A degenerate PCR-based strategy as a means of identifying homologues of aminoglycoside and ß-lactam resistance genes in the gut microbiota [PDF]
, 2014 peer-reviewedBackground: The potential for the human gut microbiota to serve as a reservoir for antibiotic resistance genes has been the subject of recent discussion. However, this has yet to be investigated using a rapid PCR-based approach.
Cotter, Paul D. +4 more
core +1 more source
Antibiotics and antibiotic resistance genes in agricultural soils: A systematic analysis
Critical reviews in environmental science and technology, 2022 Misuse and overuse of antibiotics have contributed to the rise of antimicrobial resistance as one of the top public health threats. Antibiotics and antibiotic resistance genes (ARGs) are prevalent in agricultural soils due to the widespread application ...
Jie Wu +8 more
semanticscholar +1 more source
Antibody-mediated cross-linking of gut bacteria hinders the spread of antibiotic resistance [PDF]
, 2019 The body is home to a diverse microbiota, mainly in the gut. Resistant bacteria are selected for by antibiotic treatments, and once resistance becomes widespread in a population of hosts, antibiotics become useless. Here, we develop a multiscale model of
Bansept, Florence +3 more
core +2 more sources
Clinically relevant mutations in core metabolic genes confer antibiotic resistance
Science, 2021 The many roads to resistance Antibiotic resistance arising from mutation is common among pathogenic bacteria. However, this process is not well understood, and most of the mutations that have been identified to confer resistance do so by modification of ...
A. Lopatkin +9 more
semanticscholar +1 more source
mBio, 2018 Antibiotic resistance is a growing crisis and a grave threat to human health. It is projected that antibiotic-resistant infections will lead to 10 million annual deaths worldwide by the year 2050.
Victor I. Band +5 more
doaj +1 more source
Two pandemics: the COVID-19 pandemic’s impact on future AMR collaboration in Europe
Humanities & Social Sciences Communications, 2023 Based on 117 responses to a web survey in 29 European countries and interviews with bureaucrats in managerial positions, this paper investigates how people working professionally with antimicrobial resistance (AMR) assess the impact of the COVID-19 ...
Elina Lampi +3 more
doaj +1 more source
Bacterial Stress Responses as Potential Targets in Overcoming Antibiotic Resistance
Microorganisms, 2022 Bacteria can be adapted to adverse and detrimental conditions that induce general and specific responses to DNA damage as well as acid, heat, cold, starvation, oxidative, envelope, and osmotic stresses.
Jirapat Dawan, Juhee Ahn
semanticscholar +1 more source
The Spread of Antibiotic Resistance Genes In Vivo Model
The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale, 2022 Infections caused by antibiotic-resistant bacteria are a major public health threat. The emergence and spread of antibiotic resistance genes (ARGs) in the environment or clinical setting pose a serious threat to human and animal health worldwide ...
Shuan Tao +4 more
semanticscholar +1 more source
Whole-Genome Sequencing and Concordance Between Antimicrobial Susceptibility Genotypes and Phenotypes of Bacterial Isolates Associated with Bovine Respiratory Disease. [PDF]
, 2017 Extended laboratory culture and antimicrobial susceptibility testing timelines hinder rapid species identification and susceptibility profiling of bacterial pathogens associated with bovine respiratory disease, the most prevalent cause of cattle ...
Abdo, Zaid +13 more
core +2 more sources
Discovery of the fourth mobile sulfonamide resistance gene
Microbiome, 2017 Background Over the past 75 years, human pathogens have acquired antibiotic resistance genes (ARGs), often from environmental bacteria. Integrons play a major role in the acquisition of antibiotic resistance genes.
Mohammad Razavi +5 more
doaj +1 more source