Results 31 to 40 of about 545,691 (312)

Vaccines in the fight against antimicrobial resistance – from evidence to policy - perspectives from South Africa

International Journal of Infectious Diseases
Introduction: The rising prevalence of drug-resistant infections presents a challenge to modern medicine by limiting life-saving therapeutic options, especially for those who cannot afford more expensive second-and third-line antibiotics, and ...
Dr Elloise Du Toit, Dr Erta Kalanxhi, Prof Adrian Brink, Ms Isabella Impalli   +3 more
doaj   +1 more source

Unraveling the Diversity of Co-Colonization by CPE

Microorganisms, 2022
Antibiotic-resistant bacteria, and more specifically, carbapenem-producing Enterobacterales (CPE) strains, are increasing worldwide. Despite their growing prevalence, in most high-income countries, the detection of CPE is still considered a low-frequency
Gabrielle Levi, Mor Lurie-Weinberger, Alona Keren-Paz, Antoine O. Andremont, David Schwartz, Yehuda Carmeli   +5 more
doaj   +1 more source

Antibiotic resistance in European wastewater treatment plants mirrors the pattern of clinical antibiotic resistance prevalence

, 2019
Integrated antibiotic resistance (AR) surveillance is one of the objectives of the World Health Organization global action plan on antimicrobial resistance. Urban wastewater treatment plants (UWTPs) are among the most import- ant receptors and sources
Narciso-da-Rocha, Carlos, Stedtfeld, Robert D., Sorum, Henning, Vaz-Moreira, Ivone, O_Sullivan, Kristin, Walsh, Fiona, Do, Thi Thuy, Cacace, Damlano, Henriques, Isabel, Sheng, Hongjie, Giustina, Saulo Varela Della, Virta, Marko, Pärnänen, Katariina M. M., Elpers, Christian, O’Sullivan, Kristin, Thuy Do, Thi, Luis Martinez, Jose, Martinez, Jose Luis, O'Sullivan, Kristin, Karkman, Antti, Michael, Stella G, Fatta-Kassinos, Despo, Sørum, Henning, Kneis, David, Jaeger, Thomas, Rodriguez-Mozaz, Sara, Berendonk, Thomas U., Cacace, Damiano, Michael, Stella G., Manaia, Célia M., Parnanen, Katariina MM, Tiedje, James M., Varela Della Giustina, Saulo, Michael-Kordatou, Irene, Schwartz, Thomas   +34 more
core   +1 more source

Active surveillance for carbapenem-resistant Acinetobacter baumannii (CRAB) carriage

Microbiology Spectrum, 2023
Carbapenem-resistant Acinetobacter baumannii (CRAB) poses a significant threat in healthcare settings, necessitating robust infection control measures. To identify the most effective sampling method for CRAB carriage detection, we conducted a comparative
Amir Nutman, Gabrielle D. Levi, Alona Keren-Paz, David Schwartz, Samira Masarwa, Vered Schechner, Yehuda Carmeli   +6 more
doaj   +1 more source

New antibiotics for antibiotic-resistant bacteria [PDF]

F1000 Biology Reports, 2009
The need for new antibiotics to effectively treat antibiotic-resistant infections remains unfulfilled. Despite the well-publicised concern over this issue, only two novel antibiotic classes have been introduced in the past 20 years alongside several new agents of existing classes.
Stubbings, William, Labischinski, Harald
openaire   +2 more sources

Managing pollution from antibiotics manufacturing: charting actors, incentives and disincentives

Environmental Health, 2019
Background Emissions of high concentrations of antibiotics from manufacturing sites select for resistant bacteria and may contribute to the emergence of new forms of resistance in pathogens. Many scientists, industry, policy makers and other stakeholders
Niels Nijsingh, Christian Munthe, D. G. Joakim Larsson   +2 more
doaj   +1 more source

Antibiotic-Selected Gene Amplification Heightens Metal Resistance

mBio, 2021
To inhibit bacterial transmission and infection, health care facilities use bactericidal metal coatings to prevent colonization of surfaces and implanted devices.
David A. Hufnagel, Jacob E. Choby, Samantha Hao, Anders F. Johnson, Eileen M. Burd, Charles Langelier, David S. Weiss   +6 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Correction to: Managing pollution from antibiotics manufacturing: charting actors, incentives and disincentives

Environmental Health, 2019
Following publication of the original article [1], the author explained that there are multiple errors in the original ...
Niels Nijsingh, Christian Munthe, D. G. Joakim Larsson   +2 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source