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Antibiotic resistance in the environment
Nature Reviews Microbiology, 2021 Antibiotic resistance is a global health challenge, involving the transfer of bacteria and genes between humans, animals and the environment. Although multiple barriers restrict the flow of both bacteria and genes, pathogens recurrently acquire new ...
D G Joakim Larsson, Carl-Fredrik Flach
exaly +2 more sources
Antibiotic resistance in the patient with cancer: Escalating challenges and paths forward
Ca-A Cancer Journal for Clinicians, 2021 Infection is the second leading cause of death in patients with cancer. Loss of efficacy in antibiotics due to antibiotic resistance in bacteria is an urgent threat against the continuing success of cancer therapy.
Amila K Nanayakkara +2 more
exaly +2 more sources
The porin and the permeating antibiotic: a selective diffusion barrier in Gram-negative bacteria [PDF]
Nature Reviews Microbiology, 2008 Gram-negative bacteria are responsible for a large proportion of antibiotic resistant bacterial diseases. These bacteria have a complex cell envelope that comprises an outer membrane and an inner membrane that delimit the periplasm.
Mathias Winterhalter
exaly +2 more sources
Molecular mechanisms of antibiotic resistance revisited
Nature Reviews Microbiology, 2022 Elizabeth Darby, Eleftheria Trampari
exaly +2 more sources
Critical Care Clinics, 1998 Antibiotic resistance is an increasing problem in many parts of the world. Antibiotic resistance has been associated with the use of some antibiotics but not with others. Due to the overuse of antibiotics with a high resistance potential, there has been an increase of resistance with certain bacteria, e.g., Staphylococcus aureus, Pseudomonas aeruginosa
A J, Smith, K, Roy, J, Gibson, J, Bagg
+9 more sources
Nucleic Acids Res., 2022 The Comprehensive Antibiotic Resistance Database (CARD; card.mcmaster.ca) combines the Antibiotic Resistance Ontology (ARO) with curated AMR gene (ARG) sequences and resistance-conferring mutations to provide an informatics framework for annotation and ...
Brian P. Alcock +44 more
semanticscholar +1 more source
Pharmaceuticals, 2023 Antibiotics have revolutionized medicine, saving countless lives since their discovery in the early 20th century. However, the origin of antibiotics is now overshadowed by the alarming rise in antibiotic resistance.
Ghazala Muteeb +3 more
semanticscholar +1 more source
Resistance-resistant antibiotics [PDF]
Trends in Pharmacological Sciences, 2014 New antibiotics are needed because drug resistance is increasing while the introduction of new antibiotics is decreasing. We discuss here six possible approaches to develop 'resistance-resistant' antibiotics. First, multitarget inhibitors in which a single compound inhibits more than one target may be easier to develop than conventional combination ...
Eric, Oldfield, Xinxin, Feng
openaire +2 more sources
Microorganisms, 2023 Biofilm is complex and consists of bacterial colonies that reside in an exopolysaccharide matrix that attaches to foreign surfaces in a living organism. Biofilm frequently leads to nosocomial, chronic infections in clinical settings.
Satish Sharma +5 more
semanticscholar +1 more source
Antimicrobial Resistance and Infection Control, 2022 Background The incidence of Escherichia coli bloodstream infections (BSI) is high and increasing. We aimed to describe the effect of season and temperature on the incidence of E. coli BSI and antibiotic-resistant E.
Sarah F. Feldman +8 more
doaj +1 more source