Results 101 to 110 of about 3,260,507 (313)

Remote Activation of Wnt Signaling and Cell Proliferation by E‐Cadherin Magnetomechanical Stimulation

open access: yesAdvanced Functional Materials, EarlyView.
A pioneering magnetogenetic toolkit enables non‐invasive, precise spatiotemporal modulation of intracellular Wnt/β‐catenin signaling. Functionalized magnetic nanoparticles (MNPs@E/EC15) target cellular E‐cadherins to generate localized magnetomechanical forces under low‐intensity magnetic fields.
Christian Castro‐Hinojosa   +7 more
wiley   +1 more source

Engineering Antigen Density on M13 Bacteriophage for Personalized Nanovaccine

open access: yesAdvanced Healthcare Materials, EarlyView.
Increasing antigen density on the phage capsid impacts phage uptake and antigen cross‐presentation by antigen‐presenting cells, leading to enhanced activation of antitumor CD8+ T cells in the draining lymph nodes. These activated CD8+ T cells subsequently recognize the antigen‐expressing tumors and mediate their specific cytotoxic killing, thereby ...
Shengnan Huang   +7 more
wiley   +1 more source

Sequence of Antibiotic Administration for the Treatment of Mycobacterium avium subsp. hominissuis Infection Might Influence the Response Outcome

open access: yes
Background/Objectives: Mycobacterium avium subsp. hominissuis is a cause of disseminated infections in immunosuppressed patients and pulmonary infections in individuals with chronic lung conditions.
Stephanie Nuss   +2 more
core   +1 more source

Antibiotic-associated pathogens: the use of animal models to explore disease and alternative therapeutics

open access: yes, 2018
This thesis focused on the study of antibiotic-resistant disease-causing bacteria in the gut, exploring how they cause gut damage, and how they can be displaced without antibiotics.
SARAH ALEXANDRA LARCOMBE (5547650)
core   +1 more source

Hydrogel‐Based Airway‐on‐Tube With Perfusable Endothelial Lumen and Outward Epithelialization

open access: yesAdvanced Materials, EarlyView.
A hydrogel‐based airway‐on‐tube platform featuring a perfusable endothelial lumen and outward epithelialization is presented. The system supports primary human bronchial epithelial and lung microvascular endothelial coculture under air‐liquid interface conditions.
Ali Doryab   +8 more
wiley   +1 more source

Antibiotic therapy failure and clinical outcomes in scrub typhus patients from Guangzhou city, southern China

open access: yesScientific Reports
Antibiotic therapy failure in scrub typhus (ST) has raised concerns about first-line antibiotic efficacy, necessitating reevaluation of recommended antibiotic therapies.
Jiali Long   +5 more
doaj   +1 more source

The Clinical Implications of Inappropriate Therapy in Community-Onset Urinary Tract Infections and the Development of a Bayesian Hierarchical Weighted-Incidence Syndromic Combination Antibiogram

open access: yes
Background/Objectives: The rise in multidrug-resistant pathogens complicates UTI management, particularly in empirical therapy. This study aimed to develop and describe a Bayesian hierarchical weighted-incidence syndromic combination antibiogram (WISCA ...
Pedro Martínez-Ayala   +5 more
core   +1 more source

A Critical Call for Mechanistic Investigations of Metal‐Bacteria Interactions

open access: yesAdvanced Materials, EarlyView.
It is well established that the antibacterial properties of metals have tremendous importance for bioengineering applications. What is not as appreciated, however, is the reproducibility crisis in this field's vast literature. In this perspective, we highlight this reproducibility problem, discuss its sources, and suggest solutions towards focused ...
J. Rackwitz   +9 more
wiley   +1 more source

Optimizing Treatment of Infective Endocarditis in Patients Who Inject Drugs

open access: yesAntibiotics
The treatment of infective endocarditis (IE) in patients who inject drugs (PWID) is complex and challenging. These patients face stigma in the healthcare system, as well as higher mortality, longer length of hospital stay, higher rates of recurrent ...
Jarett Worden   +2 more
doaj   +1 more source

Difficult-to-Treat Pseudomonas aeruginosa Infections in Critically Ill Patients: A Comprehensive Review and Treatment Proposal

open access: yes
The management of infections caused by difficult-to-treat Pseudomonas aeruginosa in critically ill patients poses a significant challenge. Optimal antibiotic therapy is crucial for patient prognosis, yet the numerous resistance mechanisms of P ...
Paula Fernández-Ugidos   +8 more
core   +1 more source

Home - About - Disclaimer - Privacy