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ANTIBIOTIC RESISTANCE

open access: yesJournal of Research in Pharmacy, 2023
Antibiotics are medicines used to prevent and treat bacterial infections. Antibiotic resistance occurs when the response of bacteria to medicines. Unfortunately nowadays the emergence of resistance among bacterial pathogens is a major public worldwide health problem.
openaire   +4 more sources

Carbapenemase-producing Enterobacteriaceae isolates collected in Portuguese hospitals [PDF]

open access: yes, 2012
Objectives: In Portugal, little is known on carbapenemase (CARB)-producing Enterobacteriaceae. The aim of this study was to identify the resistance mechanisms of Enterobacteriaceae isolates, identified at hospital laboratories as carbapenem (CA) non ...
Antibiotic Resistance Surveillance Program in Portugal (ARSIP)   +4 more
core   +1 more source

A degenerate PCR-based strategy as a means of identifying homologues of aminoglycoside and ß-lactam resistance genes in the gut microbiota [PDF]

open access: yes, 2014
peer-reviewedBackground: The potential for the human gut microbiota to serve as a reservoir for antibiotic resistance genes has been the subject of recent discussion. However, this has yet to be investigated using a rapid PCR-based approach.
Cotter, Paul D.   +4 more
core   +1 more source

Antimicrobial Resistance: An Update from the Canadian Committee on Antibiotic Resistance

open access: yesCanadian Journal of Infectious Diseases and Medical Microbiology, 2005
The present article is one of a series prepared by the Canadian Committee on Antibiotic Resistance (CCAR). These articles are designed to update readers on current activities intended to limit the development and transmission of antibiotic resistance
Canadian Committee on Antibiotic Resistance
doaj   +1 more source

Acinetobacter baumannii Bloodstream Infections: A Nationwide Study in Israel

open access: yesMicroorganisms, 2023
Acinetobacter baumannii (Ab) bloodstream infections (BSIs) are a major public health concern and associated with high mortality. We describe the nationwide incidence, antimicrobial resistance, and mortality of Ab-BSI in Israel using laboratory-based BSI ...
Amir Nutman   +5 more
doaj   +1 more source

Antibody-mediated cross-linking of gut bacteria hinders the spread of antibiotic resistance [PDF]

open access: yes, 2019
The body is home to a diverse microbiota, mainly in the gut. Resistant bacteria are selected for by antibiotic treatments, and once resistance becomes widespread in a population of hosts, antibiotics become useless. Here, we develop a multiscale model of
Bansept, Florence   +3 more
core   +2 more sources

CARD 2017: expansion and model-centric curation of the comprehensive antibiotic resistance database

open access: yesNucleic Acids Res., 2016
The Comprehensive Antibiotic Resistance Database (CARD; http://arpcard.mcmaster.ca) is a manually curated resource containing high quality reference data on the molecular basis of antimicrobial resistance (AMR), with an emphasis on the genes, proteins ...
Baofeng Jia   +22 more
semanticscholar   +1 more source

Acinetobacter baumannii Antibiotic Resistance Mechanisms

open access: yesPathogens, 2021
Acinetobacter baumannii is a Gram-negative ESKAPE microorganism that poses a threat to public health by causing severe and invasive (mostly nosocomial) infections linked with high mortality rates.
I. Kyriakidis   +3 more
semanticscholar   +1 more source

Sewage effluent from an Indian hospital harbors novel carbapenemases and integron-borne antibiotic resistance genes

open access: yesMicrobiome, 2019
Background Hospital wastewaters contain fecal material from a large number of individuals, of which many are undergoing antibiotic therapy. It is, thus, plausible that hospital wastewaters could provide opportunities to find novel carbapenemases and ...
Nachiket P. Marathe   +7 more
doaj   +1 more source

OXA-900, a Novel OXA Sub-Family Carbapenemase Identified in Citrobacter freundii, Evades Detection by Commercial Molecular Diagnostics Tests

open access: yesMicroorganisms, 2021
Using whole-genome sequencing and cloning of the target gene, we identified blaOXA-900 carbapenemase, a novel blaOXA belonging to a distant and distinct sub-family of blaOXA-48-like. The plasmid-mediated gene was identified in a C.
Sammy Frenk   +9 more
doaj   +1 more source

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