Results 51 to 60 of about 4,390,699 (400)

Comparative transcriptomics of multidrug-resistant Acinetobacter baumannii in response to antibiotic treatments [PDF]

open access: yes, 2018
Multidrug-resistant Acinetobacter baumannii, a major hospital-acquired pathogen, is a serious health threat and poses a great challenge to healthcare providers.
Chan, Ting-Fung   +8 more
core   +2 more sources

A degenerate PCR-based strategy as a means of identifying homologues of aminoglycoside and ß-lactam resistance genes in the gut microbiota [PDF]

open access: yes, 2014
peer-reviewedBackground: The potential for the human gut microbiota to serve as a reservoir for antibiotic resistance genes has been the subject of recent discussion. However, this has yet to be investigated using a rapid PCR-based approach.
Cotter, Paul D.   +4 more
core   +1 more source

Tackling antibiotic resistance [PDF]

open access: yesNature Reviews Microbiology, 2011
The development and spread of antibiotic resistance in bacteria is a universal threat to both humans and animals that is generally not preventable but can nevertheless be controlled, and it must be tackled in the most effective ways possible. To explore how the problem of antibiotic resistance might best be addressed, a group of 30 scientists from ...
Bush, Karen   +27 more
openaire   +5 more sources

Carbapenem-Resistant Klebsiella pneumoniae Exhibiting Clinically Undetected Colistin Heteroresistance Leads to Treatment Failure in a Murine Model of Infection

open access: yesmBio, 2018
Antibiotic resistance is a growing crisis and a grave threat to human health. It is projected that antibiotic-resistant infections will lead to 10 million annual deaths worldwide by the year 2050.
Victor I. Band   +5 more
doaj   +1 more source

Two pandemics: the COVID-19 pandemic’s impact on future AMR collaboration in Europe

open access: yesHumanities & Social Sciences Communications, 2023
Based on 117 responses to a web survey in 29 European countries and interviews with bureaucrats in managerial positions, this paper investigates how people working professionally with antimicrobial resistance (AMR) assess the impact of the COVID-19 ...
Elina Lampi   +3 more
doaj   +1 more source

CARD 2017: expansion and model-centric curation of the comprehensive antibiotic resistance database

open access: yesNucleic Acids Res., 2016
The Comprehensive Antibiotic Resistance Database (CARD; http://arpcard.mcmaster.ca) is a manually curated resource containing high quality reference data on the molecular basis of antimicrobial resistance (AMR), with an emphasis on the genes, proteins ...
Baofeng Jia   +22 more
semanticscholar   +1 more source

Acinetobacter baumannii Antibiotic Resistance Mechanisms

open access: yesPathogens, 2021
Acinetobacter baumannii is a Gram-negative ESKAPE microorganism that poses a threat to public health by causing severe and invasive (mostly nosocomial) infections linked with high mortality rates.
I. Kyriakidis   +3 more
semanticscholar   +1 more source

Carbapenemase-producing Enterobacteriaceae isolates collected in Portuguese hospitals [PDF]

open access: yes, 2012
Objectives: In Portugal, little is known on carbapenemase (CARB)-producing Enterobacteriaceae. The aim of this study was to identify the resistance mechanisms of Enterobacteriaceae isolates, identified at hospital laboratories as carbapenem (CA) non ...
Antibiotic Resistance Surveillance Program in Portugal (ARSIP)   +4 more
core   +1 more source

Antibiotic Resistance

open access: yesCell, 2018
Bacterial mechanisms of drug resistance operate at sequential lines of defense tackling drug at entry, accumulation, target binding, or downstream toxicity. These mechanisms are encoded by genomic changes ranging in scale from point mutations, through assembly of preexisting genetic elements, to horizontal import of genes from the environment.
Idan Yelin, Roy Kishony
openaire   +3 more sources

Antibiotic Resistance of Bacteria [PDF]

open access: yesBioMed Research International, 2015
Antibiotic resistance of bacteria and other microorganisms is one of the most serious and grievous challenges of the twenty-first century. The life-saving drugs, which held a great deal of promises during the 1940s to eradicate all the infectious life-threatening diseases in the world, have ceased to work, because of the increasing emergence of ...
Chattopadhyay, Madhab K.   +4 more
openaire   +3 more sources

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