Results 21 to 30 of about 237,028 (256)

Application of Polymeric Nanocarriers for Enhancing the Bioavailability of Antibiotics at the Target Site and Overcoming Antimicrobial Resistance

Applied Sciences, 2021
Antimicrobial resistance is one of the greatest threats to global health. Although the efforts in antibiotic drug discovery continue to play a pivotal role, this solution alone probably will not be enough to ensure the required level of infection control
Hung Le, Carole Karakasyan, Thierry Jouenne, Didier Le Cerf, Emmanuelle Dé   +4 more
doaj   +1 more source

Drug-target binding quantitatively predicts optimal antibiotic dose levels in quinolones.

PLoS Computational Biology, 2020
Antibiotic resistance is rising and we urgently need to gain a better quantitative understanding of how antibiotics act, which in turn would also speed up the development of new antibiotics.
Fabrizio Clarelli, Adam Palmer, Bhupender Singh, Merete Storflor, Silje Lauksund, Ted Cohen, Sören Abel, Pia Abel Zur Wiesch   +7 more
doaj   +1 more source

Evidence of the Efficacy of Flurbiprofen 8.75 mg Lozenges for Patients Receiving Antibiotics for Laboratory-Confirmed Streptococcal Pharyngitis

Ear, Nose & Throat Journal, 2023
Objectives: To determine the efficacy of flurbiprofen 8.75 mg lozenges for patients with laboratory-confirmed streptococcal pharyngitis both before and concomitant with antibiotics.
Bernard Schachtel MD, Adrian Shephard BSc, Emily Schachtel BA, Tim Shea BS, Adam Smith PhD, Evi Tselenti MRes   +5 more
doaj   +1 more source

PHARMACOECONOMIC ANALYSIS OF EFFICACY OF DIFFERENT MODES OF ANTIBIOTIC PROPHYLAXIS IN CHOLECYSTECTOMY

Вестник хирургии имени И.И. Грекова, 2016
Pharmacoeconomic assessment of efficacy of different modes of antibiotic prophylaxis was made in 27 patients with diagnosis of acute calculous cholecystitis using method of «cost-efficacy».
A. N. Poborskiy, N. I. Ponamarev, Sh. D. Asutaev   +2 more
doaj   +1 more source

Reliability and validity evaluation of the appropriate antibiotic use self-efficacy scale for Chinese adults

BMC Public Health, 2022
Background Antibiotic resistance is one of the greatest threats to global public health. Inappropriate use of antibiotics can lead to an increase in antibiotic resistance.
Liying Wang, Chunguang Liang, Haitao Yu, Hui Zhang, Xiangru Yan   +4 more
doaj   +1 more source

Efficacy of antibiotic penetration into pancreatic necrosis [PDF]

HPB, 2006
Infection of pancreatic necrosis is the most dangerous complication of acute necrotizing pancreatitis. Infection is undoubtedly caused by the endogenous flora of the host. This is why prophylaxis with a broad-spectrum antibiotic is considered an effective procedure.
Otto, W., Komorzycki, K., Krawczyk, M.
openaire   +2 more sources

Mucus polymer concentration and in vivo adaptation converge to define the antibiotic response of Pseudomonas aeruginosa during chronic lung infection

mBio
The airway milieu of individuals with muco-obstructive airway diseases (MADs) is defined by the accumulation of dehydrated mucus due to hyperabsorption of airway surface liquid and defective mucociliary clearance. Pathological mucus becomes progressively
Matthew A. Greenwald, Suzanne L. Meinig, Lucas M. Plott, Cristian Roca, Matthew G. Higgs, Nicholas P. Vitko, Matthew R. Markovetz, Kaitlyn R. Rouillard, Jerome Carpenter, Mehmet Kesimer, David B. Hill, Jonathan C. Schisler, Matthew C. Wolfgang   +12 more
doaj   +1 more source

The importance of bismuth-containing quadruple therapy in Helicobacter pylori eradication in an era of increasing antibiotic resistance [PDF]

Yixue xinzhi zazhi, 2020
Approximately half of the global population is infected with Helicobacter pylori (Hp). Currently, the main challenge in the field of Hp is that the antibiotic resistance of Hp is increased, leading to the decreased efficacy of regimens. The prevalence of
Yi HU, Yuan ZHUANG, Nong-Hua LYU
doaj   +1 more source

Antibiotic efficacy in the complex infection environment [PDF]

Current Opinion in Microbiology, 2018
Accurate prediction of antimicrobial efficacy is essential for successful treatment of bacterial infection. Beyond genetically encoded mechanisms of antibiotic resistance, the determinants of antibiotic susceptibility during infection remain poorly understood, and treatment failure is common.
L, Radlinski, B P, Conlon
openaire   +2 more sources

Efficacy of a Homeopathic Complex (Masta-forte+Actino Cure) and Antibiotics in Treatment of Bovine Clinical Mastitis

International Journal of Bio-Resource and Stress Management, 2023
The present study was aimed to treat bovine mastitis with homeopathic remedies Masta-forte+Actino Cure along with antibiotic therapy. A total 160 animals suffering from clinical bovine mastitis were used for study.
H. R. Parsani, K. P. Shyma, J. A. Patel, N. R. Chaudhary, M. K. Patel   +4 more
doaj   +1 more source