Results 201 to 210 of about 4,426,359 (306)

Beyond Biomimetics: Pathology‐Informed Engineering Rescues Reconstituted HDL From Inflammatory Dysfunction for Sepsis Immunotherapy

Advanced Science, EarlyView.
A pathology‐informed engineering strategy rescues reconstituted HDL from inflammatory dysfunction in sepsis. By integrating a ceria nanozyme‐celastrol coordination complex, the platform preserves HDL structure and endotoxin handling, sustains hierarchical intracellular delivery, and enhances immunoregulation across pathological models, translating ...
Han Zhou, Lei Zhang, Xingyu Cai, Jiajia Su, Guangyu Dai, Xue Chen, Hanming Wang, Jia Hua, Jianping Liu, Chunmeng Sun, Xiancheng Chen, Erhao Wang, Wenli Zhang   +12 more
wiley   +1 more source

Insights into the Mechanisms Driving the Dynamics of Antibiotic Resistance Genes During Pig Manure Composting. [PDF]

Toxics
Pan X, Cao R, Ge M, Dong M, Ben W.
europepmc   +1 more source

Design of a Novel Diamine Biosensor to Guide the Engineering of Escherichia coli for Cadaverine Overproduction

Advanced Science, EarlyView.
A high‐throughput screening platform was established by integrating an in vivo cadaverine biosensor with a fluorescence‐activated cell sorting (FACS) system. Biosensor‐driven specific exporter tuning, pathway optimization and genome‐wide target mining were conducted to maximize cadaverine production in Escherichia coli.
Jia Feng, Getao Liu, Ding Ma, Jiaxiang Yuan, Xinyi Zhang, Weihao Wang, Chen Ma, Yang Liao, Siyuan Gao, Lei Qin, Jiao Feng, Sheng Xu, Xin Wang, Kequan Chen   +13 more
wiley   +1 more source

SEVA: structural and evolutionary feature integration for predicting virulence factors and antibiotic resistance genes. [PDF]

Microbiome
Li K, Peng X, Qian X, Li S, Zhang X.
europepmc   +1 more source

TP53 Loss Elevates NF‐κB‐IFN‐β‐MHC‐Ia Signaling to Promote NK Cell Resistance in Osteosarcoma

Advanced Science, EarlyView.
TP53 loss in a transforming or osteosarcoma cell promotes cytosolic DNA accumulation, activating NF‐κB‐dependent IFN‐β production. Autocrine IFN‐β signaling increases cell‐surface HLA‐Ia expression, strengthens inhibitory KIR signaling in natural killer cells, and thereby enables the affected cell to evade NK cell‐mediated cytotoxicity.
Guihui Qin, Cheung Kwan Yeung, Ye Yi, Dejin Zheng, Miaoman Ye, Chi‐Chong Chio, Jinjie Wu, Siyi Fu, Chu‐Xia Deng, Ren‐He Xu   +9 more
wiley   +1 more source

Dynamics of Microbial Communities and Antibiotic Resistance Genes During <i>Arthrospira platensis</i> Cultivation in Swine Wastewater. [PDF]

Biology (Basel)
Promariya A, Treenarat S, Duangsri C, Lansubsakul N, Powtongsook S, Khetkorn W, Raksajit W.   +6 more
europepmc   +1 more source

Structural Basis of Lymphangiogenic Receptor VEGFR‐3 Activation Mediated by Distinctive Clustering of the Ligand–Receptor Complex

Advanced Science, EarlyView.
VEGF‐C and its receptor VEGFR‐3 are critical for lymphangiogenesis. Cryo‐EM structures of the VEGFR‐3/VEGF‐C ectodomain complex reveal a canonical 2:2 ligand–receptor hetero‐tetramer that further assembles into higher‐order clusters beyond simple receptor dimerization.
Ryeongeun Cho, Jinsook Ahn, Jimin Yang, Dong Sun Lee, Gahi Hong, Sangkyu Lee, Ho Min Kim   +6 more
wiley   +1 more source

Review on Antibiotics and Antibiotics Resistance Genes in Environment

Journal of Asian Urban Environment, 2018
Ma, Jun-wen, Cui, Yubo, Zou, Xuejun, Wang, Chao, Feierkate   +4 more
openaire   +1 more source

Airborne Movement of Antibiotic Resistance Genes Between Livestock Stables and Farmers' Homes. [PDF]

Microorganisms
Amin H, Šantl-Temkiv T, Finster K, Schlünssen V, Sigsgaard T, Wouters IM, Sørensen MT, Malinovschi A, Thorarinsdottir H, Bertelsen RJ.   +9 more
europepmc   +1 more source