Results 11 to 20 of about 716,706 (240)
Antibiotic Resistance of Bacteria [PDF]
BioMed Research International, 2015 Antibiotic resistance of bacteria and other microorganisms is one of the most serious and grievous challenges of the twenty-first century. The life-saving drugs, which held a great deal of promises during the 1940s to eradicate all the infectious life-threatening diseases in the world, have ceased to work, because of the increasing emergence of ...
Chattopadhyay, Madhab K. +4 more
openaire +3 more sources
Wildlife and Antibiotic Resistance
Frontiers in Cellular and Infection Microbiology, 2022 Antibiotic resistance is a major human health problem. While health care facilities are main contributors to the emergence, evolution and spread of antibiotic resistance, other ecosystems are involved in such dissemination. Wastewater, farm animals and pets have been considered important contributors to the development of antibiotic resistance. Herein,
Pablo Laborda +8 more
openaire +5 more sources
Comparative transcriptomics of multidrug-resistant Acinetobacter baumannii in response to antibiotic treatments [PDF]
, 2018 Multidrug-resistant Acinetobacter baumannii, a major hospital-acquired pathogen, is a serious health threat and poses a great challenge to healthcare providers.
Chan, Ting-Fung +8 more
core +2 more sources
Antibody-mediated cross-linking of gut bacteria hinders the spread of antibiotic resistance [PDF]
, 2019 The body is home to a diverse microbiota, mainly in the gut. Resistant bacteria are selected for by antibiotic treatments, and once resistance becomes widespread in a population of hosts, antibiotics become useless. Here, we develop a multiscale model of
Bansept, Florence +3 more
core +2 more sources
Cell, 2018 Bacterial mechanisms of drug resistance operate at sequential lines of defense tackling drug at entry, accumulation, target binding, or downstream toxicity. These mechanisms are encoded by genomic changes ranging in scale from point mutations, through assembly of preexisting genetic elements, to horizontal import of genes from the environment.
Idan Yelin, Roy Kishony
openaire +3 more sources
Antibiotic resistance in the environment [PDF]
Nature Reviews Microbiology, 2021 Antibiotic resistance is a global health challenge, involving the transfer of bacteria and genes between humans, animals and the environment. Although multiple barriers restrict the flow of both bacteria and genes, pathogens recurrently acquire new resistance factors from other species, thereby reducing our ability to prevent and treat bacterial ...
D. G. Joakim Larsson, Carl-Fredrik Flach
openaire +3 more sources
Carbapenemase-producing Enterobacteriaceae isolates collected in Portuguese hospitals [PDF]
, 2012 Objectives: In Portugal, little is known on carbapenemase (CARB)-producing Enterobacteriaceae. The aim of this study was to identify the resistance mechanisms of Enterobacteriaceae isolates, identified at hospital laboratories as carbapenem (CA) non ...
Antibiotic Resistance Surveillance Program in Portugal (ARSIP) +4 more
core +1 more source
Whole-Genome Sequencing and Concordance Between Antimicrobial Susceptibility Genotypes and Phenotypes of Bacterial Isolates Associated with Bovine Respiratory Disease. [PDF]
, 2017 Extended laboratory culture and antimicrobial susceptibility testing timelines hinder rapid species identification and susceptibility profiling of bacterial pathogens associated with bovine respiratory disease, the most prevalent cause of cattle ...
Abdo, Zaid +13 more
core +2 more sources
Restrictive antibiotic stewardship associated with reduced hospital mortality in gram-negative infection [PDF]
, 2017 Introduction: Antimicrobial stewardship has an important role in the control of Clostridium difficile infection (CDI) and antibiotic resistance. An important component of UK stewardship interventions is the restriction of broad-spectrum beta-lactam ...
Helps, Alieen +5 more
core +1 more source
Characterization of wild and captive baboon gut microbiota and their antibiotic resistomes [PDF]
, 2018 Antibiotic exposure results in acute and persistent shifts in the composition and function of microbial communities associated with vertebrate hosts.
Boolchandani, Manish +9 more
core +2 more sources