Results 11 to 20 of about 4,451,314 (357)

CARD 2023: expanded curation, support for machine learning, and resistome prediction at the Comprehensive Antibiotic Resistance Database

open access: yesNucleic Acids Res., 2022
The Comprehensive Antibiotic Resistance Database (CARD; card.mcmaster.ca) combines the Antibiotic Resistance Ontology (ARO) with curated AMR gene (ARG) sequences and resistance-conferring mutations to provide an informatics framework for annotation and ...
Brian P. Alcock   +44 more
semanticscholar   +1 more source

Origin of Antibiotics and Antibiotic Resistance, and Their Impacts on Drug Development: A Narrative Review

open access: yesPharmaceuticals, 2023
Antibiotics have revolutionized medicine, saving countless lives since their discovery in the early 20th century. However, the origin of antibiotics is now overshadowed by the alarming rise in antibiotic resistance.
Ghazala Muteeb   +3 more
semanticscholar   +1 more source

Microbial Biofilm: A Review on Formation, Infection, Antibiotic Resistance, Control Measures, and Innovative Treatment

open access: yesMicroorganisms, 2023
Biofilm is complex and consists of bacterial colonies that reside in an exopolysaccharide matrix that attaches to foreign surfaces in a living organism. Biofilm frequently leads to nosocomial, chronic infections in clinical settings.
Satish Sharma   +5 more
semanticscholar   +1 more source

Horizontal Gene Transfer of Antibiotic Resistance Genes in Biofilms

open access: yesAntibiotics, 2023
Most bacteria attach to biotic or abiotic surfaces and are embedded in a complex matrix which is known as biofilm. Biofilm formation is especially worrisome in clinical settings as it hinders the treatment of infections with antibiotics due to the ...
C. Michaelis, E. Grohmann
semanticscholar   +1 more source

Bacterial Antibiotic Resistance: The Most Critical Pathogens

open access: yesPathogens, 2023
Antibiotics primarily act on bacterial growth by eliminating bacteria or preventing them from reproducing and spreading [...].
C. Biondo
semanticscholar   +1 more source

Quaternary ammonium disinfectants and antiseptics: tolerance, resistance and potential impact on antibiotic resistance

open access: yesAntimicrobial Resistance and Infection Control, 2023
Background Due to the substantial increase in the use of disinfectants containing quaternary ammonion compounds (QACs) in healthcare and community settings during the COVID-19 pandemic, there is increased concern that heavy use might cause bacteria to ...
J. Boyce
semanticscholar   +1 more source

Assessment of global health risk of antibiotic resistance genes

open access: yesNature Communications, 2022
Antibiotic resistance genes (ARGs) have accelerated microbial threats to human health in the last decade. Many genes can confer resistance, but evaluating the relative health risks of ARGs is complex. Factors such as the abundance, propensity for lateral
Zhenyan Zhang   +10 more
semanticscholar   +1 more source

Antibiotic resistance: The challenges and some emerging strategies for tackling a global menace

open access: yesJournal of clinical laboratory analysis (Print), 2022
Antibiotic resistance is currently the most serious global threat to the effective treatment of bacterial infections. Antibiotic resistance has been established to adversely affect both clinical and therapeutic outcomes, with consequences ranging from ...
David Chinemerem Nwobodo   +6 more
semanticscholar   +1 more source

Antibiotic Resistance in Bacteria—A Review

open access: yesAntibiotics, 2022
Background: A global problem of multi-drug resistance (MDR) among bacteria is the cause of hundreds of thousands of deaths every year. In response to the significant increase of MDR bacteria, legislative measures have widely been taken to limit or ...
R. Urban-Chmiel   +6 more
semanticscholar   +1 more source

Antibiotics and antibiotic resistance genes in agricultural soils: A systematic analysis

open access: yesCritical reviews in environmental science and technology, 2022
Misuse and overuse of antibiotics have contributed to the rise of antimicrobial resistance as one of the top public health threats. Antibiotics and antibiotic resistance genes (ARGs) are prevalent in agricultural soils due to the widespread application ...
Jie Wu   +8 more
semanticscholar   +1 more source

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