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The porin and the permeating antibiotic: a selective diffusion barrier in Gram-negative bacteria [PDF]

Nature Reviews Microbiology, 2008
Gram-negative bacteria are responsible for a large proportion of antibiotic resistant bacterial diseases. These bacteria have a complex cell envelope that comprises an outer membrane and an inner membrane that delimit the periplasm.
Mathias Winterhalter
exaly   +2 more sources

Effect of temperature on Escherichia coli bloodstream infection in a nationwide population-based study of incidence and resistance

Antimicrobial Resistance and Infection Control, 2022
Background The incidence of Escherichia coli bloodstream infections (BSI) is high and increasing. We aimed to describe the effect of season and temperature on the incidence of E. coli BSI and antibiotic-resistant E.
Sarah F. Feldman, Elizabeth Temkin, Liat Wulffhart, Amir Nutman, Vered Schechner, Pnina Shitrit, Racheli Shvartz, Mitchell J. Schwaber, Yehuda Carmeli   +8 more
doaj   +1 more source

A framework for identifying the recent origins of mobile antibiotic resistance genes

Communications Biology, 2021
Ebmeyer and colleagues developed a genomic framework for identification and scrutiny of the origins of antibiotic resistance genes. Using data scoured from the literature and publicly available genomes, their results indicate that only 81% of previously ...
Stefan Ebmeyer, Erik Kristiansson, D. G. Joakim Larsson   +2 more
doaj   +1 more source

Discovery of a novel integron-borne aminoglycoside resistance gene present in clinical pathogens by screening environmental bacterial communities

Microbiome, 2020
Background New antibiotic resistance determinants are generally discovered too late, long after they have irreversibly emerged in pathogens and spread widely.
Maria-Elisabeth Böhm, Mohammad Razavi, Nachiket P. Marathe, Carl-Fredrik Flach, D. G. Joakim Larsson   +4 more
doaj   +1 more source

A Novel, Integron-Regulated, Class C β-Lactamase

Antibiotics, 2020
AmpC-type β-lactamases severely impair treatment of many bacterial infections, due to their broad spectrum (they hydrolyze virtually all β-lactams, except fourth-generation cephalosporins and carbapenems) and the increasing incidence of plasmid-
Maria-Elisabeth Böhm, Mohammad Razavi, Carl-Fredrik Flach, D. G. Joakim Larsson   +3 more
doaj   +1 more source

Model Systems of Human Intestinal Flora, to Set Acceptable Daily Intakes of Antimicrobial Residues [PDF]

, 2000
The veterinary use of antimicrobial drugs in food producing animals may result in residues in food, that might modify the consumer gut flora. This review compares three model systems that maintain a complex flora of human origin: (i) human flora ...
Cemiglia CE, Corpet DE, Corpet DE Antibiotic residues and drug resistance in human intestinal flora, Corpet DE Antibiotic resistance from food, Corpet DE Current status of models for testing antibiotic residues, Freter R, Licht TR, Rollins LD, Tancrede C, Vollaard El   +9 more
core   +2 more sources

The Association between Insertion Sequences and Antibiotic Resistance Genes

mSphere, 2020
Insertion sequences (ISs) are abundant mobile genetic elements on bacterial genomes, responsible for mobilization of many genes, including antibiotic resistance genes (ARGs).
Mohammad Razavi, Erik Kristiansson, Carl-Fredrik Flach, D. G. Joakim Larsson   +3 more
doaj   +1 more source

Comparative Analysis of Genetic Determinants Encoding Cadmium, Arsenic, and Benzalkonium Chloride Resistance in Listeria monocytogenes of Human, Food, and Environmental Origin

Frontiers in Microbiology, 2021
Environmental adaptation of Listeria monocytogenes is a complex process involving various mechanisms that can contribute to their survival in the environment, further spreading throughout the food chain and the development of listeriosis. The aim of this
Tereza Gelbicova, Martina Florianova, Lucie Hluchanova, Lucie Hluchanova, Alžběta Kalova, Kristýna Korena, Nicol Strakova, Renáta Karpiskova, Renáta Karpiskova   +8 more
doaj   +1 more source

Multiplex lateral flow immunochromatographic assay is an effective method to detect carbapenemases without risk of OXA-48-like cross reactivity

Annals of Clinical Microbiology and Antimicrobials, 2021
Background It is essential to detect carriers of carbapenemase-producing Enterobacterales in order to implement infection control measures. The objectives of this study was to evaluate the NG-Test® CARBA 5 (CARBA 5) assay for detection of five ...
Hadas Kon, Shirin Abramov, Sammy Frenk, David Schwartz, Ohad Shalom, Amos Adler, Yehuda Carmeli, Jonathan Lellouche   +7 more
doaj   +1 more source

Colistin Dependency among Colistin-Heteroresistant Acinetobacter baumannii Isolates

Microorganisms, 2021
Colistin dependent (CD) isolates are dependent on colistin for optimal growth. Here we aimed to systematically determine the emergence of CD among colistin-heteroresistant carbapenem-resistant Acinetobacter baumannii (CRAB) isolates. We also examined the
Hadas Kon, Amichay Hameir, Elizabeth Temkin, Alona Keren-Paz, David Schwartz, Vered Schechner, Yehuda Carmeli   +6 more
doaj   +1 more source