Results 41 to 50 of about 4,390,699 (400)

Genome sequences of two clinical Escherichia coli isolates harboring the novel colistin-resistance gene variants mcr-1.26 and mcr-1.27

Gut Pathogens, 2020
Background Colistin is still a widely used antibiotic in veterinary medicine although it is a last-line treatment option for hospitalized patients with infections caused by multidrug-resistant Gram-negative bacteria.
Bernd Neumann, Wiebke Rackwitz, Klaus-Peter Hunfeld, Stephan Fuchs, Guido Werner, Yvonne Pfeifer   +5 more
doaj   +1 more source

Multiplex lateral flow immunochromatographic assay is an effective method to detect carbapenemases without risk of OXA-48-like cross reactivity

Annals of Clinical Microbiology and Antimicrobials, 2021
Background It is essential to detect carriers of carbapenemase-producing Enterobacterales in order to implement infection control measures. The objectives of this study was to evaluate the NG-Test® CARBA 5 (CARBA 5) assay for detection of five ...
Hadas Kon, Shirin Abramov, Sammy Frenk, David Schwartz, Ohad Shalom, Amos Adler, Yehuda Carmeli, Jonathan Lellouche   +7 more
doaj   +1 more source

Antibiotics and antibiotic resistance genes in agricultural soils: A systematic analysis

Critical reviews in environmental science and technology, 2022
Misuse and overuse of antibiotics have contributed to the rise of antimicrobial resistance as one of the top public health threats. Antibiotics and antibiotic resistance genes (ARGs) are prevalent in agricultural soils due to the widespread application ...
Jie Wu, Jinyan Wang, Zhutao Li, Shumin Guo, Kejie Li, Pinshang Xu, Y. Ok, Davey L. Jones, Jianwen Zou   +8 more
semanticscholar   +1 more source

The impact of antibiotic use on transmission of resistant bacteria in hospitals: Insights from an agent-based model [PDF]

, 2018
Extensive antibiotic use over the years has led to the emergence and spread of antibiotic resistant bacteria (ARB). Antibiotic resistance poses a major threat to public health since for many infections antibiotic treatment is no longer effective ...
DRIVE-AB consortium, Elizabeth Temkin, Itzhak Benenson, Jonatan Almagor, Noga Fallach, Yehuda Carmeli   +5 more
core   +2 more sources

Clinically relevant mutations in core metabolic genes confer antibiotic resistance

Science, 2021
The many roads to resistance Antibiotic resistance arising from mutation is common among pathogenic bacteria. However, this process is not well understood, and most of the mutations that have been identified to confer resistance do so by modification of ...
A. Lopatkin, Sarah C. Bening, A. Manson, Jonathan M. Stokes, M. Kohanski, A. Badran, A. Earl, N. Cheney, Jason H. Yang, J. Collins   +9 more
semanticscholar   +1 more source

Antimicrobial Resistance: An Update from the Canadian Committee on Antibiotic Resistance

Canadian Journal of Infectious Diseases and Medical Microbiology, 2005
The present article is one of a series prepared by the Canadian Committee on Antibiotic Resistance (CCAR). These articles are designed to update readers on current activities intended to limit the development and transmission of antibiotic resistance
Canadian Committee on Antibiotic Resistance
doaj   +1 more source

Acinetobacter baumannii Bloodstream Infections: A Nationwide Study in Israel

Microorganisms, 2023
Acinetobacter baumannii (Ab) bloodstream infections (BSIs) are a major public health concern and associated with high mortality. We describe the nationwide incidence, antimicrobial resistance, and mortality of Ab-BSI in Israel using laboratory-based BSI ...
Amir Nutman, Elizabeth Temkin, Liat Wullfhart, Vered Schechner, Mitchell J. Schwaber, Yehuda Carmeli   +5 more
doaj   +1 more source

Sewage effluent from an Indian hospital harbors novel carbapenemases and integron-borne antibiotic resistance genes

Microbiome, 2019
Background Hospital wastewaters contain fecal material from a large number of individuals, of which many are undergoing antibiotic therapy. It is, thus, plausible that hospital wastewaters could provide opportunities to find novel carbapenemases and ...
Nachiket P. Marathe, Fanny Berglund, Mohammad Razavi, Chandan Pal, Johannes Dröge, Sharvari Samant, Erik Kristiansson, D. G. Joakim Larsson   +7 more
doaj   +1 more source

OXA-900, a Novel OXA Sub-Family Carbapenemase Identified in Citrobacter freundii, Evades Detection by Commercial Molecular Diagnostics Tests

Microorganisms, 2021
Using whole-genome sequencing and cloning of the target gene, we identified blaOXA-900 carbapenemase, a novel blaOXA belonging to a distant and distinct sub-family of blaOXA-48-like. The plasmid-mediated gene was identified in a C.
Sammy Frenk, Nadya Rakovitsky, Hadas Kon, Reut Rov, Shirin Abramov, Mor Nadia Lurie-Weinberger, David Schwartz, Erica Pinco, Jonathan Lellouche, Yehuda Carmeli   +9 more
doaj   +1 more source

Occurrence, Typing, and Resistance Genes of ESBL/AmpC-Producing Enterobacterales in Fresh Vegetables Purchased in Central Israel

Antibiotics, 2023
Beta-lactam resistance can lead to increased mortality, higher healthcare expenses, and limited therapeutic options. The primary mechanism of beta-lactam resistance is the production of extended-spectrum beta-lactamases (ESBL) and AmpC beta-lactamases ...
Hadas Kon, Mor Lurie-Weinberger, Adi Cohen, Liat Metsamber, Alona Keren-Paz, David Schwartz, Yehuda Carmeli, Vered Schechner   +7 more
doaj   +1 more source