Results 71 to 80 of about 545,691 (312)

Altered antibiotic transport in OmpC mutants isolated from a series of clinical strains of multi-drug resistant E. coli [PDF]

, 2011
This work is also partially supported by BBSRC and the Scottish Funding Council (through SULSA)Antibiotic-resistant bacteria, particularly Gram negative species, present significant health care challenges.
H. Lou, M. Chen, Susan S Black, Beis Konstantinos, Bayley Hagan, Matteo Ceccarelli, Beis, Konstantinos, Bushell, SR, Ian R Booth, Victoria A. Bamford, A. Low, Alison S Low, Bamford Victoria A., I. R. Booth, Ceccarelli Matteo, Bushell, Simon R, Ceccarelli, Matteo, Ceccarelli, M, V. A. Bamford, J. H. Naismith, James H. Naismith, James H Naismith, Booth, Ian R, Bamford, Victoria A., Naismith James H., Lou Hubing, Booth Ian R., Low, AS, Black, Susan S, Low, Alison S, Naismith, James H, Tivadar Mach, S. S. Black, Naismith, JH, H. Bayley, Low, Alison S., Mach, T, Black, Susan S., Chen, M, Bushell Simon R., Simon R. Bushell, Susan S. Black, Low Alison S., Mach Tivadar, Beis, K, Hagan Bayley, Bushell, Simon R., Min Chen, Bamford, Victoria A, Bamford, VA, K. Beis, Lou, H, Ian R. Booth, S. R. Bushell, Mach, Tivadar, Konstantinos Beis, Lou, Hubing, Booth, IR, Black Susan S., Bayley, Hagan, Alison S. Low, Naismith, James H., T. Mach, Chen Min, Booth, Ian R., Simon R Bushell, Bayley, H, Chen, Min, Victoria A Bamford, Black, SS, Hubing Lou   +70 more
core   +1 more source

Unveiling the Microbiome Landscape: A Metagenomic Study of Bacterial Diversity, Antibiotic Resistance, and Virulence Factors in the Sediments of the River Ganga, India

, 2023
The global rise in antibiotic resistance, fueled by indiscriminate antibiotic usage in medicine, aquaculture, agriculture, and the food industry, presents a significant public health challenge. Urban wastewater and sewage treatment plants have become key
Sangita Dixit, Dibyajyoti Uttameswar Behera, Ajaya Kumar Rout, Partha Sarathi Tripathy, Bijay Kumar Behera, Bhaskar Behera, Basanta Kumar Das   +6 more
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Characterisation of the vibrio cholerae antibiotic resistance var operon [PDF]

, 2007
The discovery and use of antibiotics in the chemotherapy of bacterial infections has revolutionised medicine as it is today. Unfortunately, the progressive use of antibiotics has promoted the evolution of bacterial defences against these mediators and ...
Massam-Wu, Teresa
core  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Genomic and phenotypic characterization of six multidrug-resistant Acinetobacter pittii isolates

Scientific Reports
The Acinetobacter calcoaceticus-baumannii complex is a significant cause of nosocomial infections. While A. baumannii is the most common and clinically significant member globally, recent studies suggest that A.
Nadya Rakovitsky, Mor Lurie-Weinberger, Alona Keren-Paz, Yehuda Carmeli   +3 more
doaj   +1 more source

The Future of Antibiotics and Resistance [PDF]

New England Journal of Medicine, 2013
Antibiotic resistance and the collapse of the antibiotic research-and-development pipeline continue to worsen despite our ongoing efforts. If we're to develop countermeasures that have lasting effects, new ideas that complement traditional approaches are needed.
Brad, Spellberg, John G, Bartlett, David N, Gilbert   +2 more
openaire   +2 more sources

Analysis of Antibiotic Resistance Genes (ARGs) across Diverse Bacterial Species in Shrimp Aquaculture [PDF]

There is little information available on antibiotic resistance (ABR) within shrimp aquaculture environments. The aim of this study was to investigate the presence of antibiotic resistance genes (ARGs) in shrimp farming operations in Atacames, Ecuador ...
Thomas VanderYacht, Salinas, Liseth, VanderYacht, Thomas, Tilden M. Mitchell, Graham, Jay P, Mitchell, Tilden M, Jay P. Graham, Ho, Tin, Trueba, Gabriel, Nikolina Walas, Gabriel Trueba, Liseth Salinas, Walas, Nikolina, Tin Ho   +13 more
core   +1 more source

The Role of Efflux Pumps in the Transition from Low-Level to Clinical Antibiotic Resistance

, 2020
Antibiotic resistance is on the rise and has become one of the biggest public health challenges of our time. Bacteria are able to adapt to the selective pressure exerted by antibiotics in numerous ways, including the (over)expression of efflux pumps ...
Ebbensgaard, Anna Elisabeth, Anna Elisabeth Ebbensgaard, Jakob Frimodt-Møller, Frimodt-Møller, Jakob, Løbner-Olesen, Anders, Anders Løbner-Olesen   +5 more
core   +1 more source

Antibiotic Resistance in Aquatic Systems [PDF]

, 2017
Rivers, lakes and the ocean receive antibiotic resistance genes from human environments.
Pruden, Amy, Amy Pruden, Satoru Suzuki, Tong Zhang, Virta, Marko, Zhang, Tong, Suzuki, Satoru, Marko Virta   +7 more
core   +1 more source