A Scientific Roadmap for Antibiotic Discovery: A Sustained and Robust Pipeline of New Antibacterial Drugs and Therapies is Critical to Preserve Public Health [PDF]
In recent decades, the discovery and development of new antibiotics have slowed dramatically as scientific barriers to drug discovery, regulatory challenges, and diminishing returns on investment have led major drug companies to scale back or abandon ...
Allan Coukell+5 more
core
In vivo interspecies dissemination of IncM2-type blaNDM-1 carrying plasmid
The gastrointestinal tract is a unique ecological niche with a high abundance of various Enterobacterales in close proximity. This allows the exchange of mobile genetic elements that carry resistance determinants.
Mor N. Lurie-Weinberger+8 more
doaj +1 more source
Microbial Communities of the Providence River [PDF]
The Providence River has been industrialized for over one-hundred years. Industries such as oil storage and metal recycling facilities have left high levels of pollutant metals, including lead (Pb), in the soil and water.
Kratch, Jacqueline
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Microarray-based Detection of Antibiotic Resisteance Genes in Salmonella [PDF]
In the presented study, 143 Salmonella isolates belonging to 26 different serovars were screened for the presence of antibiotic resistance genes by microarray analysis.
Aarts, H.J.M., Hoek, A.H.A.M., van
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Antibiotic susceptibility, heteroresistance, and updated treatment strategies in helicobacter pylori infection [PDF]
In this review, we discuss the problem of antibiotic resistance, heteroresistance, the utility of cultures and antibiotic susceptibility tests in Helicobacter pylori (Hp) eradication, as well as the updated treatment strategies for this infection.
De Angelis, Massimiliano+3 more
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Transfer of antibiotic resistance in Staphylococcus aureus [PDF]
Staphylococcus aureus is a serious human pathogen with remarkable adaptive powers. Antibiotic-resistant clones rapidly emerge mainly by acquisition of antibiotic-resistance genes from other S. aureus strains or even from other genera.
Haaber, Jakob+2 more
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Cross-Resistance Studies and Antibiotic Identification [PDF]
E. O. Stapley
openalex +1 more source
Study of Molecular Mechanism of Antibiotic susceptibility against Polymicrobial Oral infection [PDF]
Introduction- Antibiotic to treat dental caries infection are routinely prescribed. Bacteria have increased resistance to the currently recommended antibiotics.
Deepak Dwivedi
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Induced Resistance of Staphylococcus aureus to Various Antibiotics [PDF]
John W. Klimek+2 more
openalex +1 more source
The Yield of One vs. Two Blood Cultures in Children: Under-Detection and Over-Testing
We aimed to determine whether obtaining two blood cultures (BCs) instead of one improved the detection of bloodstream infections (BSIs) in children. For this descriptive study, we used surveillance data collected in 2019–2021 from all Israeli hospitals ...
Anat Zalmanovich+3 more
doaj +1 more source