Results 11 to 20 of about 4,390,699 (400)

Antibiotic resistance in the environment [PDF]

Nature Reviews Microbiology, 2021
Antibiotic resistance is a global health challenge, involving the transfer of bacteria and genes between humans, animals and the environment. Although multiple barriers restrict the flow of both bacteria and genes, pathogens recurrently acquire new ...
D G Joakim Larsson, Carl-Fredrik Flach
exaly   +5 more sources

Antibiotic resistance in the patient with cancer: Escalating challenges and paths forward

Ca-A Cancer Journal for Clinicians, 2021
Infection is the second leading cause of death in patients with cancer. Loss of efficacy in antibiotics due to antibiotic resistance in bacteria is an urgent threat against the continuing success of cancer therapy.
Amila K Nanayakkara, Vance G Fowler, Kevin Outterson   +2 more
exaly   +2 more sources

The porin and the permeating antibiotic: a selective diffusion barrier in Gram-negative bacteria [PDF]

Nature Reviews Microbiology, 2008
Gram-negative bacteria are responsible for a large proportion of antibiotic resistant bacterial diseases. These bacteria have a complex cell envelope that comprises an outer membrane and an inner membrane that delimit the periplasm.
Mathias Winterhalter
exaly   +2 more sources

Molecular mechanisms of antibiotic resistance revisited

Nature Reviews Microbiology, 2022
Elizabeth Darby, Eleftheria Trampari
exaly   +2 more sources

ANTIBIOTIC RESISTANCE [PDF]

Critical Care Clinics, 1998
Antibiotic resistance is a worldwide concern. Over the past several decades, antibiotic resistance has increased to many respiratory pathogens as well as aerobic gram-negative bacilli. Recently, methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus (VRE) have become important hospital pathogens.
A J, Smith, K, Roy, J, Gibson, J, Bagg
  +11 more sources

Antibiotic resistance

Journal of Infection and Public Health, 2017
Antimicrobial resistance in bacterial pathogens is a challenge that is associated with high morbidity and mortality. Multidrug resistance patterns in Gram-positive and -negative bacteria are difficult to treat and may even be untreatable with conventional antibiotics.
Marianne Frieri, Krishan Kumar, Anthony Boutin   +2 more
  +7 more sources

CARD 2023: expanded curation, support for machine learning, and resistome prediction at the Comprehensive Antibiotic Resistance Database

Nucleic Acids Res., 2022
The Comprehensive Antibiotic Resistance Database (CARD; card.mcmaster.ca) combines the Antibiotic Resistance Ontology (ARO) with curated AMR gene (ARG) sequences and resistance-conferring mutations to provide an informatics framework for annotation and ...
Brian P. Alcock, William Huynh, Romeo Chalil, Keaton W. Smith, A. Raphenya, Mateusz A Wlodarski, Arman Edalatmand, Aaron Petkau, Sohaib A Syed, Kara K. Tsang, Sheridan J. C. Baker, Mugdha Dave, Madeline C. McCarthy, Karyn M. Mukiri, Jalees A. Nasir, Bahar Golbon, Hamna Imtiaz, Xingjian Jiang, Komal Kaur, Megan Kwong, Zi Cheng Liang, Keyu C Niu, Prabakar Shan, Jasmine Y J Yang, Kristen L. Gray, Gemma Hoad, Baofeng Jia, Timsy Bhando, Lindsey A. Carfrae, Maya A. Farha, S. French, Rodion Gordzevich, Kenneth Rachwalski, Megan M. Tu, E. Bordeleau, Damion M. Dooley, E. Griffiths, Haley L. Zubyk, E. Brown, F. Maguire, R. Beiko, W. Hsiao, F. Brinkman, G. Domselaar, A. McArthur   +44 more
semanticscholar   +1 more source

Origin of Antibiotics and Antibiotic Resistance, and Their Impacts on Drug Development: A Narrative Review

Pharmaceuticals, 2023
Antibiotics have revolutionized medicine, saving countless lives since their discovery in the early 20th century. However, the origin of antibiotics is now overshadowed by the alarming rise in antibiotic resistance.
Ghazala Muteeb, M. Rehman, Moayad Shahwan, Mohammad Aatif   +3 more
semanticscholar   +1 more source

Horizontal Gene Transfer of Antibiotic Resistance Genes in Biofilms

Antibiotics, 2023
Most bacteria attach to biotic or abiotic surfaces and are embedded in a complex matrix which is known as biofilm. Biofilm formation is especially worrisome in clinical settings as it hinders the treatment of infections with antibiotics due to the ...
C. Michaelis, E. Grohmann
semanticscholar   +1 more source

Bacterial Antibiotic Resistance: The Most Critical Pathogens

Pathogens, 2023
Antibiotics primarily act on bacterial growth by eliminating bacteria or preventing them from reproducing and spreading [...].
C. Biondo
semanticscholar   +1 more source