Results 31 to 40 of about 42,053 (270)

Effects of Antiarrhythmic Drugs on the Hyperpolarization-Activated Cyclic Nucleotide–Gated Channel Current

Journal of Pharmacological Sciences, 2009
.: After the report of the Cardiac Arrhythmia Suppression Trial, a tabular framework of the Sicilian Gambit has been proposed to display actions of antiarrhythmic drugs on ion channels and receptors and to provide more rational pharmacotherapy of ...
Atsushi Tamura, Takehiko Ogura, Hiroko Uemura, Yoshie Reien, Takashi Kishimoto, Toshio Nagai, Issei Komuro, Masaru Miyazaki, Haruaki Nakaya   +8 more
doaj   +1 more source

Attenuation and Structural Transformation of Crassicauline A During Sand Frying Process and Antiarrhythmic Effects of its Transformed Products

Frontiers in Pharmacology, 2021
To ensure safety and efficacy, most Aconitum herbs should be processed before clinical application. The processing methods include boiling, steaming, and sand frying.
Pei Tao, Yan Wang, Yujie Wang
doaj   +1 more source

Rate-Control or Rhythm-Contol: Where do we stand? [PDF]

, 2005
Atrial fibrillation is the most common sustained rhythm disturbance and its prevalence is increasing worldwide due to the progressive aging of the population.
A, Dello Russo, F, Andreotti, F, Bellocci, G, Pelargonio, G, Trotta, L, Testa, M, Casella   +6 more
core   +1 more source

Acute echocardiographic effects of sotalol on ventricular systolic function in dogs with ventricular arrhythmias. [PDF]

, 2018
BackgroundSotalol is a commonly used antiarrhythmic drug that may alter ventricular function.ObjectiveTo determine the effect of sotalol on echocardiographic indices of ventricular systolic function in dogs with ventricular arrhythmias.AnimalsThirty-five
Anderson, Baumwart, Chetboul, Cornell, Dukes-McEwan, Hansson, Hoffmann, Hohnloser, Kaye, Mahmarian, Maran, Martin, Meurs, Meurs, Meurs, Meurs, Motskula, Oyama, Palermo, Peralta, Schnelle, Seidler, Singh, Smets, Stephenson, Summerfield, Visser, Visser, Wess, Wess, Zupan   +30 more
core   +2 more sources

TWEAK/Fn14 signaling drives oxidative cardiac injury in systemic lupus erythematosus: Evidence from patient biomarker studies, lupus mouse models, and cardiomyocyte assays

Arthritis &Rheumatology, Accepted Article.
Objective Cardiac involvement is a major cause of morbidity in systemic lupus erythematosus (SLE). Tumor necrosis factor–like weak inducer of apoptosis (TWEAK) is elevated in SLE, but its contribution to lupus‐associated cardiac injury is unclear. We investigated the role of TWEAK/Fn14 signaling in SLE‐related cardiomyopathy and its potential as a ...
Yale Liu, Zhu Yan, Xueting Peng, Meixuan Li, Juan Wang, Yan Zhang, Xiaoqian Hu, Mingzhu Zhou, Kaixuan Ren, Dan Zhang, Xingyi Guo, Yumin Xia, Huanhuan Huo   +12 more
wiley   +1 more source

An algorithm for the selection of antiarrhythmic drugs for clinical pharmacologist

Медицинский совет, 2014
The choice of antiarrhythmic drugs (AAD) should be based on a certain algorithm comprising at its first stage selection of effective drugs (if applicable), at the second stage - exclusion from the list of the selected drugs those which may be dangerous ...
A. A. Upnitskiy
doaj   +1 more source

Differential effects of class I antiarrhythmic drugs on the guinea pig pulmonary vein myocardium: Inhibition of automatic activity correlates with blockade of a diastolic sodium current component

Journal of Pharmacological Sciences, 2020
The effects of class I antiarrhythmic drugs on the automaticity of isolated guinea pig pulmonary vein myocardia were investigated using microelectrode and voltage clamp methods.
Masahiko Irie, Haruhito Hiiro, Shu Kato, Mizuki Kuramochi, Shogo Hamaguchi, Iyuki Namekata, Hikaru Tanaka   +6 more
doaj   +1 more source

Frequency Analysis of Atrial Fibrillation From the Surface Electrocardiogram [PDF]

, 2004
Atrial fibrillation (AF) is the most common arrhythmia encountered in clinical practice. Neither the natural history of AF nor its response to therapy are sufficiently predictable by clinical and echocardiographic parameters.
Bollmann, Andreas, Husser, Daniela, Olsson, Bertil, Sornmo, Leif, Stridh, Martin   +4 more
core  

Comparative effectiveness and safety of oral anticoagulants in patients with atrial fibrillation using antiarrhythmic drugs: An international cohort study

British Journal of Clinical Pharmacology, EarlyView.
Aim Our international cohort study assessed the comparative effectiveness and safety of direct oral anticoagulants (DOACs) and vitamin K antagonists (VKAs) among patients with non‐valvular atrial fibrillation (NVAF) using antiarrhythmic drugs. Methods Using the United Kingdom's (UK's) Clinical Practice Research Datalink Aurum and Québec claims data, we
Fabian Maximilian Meinert, Jenny Dimakos, Ying Cui, Kristian B. Filion, Christel Renoux, Antonios Douros   +5 more
wiley   +1 more source

Therapy for patient with atrial fibrillation: in search of a balance between efficacy and safety

Клинический разбор в общей медицине
This paper analyzes aspects of the efficacy and safety of antiarrhythmic drugs in the treatment of atrial fibrillation. It considers drug-drug interactions of antiarrhythmics with other drugs, especially in the near circle, i.e.
Yakov G. Bozhko, Inna I. Reznik, Mikhail V. Arkhipov   +2 more
doaj   +1 more source