Results 1 to 10 of about 448,880 (299)

Syncollin is an antibacterial polypeptide [PDF]

open access: yesCellular Microbiology, 2021
Funder: AstraZeneca; Id: http://dx.doi.org/10.13039 ...
Waters, Rosie A   +2 more
openaire   +3 more sources

Comparative Transcriptome-Based Mining of Genes Involved in the Export of Polyether Antibiotics for Titer Improvement

open access: yesAntibiotics, 2022
The anti-coccidiosis agent salinomycin is a polyether antibiotic produced by Streptomyces albus BK3-25 with a remarkable titer of 18 g/L at flask scale, suggesting a highly efficient export system.
Xian Liu   +5 more
doaj   +1 more source

Identification of an antivirulence agent targeting the master regulator of virulence genes in Staphylococcus aureus

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
The emergence of bactericidal antibiotic-resistant strains has increased the demand for alternative therapeutic agents, such as antivirulence agents targeting the virulence regulators of pathogens. Staphylococcus aureus exoprotein expression (sae) locus,
Rekha Arya   +5 more
doaj   +1 more source

New Antibacterials? [PDF]

open access: yesCanadian Journal of Infectious Diseases and Medical Microbiology, 2010
Peer ...
Laupland, Kevin B., Fisman, David N.
openaire   +4 more sources

Biosynthesis of ansamitocin P-3 incurs stress on the producing strain Actinosynnema pretiosum at multiple targets

open access: yesCommunications Biology, 2023
Microbial bioactive natural products mediate ecologically beneficial functions to the producing strains, and have been widely used in clinic and agriculture with clearly defined targets and underlying mechanisms.
Qungang Huang   +6 more
doaj   +1 more source

Antibacterial Silver [PDF]

open access: yesMetal-Based Drugs, 1994
The antibacterial activity of silver has long been known and has found a variety of applications because its toxicity to human cells is considerably lower than to bacteria. The most widely documented uses are prophylactic treatment of burns and water disinfection. However, the mechanisms by which silver kills cells are not known.
Clement, Julia L., Jarrett, Penelope S.
openaire   +2 more sources

Unconventional Antibacterials and Adjuvants

open access: yesAccounts of Chemical Research, 2021
The need for new classes of antibacterials is genuine in light of the dearth of clinical options for the treatment of bacterial infections. The prodigious discoveries of antibiotics during the 1940s to 1970s, a period wistfully referred to as the Golden Age of Antibiotics, have not kept up in the face of emergence of resistant bacteria in the past few ...
Mayland Chang   +3 more
openaire   +5 more sources

Antibacterial Hydrogels [PDF]

open access: yesAdvanced Science, 2018
AbstractAntibacterial materials are recognized as important biomaterials due to their effective inhibition of bacterial infections. Hydrogels are 3D polymer networks crosslinked by either physical interactions or covalent bonds. Currently, hydrogels with an antibacterial function are a main focus in biomedical research.
Shuqiang Li   +7 more
openaire   +2 more sources

The oxadiazole antibacterials [PDF]

open access: yesCurrent Opinion in Microbiology, 2016
The oxadiazoles are a class of antibacterials discovered by in silico docking and scoring of compounds against the X-ray structure of a penicillin-binding protein. These antibacterials exhibit activity against Gram-positive bacteria, including against methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus (VRE).
Shahriar Mobashery   +2 more
openaire   +3 more sources

Antibacterial Peptides [PDF]

open access: yesAntibiotics, 2020
As natural host defense compounds produced by numerous prokaryotic and eukaryotic life forms, antimicrobial peptides (AMPs) are now emerging as solid candidate chemotherapeutic drugs to fight against the various types of pathogenic Gram-positive and Gram-negative bacteria, especially those resistant to current antibiotics [...]
openaire   +4 more sources

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