Results 81 to 90 of about 52,848 (330)

Efficacy of omega‐3 fatty acids as a functional food: a multifaceted approach to health reinforcement

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Omega‐3 fatty acids (omega‐3s) are polyunsaturated fatty acids linked with numerous health benefits. Omega‐3s exhibit multifaceted activities through various mechanisms. Eicosapentaenoic acid (EPA) alleviates oxidative stress by lowering reactive oxygen species and improving oxidative stress in brain tissues and acts against neurodegenerative ...
Md Faruque Ahmad, Abdulrahman A Alsayegh, Anjum Khanam, Awais Ahmed, António Raposo, Farkad Bantun, Md Zeyaullah, Ahmad O Babalghith, Abdullah F Aldairi, Boshra Mozaffar, Mohammed F Bajahzer, Mohamed H Abdelrahman, Mohammad Intakhab Alam   +12 more
wiley   +1 more source

A Cross-Sectional Study Comparing the Frequency of Drug Interactions After Adding Simeprevir- or Sofosbuvir-Containing Therapy to Medication Profiles of Hepatitis C Monoinfected Patients. [PDF]

, 2015
INTRODUCTION:This study compares the expected occurrence of contraindicated drug-drug interactions (XDDIs) when simeprevir (SIM)- or sofosbuvir (SOF)-containing therapy is added to medication profiles of patients with hepatitis C (HCV) monoinfection to ...
Bliss, Steven, Davis, Melissa, Koroglu, Arden, McNutt, Louise-Anne, Miller, Christopher, Nasiri, Mona, Patel, Nimish   +6 more
core   +1 more source

Autophagy Plays a Suppressive Role in Bladder Tumor Formation in an Orthotopic Mouse Model and Bladder Cancer Patient Specimens

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Autophagy plays either a suppressing or promoting role during tumor development. Clarifying the role of autophagy in bladder tumorigenesis both in vitro and in vivo is crucial for developing novel therapeutic strategies through manipulating autophagy activity.
Wan‐Ting Kuo, Chin‐Chen Pan, Yi‐Wen Liu, Nan‐Haw Chow, Hong‐Lin Cheng, Shan‐Ying Wu, Sheng‐Hui Lan, Chih‐Peng Chang, Hsiao‐Sheng Liu   +8 more
wiley   +1 more source

Cost-effectiveness of left ventricular assist devices (LVADs) for patients with advanced heart failure : analysis of the British NHS Bridge to Transplant (BTT) program [PDF]

, 2001
Background: A previous cost-effectiveness analysis showed that bridge to transplant (BTT) with early design left ventricular assist devices (LVADs) for advanced heart failure was more expensive than medical management while appearing less beneficial ...
Aileen Clarke, Ruth Pulikottil-Jacob, Martin Connock, Gaurav Suri, Ngianga-Bakwin Kandala, Hendramoorthy Maheswaran, Nicholas R. Banner, Paul Sutcliffe, Aaronson, Garber, Weinstein, Slaughter, Temple, MacGowan, Clegg, Clegg, Sharples, Sharples, Sharples, Slaughter, Sharples, National Institute for Health and Clinical Excellence, Gohler, Rogers, Personal social services research unit, Briggs, Levy, Schaffer, Strueber, Rose, Stevenson, National Institute for Health and Clinical Excellence, Moreno, Pagani   +33 more
core   +9 more sources

Unambiguous Assignment of the 1H- and 13C-NMR Spectra of Propafenone and a Thiophene Analogue

Molecules, 2001
Full and unambiguous asssignment of all 1H- and 13C-NMR resonances of the free bases as well as the hydrochloride salts of the antiarrhythmic agent propafenone and a thiophene analogue in different solutions (DMSO-d6, CDCl3) is reported.
Wolfgang Holzer
doaj   +1 more source

Managing atrial fibrillation in the global community: The European perspective. [PDF]

, 2013
Atrial fibrillation is a common, global problem, with great personal, economic and social burdens. As populations age it increases in prevalence and becomes another condition that requires careful chronic management to ensure its effects are minimised ...
Camm, AJ, Kaba, RA, Sharma, R, Williams, TM   +3 more
core   +1 more source

A Novel Method Using Dual‐Energy Computed Tomography for Detecting Amiodarone‐Induced Lung Injury: A Cohort Pilot Study

Respirology, EarlyView.
There is no gold standard for detecting amiodarone‐induced‐lung injury (AILD). Dual‐Energy‐Computed‐Tomography (DECT) depicts iodine deposition in lungs abnormalities and the liver. We found a substantial correlation between the DECT assessment of AILD and comprehensive clinical evaluation of AILD. DECT can assist in the diagnosis of AILD.
Naama R. Bogot, Ariel Rokach, Irith Hadas‐Halperen, Yehonatan Cohen, Ayal Romem, Moshe Rav‐Acha, Tal Hasin, Gabriel Izbicki, Nissim Arish   +8 more
wiley   +1 more source

Theoretical basis and search for new methods of cardiac arrhythmias' pathogenetic therapy

Российский кардиологический журнал, 2005
Efficacy of cardiac arrhythmias (CA) pharmacotherapy does not exceed 70%; incidence of adverse effects, causing treatment discontinuation, is as high as 10-30%. The need for CA pharmacotherapy improvement is obvious.
V. M. Moroz, T. N. Lipnitsky
doaj  

Comparing the Impact of Different Antiarrhythmic Classes on Clinical Outcomes Following Atrial Fibrillation Catheter Ablation

Pharmaceuticals
Background/Objectives: Catheter ablation has become the standard of care for patients with symptomatic and drug-refractory atrial fibrillation (AF). Both Class IC and Class III antiarrhythmic drugs (AADs) are effective in preventing early recurrences of ...
Andrej Belančić, Yusuf Ziya Sener, Metin Oksul, Cansu Ozturk, Serdar Soner, Adnan Duha Comert, Gamze Yeter Arslan, Dinko Vitezić, Bojan Jelaković, Erkan Baysal   +9 more
doaj   +1 more source

Functional selectivity of GPCR-directed drug action through location bias. [PDF]

, 2017
G-protein-coupled receptors (GPCRs) are increasingly recognized to operate from intracellular membranes as well as the plasma membrane. The β 2 -adrenergic GPCR can activate G s -linked cyclic AMP (G s -cAMP) signaling from endosomes.
Conti, Marco, Huang, Bo, Irannejad, Roshanak, Mika, Delphine, Pessino, Veronica, von Zastrow, Mark, Wedegaertner, Philip B.   +6 more
core   +3 more sources