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ANTIBIOTIC RESISTANCE

Journal of Research in Pharmacy, 2023
Antibiotics are medicines used to prevent and treat bacterial infections. Antibiotic resistance occurs when the response of bacteria to medicines. Unfortunately nowadays the emergence of resistance among bacterial pathogens is a major public worldwide health problem.
Pervin Rayaman
semanticscholar   +4 more sources

Antibiotic resistance in the patient with cancer: Escalating challenges and paths forward

Ca-A Cancer Journal for Clinicians, 2021
Infection is the second leading cause of death in patients with cancer. Loss of efficacy in antibiotics due to antibiotic resistance in bacteria is an urgent threat against the continuing success of cancer therapy.
Amila K Nanayakkara, Vance G Fowler, Kevin Outterson   +2 more
exaly   +2 more sources

Mechanisms of antibiotic resistance [PDF]

Frontiers in Microbiology, 2015
Antibiotics represent one of the most successful forms of therapy in medicine. But the efficiency of antibiotics is compromised by a growing number of antibiotic-resistant pathogens.
Jun Lin, K. Nishino, M. Roberts, M. Tolmasky, R. Aminov, Lixin Zhang   +5 more
semanticscholar   +6 more sources

ANTIBIOTIC RESISTANCE [PDF]

Critical Care Clinics, 1998
Antibiotic resistance is a worldwide concern. Over the past several decades, antibiotic resistance has increased to many respiratory pathogens as well as aerobic gram-negative bacilli. Recently, methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus (VRE) have become important hospital pathogens.
A J, Smith, K, Roy, J, Gibson, J, Bagg
  +11 more sources

CARD 2023: expanded curation, support for machine learning, and resistome prediction at the Comprehensive Antibiotic Resistance Database

Nucleic Acids Res., 2022
The Comprehensive Antibiotic Resistance Database (CARD; card.mcmaster.ca) combines the Antibiotic Resistance Ontology (ARO) with curated AMR gene (ARG) sequences and resistance-conferring mutations to provide an informatics framework for annotation and ...
Brian P. Alcock, William Huynh, Romeo Chalil, Keaton W. Smith, A. Raphenya, Mateusz A Wlodarski, Arman Edalatmand, Aaron Petkau, Sohaib A Syed, Kara K. Tsang, Sheridan J. C. Baker, Mugdha Dave, Madeline C. McCarthy, Karyn M. Mukiri, Jalees A. Nasir, Bahar Golbon, Hamna Imtiaz, Xingjian Jiang, Komal Kaur, Megan Kwong, Zi Cheng Liang, Keyu C Niu, Prabakar Shan, Jasmine Y J Yang, Kristen L. Gray, Gemma Hoad, Baofeng Jia, Timsy Bhando, Lindsey A. Carfrae, Maya A. Farha, S. French, Rodion Gordzevich, Kenneth Rachwalski, Megan M. Tu, E. Bordeleau, Damion M. Dooley, E. Griffiths, Haley L. Zubyk, E. Brown, F. Maguire, R. Beiko, W. Hsiao, F. Brinkman, G. Domselaar, A. McArthur   +44 more
semanticscholar   +1 more source

Antibiotic resistance

Journal of Infection and Public Health, 2017
Antimicrobial resistance in bacterial pathogens is a challenge that is associated with high morbidity and mortality. Multidrug resistance patterns in Gram-positive and -negative bacteria are difficult to treat and may even be untreatable with conventional antibiotics.
Marianne Frieri, Krishan Kumar, Anthony Boutin   +2 more
  +7 more sources

Origin of Antibiotics and Antibiotic Resistance, and Their Impacts on Drug Development: A Narrative Review

Pharmaceuticals, 2023
Antibiotics have revolutionized medicine, saving countless lives since their discovery in the early 20th century. However, the origin of antibiotics is now overshadowed by the alarming rise in antibiotic resistance.
Ghazala Muteeb, M. Rehman, Moayad Shahwan, Mohammad Aatif   +3 more
semanticscholar   +1 more source

Antibiotic resistance: The challenges and some emerging strategies for tackling a global menace

Journal of clinical laboratory analysis (Print), 2022
Antibiotic resistance is currently the most serious global threat to the effective treatment of bacterial infections. Antibiotic resistance has been established to adversely affect both clinical and therapeutic outcomes, with consequences ranging from ...
David Chinemerem Nwobodo, M. Ugwu, Clement Oliseloke Anie, M. T. Al-Ouqaili, Joseph Chinedu Ikem, Uchenna Victor Chigozie, M. Saki   +6 more
semanticscholar   +1 more source

Effect of temperature on Escherichia coli bloodstream infection in a nationwide population-based study of incidence and resistance

Antimicrobial Resistance and Infection Control, 2022
Background The incidence of Escherichia coli bloodstream infections (BSI) is high and increasing. We aimed to describe the effect of season and temperature on the incidence of E. coli BSI and antibiotic-resistant E.
Sarah F. Feldman, Elizabeth Temkin, Liat Wulffhart, Amir Nutman, Vered Schechner, Pnina Shitrit, Racheli Shvartz, Mitchell J. Schwaber, Yehuda Carmeli   +8 more
doaj   +1 more source

Metabolism and signaling crosstalk in glioblastoma progression and therapy resistance

Molecular Oncology, EarlyView., 2023
Glioblastoma is one of the most lethal human cancers with no effective treatment nowadays. Here, we review the increasing amount of evidence supporting the connection between cell signaling deregulation and metabolic reprogramming as a key event in glioblastoma resistance to cancer therapy.
Laura Zarzuela, Raúl V. Durán, Mercedes Tomé   +2 more
wiley   +1 more source