Results 31 to 40 of about 819,197 (307)

Sewage effluent from an Indian hospital harbors novel carbapenemases and integron-borne antibiotic resistance genes

Microbiome, 2019
Background Hospital wastewaters contain fecal material from a large number of individuals, of which many are undergoing antibiotic therapy. It is, thus, plausible that hospital wastewaters could provide opportunities to find novel carbapenemases and ...
Nachiket P. Marathe, Fanny Berglund, Mohammad Razavi, Chandan Pal, Johannes Dröge, Sharvari Samant, Erik Kristiansson, D. G. Joakim Larsson   +7 more
doaj   +1 more source

OXA-900, a Novel OXA Sub-Family Carbapenemase Identified in Citrobacter freundii, Evades Detection by Commercial Molecular Diagnostics Tests

Microorganisms, 2021
Using whole-genome sequencing and cloning of the target gene, we identified blaOXA-900 carbapenemase, a novel blaOXA belonging to a distant and distinct sub-family of blaOXA-48-like. The plasmid-mediated gene was identified in a C.
Sammy Frenk, Nadya Rakovitsky, Hadas Kon, Reut Rov, Shirin Abramov, Mor Nadia Lurie-Weinberger, David Schwartz, Erica Pinco, Jonathan Lellouche, Yehuda Carmeli   +9 more
doaj   +1 more source

A degenerate PCR-based strategy as a means of identifying homologues of aminoglycoside and ß-lactam resistance genes in the gut microbiota [PDF]

, 2014
peer-reviewedBackground: The potential for the human gut microbiota to serve as a reservoir for antibiotic resistance genes has been the subject of recent discussion. However, this has yet to be investigated using a rapid PCR-based approach.
Cotter, Paul D., Fitzgerald, Gerald F, Fouhy, Fiona, Ross, R Paul, STANTON, CATHERINE   +4 more
core   +1 more source

Occurrence, Typing, and Resistance Genes of ESBL/AmpC-Producing Enterobacterales in Fresh Vegetables Purchased in Central Israel

Antibiotics, 2023
Beta-lactam resistance can lead to increased mortality, higher healthcare expenses, and limited therapeutic options. The primary mechanism of beta-lactam resistance is the production of extended-spectrum beta-lactamases (ESBL) and AmpC beta-lactamases ...
Hadas Kon, Mor Lurie-Weinberger, Adi Cohen, Liat Metsamber, Alona Keren-Paz, David Schwartz, Yehuda Carmeli, Vered Schechner   +7 more
doaj   +1 more source

Carbapenem-Resistant Klebsiella pneumoniae Exhibiting Clinically Undetected Colistin Heteroresistance Leads to Treatment Failure in a Murine Model of Infection

mBio, 2018
Antibiotic resistance is a growing crisis and a grave threat to human health. It is projected that antibiotic-resistant infections will lead to 10 million annual deaths worldwide by the year 2050.
Victor I. Band, Sarah W. Satola, Eileen M. Burd, Monica M. Farley, Jesse T. Jacob, David S. Weiss   +5 more
doaj   +1 more source

Two pandemics: the COVID-19 pandemic’s impact on future AMR collaboration in Europe

Humanities & Social Sciences Communications, 2023
Based on 117 responses to a web survey in 29 European countries and interviews with bureaucrats in managerial positions, this paper investigates how people working professionally with antimicrobial resistance (AMR) assess the impact of the COVID-19 ...
Elina Lampi, Daniel Carelli, Jon Pierre, Björn Rönnerstrand   +3 more
doaj   +1 more source

Antibody-mediated cross-linking of gut bacteria hinders the spread of antibiotic resistance [PDF]

, 2019
The body is home to a diverse microbiota, mainly in the gut. Resistant bacteria are selected for by antibiotic treatments, and once resistance becomes widespread in a population of hosts, antibiotics become useless. Here, we develop a multiscale model of
Bansept, Florence, Bitbol, Anne-Florence, Loverdo, Claude, Marrec, Loïc   +3 more
core   +2 more sources

Does reduced usage of antibiotics in livestock production mitigate the spread of antibiotic resistance in soil, earthworm guts, and the phyllosphere? [PDF]

, 2020
The overuse of antibiotics in animal husbandry is widespread and believed to significantly contribute to the selection of antibiotic resistance genes (ARGs) in animals.
Daniell, Tim, Giles, Madeline, Neilson, Roy, Yang, Xiao-Ru, Zhou, Shu-Yi-Dan, Zhu, Dong   +5 more
core   +3 more sources

Limited association between disinfectant use and either antibiotic or disinfectant susceptibility of Escherichia coli in both poultry and pig husbandry [PDF]

, 2019
Background Farm disinfectants are widely used in primary production, but questions have been raised if their use can select for antimicrobial resistance.
De Reu, Koen, Dewulf, Jeroen, Maertens, Helder, Meyer, Evelyne, Van Coillie, Els   +4 more
core   +2 more sources

Discovery of the fourth mobile sulfonamide resistance gene

Microbiome, 2017
Background Over the past 75 years, human pathogens have acquired antibiotic resistance genes (ARGs), often from environmental bacteria. Integrons play a major role in the acquisition of antibiotic resistance genes.
Mohammad Razavi, Nachiket P. Marathe, Michael R. Gillings, Carl-Fredrik Flach, Erik Kristiansson, D. G. Joakim Larsson   +5 more
doaj   +1 more source