Antibiotic Resistance and Typhoid [PDF]
AbstractMultiple drug (antibiotic) resistance (MDR) has become a major threat to the treatment of typhoid and other infectious diseases. Since the 1970s, this threat has increased in Salmonella enterica serovar Typhi, driven in part by the emergence of successful genetic clades, such as haplotype H58, associated with the MDR phenotype. H58 S. Typhi can
Zoe A. Dyson+5 more
openaire +5 more sources
Bacterial viruses enable their host to acquire antibiotic resistance genes from neighbouring cells [PDF]
Prophages are quiescent viruses located in the chromosomes of bacteria. In the human pathogen, Staphylococcus aureus, prophages are omnipresent and are believed to be responsible for the spread of some antibiotic resistance genes.
Catalan-Moreno, Arancha+7 more
core +3 more sources
A degenerate PCR-based strategy as a means of identifying homologues of aminoglycoside and ß-lactam resistance genes in the gut microbiota [PDF]
peer-reviewedBackground: The potential for the human gut microbiota to serve as a reservoir for antibiotic resistance genes has been the subject of recent discussion. However, this has yet to be investigated using a rapid PCR-based approach.
Cotter, Paul D.+4 more
core +1 more source
We previously reported that the 14-day case fatality rate (CFR) in patients with carbapenem-resistant Acinetobacter baumannii (CRAB) bacteremia varied between infecting clones.
Amir Nutman+4 more
doaj +1 more source
Antibody-mediated cross-linking of gut bacteria hinders the spread of antibiotic resistance [PDF]
The body is home to a diverse microbiota, mainly in the gut. Resistant bacteria are selected for by antibiotic treatments, and once resistance becomes widespread in a population of hosts, antibiotics become useless. Here, we develop a multiscale model of
Bansept, Florence+3 more
core +2 more sources
Following publication of the original article [1], the author explained that there are multiple errors in the original ...
Niels Nijsingh+2 more
doaj +1 more source
Rapid identification of capsulated Acinetobacter baumannii using a density-dependent gradient test
Background Gram-negative bacterial capsules are associated with production of carbohydrates, frequently resulting in a mucoid phenotype. Infections caused by capsulated or mucoid A. baumannii are associated with increased clinical severity. Therefore, it
Hadas Kon+4 more
doaj +1 more source
Limited association between disinfectant use and either antibiotic or disinfectant susceptibility of Escherichia coli in both poultry and pig husbandry [PDF]
Background Farm disinfectants are widely used in primary production, but questions have been raised if their use can select for antimicrobial resistance.
De Reu, Koen+4 more
core +2 more sources
Does reduced usage of antibiotics in livestock production mitigate the spread of antibiotic resistance in soil, earthworm guts, and the phyllosphere? [PDF]
The overuse of antibiotics in animal husbandry is widespread and believed to significantly contribute to the selection of antibiotic resistance genes (ARGs) in animals.
Daniell, Tim+5 more
core +3 more sources
Circulating histones as clinical biomarkers in critically ill conditions
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez+17 more
wiley +1 more source