Unraveling the Diversity of Co-Colonization by CPE
Microorganisms, 2022 Antibiotic-resistant bacteria, and more specifically, carbapenem-producing Enterobacterales (CPE) strains, are increasing worldwide. Despite their growing prevalence, in most high-income countries, the detection of CPE is still considered a low-frequency
Gabrielle Levi +5 more
doaj +1 more source
Cell, 2018 Bacterial mechanisms of drug resistance operate at sequential lines of defense tackling drug at entry, accumulation, target binding, or downstream toxicity. These mechanisms are encoded by genomic changes ranging in scale from point mutations, through assembly of preexisting genetic elements, to horizontal import of genes from the environment.
Idan Yelin, Roy Kishony
openaire +3 more sources
The impact of antibiotic use on transmission of resistant bacteria in hospitals: Insights from an agent-based model [PDF]
, 2018 Extensive antibiotic use over the years has led to the emergence and spread of antibiotic resistant bacteria (ARB). Antibiotic resistance poses a major threat to public health since for many infections antibiotic treatment is no longer effective ...
DRIVE-AB consortium +5 more
core +1 more source
Antibiotic resistance in the environment [PDF]
Nature Reviews Microbiology, 2021 Antibiotic resistance is a global health challenge, involving the transfer of bacteria and genes between humans, animals and the environment. Although multiple barriers restrict the flow of both bacteria and genes, pathogens recurrently acquire new resistance factors from other species, thereby reducing our ability to prevent and treat bacterial ...
D. G. Joakim Larsson, Carl-Fredrik Flach
openaire +3 more sources
Exposure of ciprofloxacin-resistant Escherichia coli broiler isolates to subinhibitory concentrations of a quaternary ammonium compound does not increase antibiotic resistance gene transfer [PDF]
, 2019 Resistance to antibiotics threatens to become a worldwide health problem. An important attributing phenomenon in this context is that pathogens can acquire antibiotic resistance genes through conjugative transfer of plasmids.
De Reu, K. +5 more
core +1 more source
Discovery of the fourth mobile sulfonamide resistance gene
Microbiome, 2017 Background Over the past 75 years, human pathogens have acquired antibiotic resistance genes (ARGs), often from environmental bacteria. Integrons play a major role in the acquisition of antibiotic resistance genes.
Mohammad Razavi +5 more
doaj +1 more source
Comparative transcriptomics of multidrug-resistant Acinetobacter baumannii in response to antibiotic treatments [PDF]
, 2018 Multidrug-resistant Acinetobacter baumannii, a major hospital-acquired pathogen, is a serious health threat and poses a great challenge to healthcare providers.
Chan, Ting-Fung +8 more
core +2 more sources
Managing pollution from antibiotics manufacturing: charting actors, incentives and disincentives
Environmental Health, 2019 Background Emissions of high concentrations of antibiotics from manufacturing sites select for resistant bacteria and may contribute to the emergence of new forms of resistance in pathogens. Many scientists, industry, policy makers and other stakeholders
Niels Nijsingh +2 more
doaj +1 more source
Active surveillance for carbapenem-resistant Acinetobacter baumannii (CRAB) carriage
Microbiology Spectrum, 2023 Carbapenem-resistant Acinetobacter baumannii (CRAB) poses a significant threat in healthcare settings, necessitating robust infection control measures. To identify the most effective sampling method for CRAB carriage detection, we conducted a comparative
Amir Nutman +6 more
doaj +1 more source
Antibiotic-Selected Gene Amplification Heightens Metal Resistance
mBio, 2021 To inhibit bacterial transmission and infection, health care facilities use bactericidal metal coatings to prevent colonization of surfaces and implanted devices.
David A. Hufnagel +6 more
doaj +1 more source