiences over a 50‐year period augmented by reference to available literature ...
Sally Thorne
wiley   +1 more source

Antiretroviral drug use by individuals living with HIV/AIDS and compliance with the Clinical Protocol and Therapy Guidelines

Einstein (São Paulo), 2020
Objective To describe antiretroviral treatment regimens prescribed and their compliance with the Clinical Protocol and Therapy Guidelines of the Ministry of Health for the management of HIV infection.
Lucas Eduardo Fedaracz Brojan, Leticia Mara Marca, Frederico Alves Dias, Yanna Dantas Rattmann   +3 more
doaj   +2 more sources

Indirect comparison of 48-week efficacy and safety of long-acting cabotegravir and rilpivirine maintenance every 8 weeks with daily oral standard of care antiretroviral therapy in participants with virologically suppressed HIV-1-infection

BMC Infectious Diseases, 2022
Background Efficacy and safety of long-acting cabotegravir (CAB) + rilpivirine (RPV) every 8 weeks (Q8W) versus daily oral standard of care (SoC) maintenance in treatment-experienced individuals with virologically suppressed human immunodeficiency virus ...
Vasiliki Chounta, Sonya J. Snedecor, Sterling Wu, Nicolas Van de Velde   +3 more
doaj   +1 more source