Results 111 to 120 of about 5,870,697 (401)

Applying the Plan-Do-Study-Act cycle in medical education to refine an antibiotics therapy active learning session [PDF]

, 2021
Stacey Rose, Richard J. Hamill, Andrew Caruso, Nital Appelbaum   +3 more
openalex   +1 more source

Osteomyelitis Complicating Sacral Pressure Ulcers: Whether or Not to Treat With Antibiotic Therapy

Clinical Infectious Diseases, 2018
The treatment of osteomyelitis in patients with stage IV sacral pressure ulcers is controversial. We conducted a systematic literature review and did not find evidence of benefit of antibacterial therapy in this setting without concomitant surgical ...
D. Wong, P. Holtom, B. Spellberg
semanticscholar   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Stenotrophomonas maltophilia as an Emerging Ubiquitous Pathogen: Looking Beyond Contemporary Antibiotic Therapy

Frontiers in Microbiology, 2017
Stenotrophomonas maltophilia is a commensal and an emerging pathogen earlier noted in broad-spectrum life threatening infections among the vulnerable, but more recently as a pathogen in immunocompetent individuals.
A. Adegoke, T. Stenström, A. Okoh
semanticscholar   +1 more source

Evaluating Prescriber Adherence to Guideline-Based Treatment Pathways of a Newly Initiated Antimicrobial Stewardship Program at a Rehabilitation Hospital [PDF]

, 2017
Background: Inappropriate use of antimicrobials in the healthcare setting is associated with consequences including antimicrobial resistance, Clostridium difficile infection (CDI), adverse drug reactions, and increased healthcare costs.
Bertram, Christie
core   +1 more source

Role of the microbiome, probiotics, and 'dysbiosis therapy' in critical illness. [PDF]

, 2016
Purpose of reviewLoss of 'health-promoting' microbes and overgrowth of pathogenic bacteria (dysbiosis) in ICU is believed to contribute to nosocomial infections, sepsis, and organ failure (multiple organ dysfunction syndrome).
Knight, Rob, McDonald, Daniel, Wischmeyer, Paul E   +2 more
core   +2 more sources

Relapsing–Remitting Multiple Sclerosis Is Associated With a Dysbiotic Oral Microbiome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Multiple sclerosis (MS) is a chronic autoimmune disorder characterized by inflammation, demyelination, and neurological impairment. While the gut microbiota's role in MS is extensively studied, the association between the oral microbiota and MS remains underexplored, particularly in North American cohorts.
Sukirth M. Ganesan, Meeta Yadav, Sudeep Ghimire, Peter C. Lehman, Apurva J. Patel, Sydney Woods, Heena Olalde, Jemmie Hoang, Mishelle Paullus, Catherine Cherwin, Christine Gill, Tracey Cho, Ashutosh K. Mangalam   +12 more
wiley   +1 more source

Impact of antibiotic duration in management of diabetic foot osteomyelitis: A systematic review and meta-analysis

CMI Communications
Background: Antibiotics remain a mainstay of therapy for diabetic foot osteomyelitis (DFO), but optimal duration of therapy remains unclear. Objectives: To evaluate the effect of duration of antibiotic therapy on treatment success for DFO.
S Motaganahalli, G Reynolds, S Vogrin, S Haikerwal, T Richards, T Peel, JA Trubiano   +6 more
doaj   +1 more source

Limited effect of patient and disease characteristics on compliance with hospital antimicrobial guidelines [PDF]

, 2005
Objective: Physicians frequently deviate from guidelines that promote prudent use of antimicrobials. We explored to what extent patient and disease characteristics were associated with compliance with guideline recommendations for three common infections.
A Alvarez, DJ McCaig, DT Bearden, EH Ibrahim, EM Brown, European Antimicrobial Resistance Surveillance System, Flora M. Haaijer-Ruskamp, GL Mandell, IC Gyssens, IM Gould, J Avorn, J Cobo, J Gans de, J Hatton, JG Bartlett, John E. Degener, JW Warren, Marian Laseur, ME Kasteren van, ME Kasteren van, Peter G. M. Mol, Petra Denig, PGM Mol, PGM Mol, PGM Mol, PP Cook, Prashant V. NannanPanday, R Grol, Rijk O. B. Gans, RJ Meyer, RP Wenzel, SE Buijk, SJ Atlas, SL Bronzwaer, W Kasje, WA Knaus, WE Stamm   +36 more
core   +3 more sources

Association of Prior Antibiotic Treatment With Survival and Response to Immune Checkpoint Inhibitor Therapy in Patients With Cancer.

JAMA Oncology, 2019
Importance Gut dysbiosis impairs response to immune checkpoint inhibitors (ICIs) and can be caused by broad-spectrum antibiotic (ATB) therapy. Objective To evaluate whether there is an association between ATB therapy administered concurrently (cATB) or
D. Pinato, S. Howlett, D. Ottaviani, Heather Urus, Aisha S Patel, Takashi Mineo, C. Brock, D. Power, O. Hatcher, A. Falconer, M. Ingle, Anna Brown, D. Gujral, S. Partridge, N. Sarwar, Michael Gonzalez, M. Bendle, C. Lewanski, T. Newsom-Davis, E. Allara, M. Bower   +20 more
semanticscholar   +1 more source