Results 131 to 140 of about 188,321 (291)

Enhanced Infection Resistance and Regenerative Healing of Titanium Implants via Peptide‐Loaded Biodegradable Coatings

Advanced Materials Technologies, EarlyView.
This study presents a new biodegradable coating for titanium implants using a natural antimicrobial peptide, caerin 1.9. Applied via solvent casting, the coating offers sustained antibacterial protection and promotes healing. Tested on 3D‐printed porous titanium scaffolds, it effectively prevented infection—including against resistant bacteria—while ...
Hejie Li, Tianfang Wang, Nicolas Soro, Guoying Ni, Meg Allom, D. İpek Kurtböke, Xiaosong Liu, Damon Kent   +7 more
wiley   +1 more source

Antibiotic tolerance leads to antibiotic resistance [PDF]

Nature Medicine, 2020
openaire   +2 more sources

Wet Ball Milling Synthesis of Iron Oxide Nanoparticles for High‐Efficiency, Controllable Magnetic Hyperthermia in Ovarian Cancer

Advanced Materials Technologies, EarlyView.
A wet ball‐milling method is presented to synthesize iron magnetic nanoparticles and evaluate their magnetic hyperthermia performance. Optimized particles (∼270 nm, Ms ∼114 emu/g) achieve ∼50°C heating under clinically safe alternating magnetic fields, while pulsed‐field operation enables controlled temperature regulation (∼30°C).
Shahriar Mostufa, Bahareh Rezaei, Md Shahriar, Karla Mercedes Paz González, Anil Kumar, Changxue Xu, Yun Suk Eo, Ioannis H. Karampelas, Jenifer Gómez‐Pastora, Rui He, Kai Wu   +10 more
wiley   +1 more source

Transcriptomic profiling of ceftriaxone-tolerant phenotypes of Neisseria gonorrhoeae reveals downregulation of ribosomal genes — a pilot study

Microbiology Spectrum
Antibiotic tolerance is associated with failure of antibiotic treatment and accelerates the development of antimicrobial resistance. The molecular mechanisms underlying antimicrobial tolerance remain poorly understood.
Sheeba Santhini Manoharan-Basil, Margaux Balduck, Zina Gestels, Said Abdellati, Tessa De Block, Chris Kenyon   +5 more
doaj   +1 more source

From Lab to Landscape: Environmental Biohybrid Robotics for Ecological Futures

Advanced Robotics Research, EarlyView.
This Perspective explores environmental biohybrid robotics, integrating living tissues, microorganisms, and insects for operation in real‐world ecosystems. It traces the leap from laboratory experiments to forests, wetlands, and urban environments and discusses key challenges, development pathways, and opportunities for ecological monitoring and ...
Miriam Filippi
wiley   +1 more source

Biochemical characteristics of inhaled antibiotics related to tolerability

Farmacia Hospitalaria
Inhaled antibiotics are used in the treatment of various respiratory diseases, including cystic fibrosis (CF), non-CF bronchiectasis, and ventilator-associated pneumonia. While some of these drugs are marketed as ready-to-use formulations, others require prior manipulation, such as dilution or reconstitution procedures that are often not standardized ...
Manuel, Vélez-Díaz-Pallarés, María Ángeles, Parro-Martín, Hilario, Martínez-Barros, Beatriz, Montero-Llorente, Miriam, Menacho-Román, Ana, Gómez-Lozano, Rosa, Nieto Royo, Luis, Máiz Carro, Ana, Álvarez-Díaz   +8 more
openaire   +3 more sources

Interactions of Antibody Drug Conjugate Anti‐Tubulin and Topoisomerase I Inhibitor Payloads with Radiotherapy to Potentiate Immunotherapy

Advanced Science, EarlyView.
Antibody drug conjugates deliver their cytotoxic anti‐tubulin or topoisomerase I inhibitor payloads to tumors through cancer cell receptor targeting. The released drug payloads induce cellular changes that interact with radiotherapy resulting in radiosensitization that improves cancer cell kill and stimulates anti‐tumor immune responses.
Jacqueline Lesperance, Bryan S. Yung, Michael M. Allevato, Marcus M Cheng, Maria F. Camargo, Robert Saddawi‐Konefka, Kanika Dhawan, Ashwyn K. Sharma, Mahsa Mortaja, Sophie Bice, Daniel J. Scanderbeg, Diego Alvarado, Jyoti Mayadev, Ramez N. Eskander, Stephen R. Adams, Pippa F. Cosper, J. Silvio Gutkind, Sunil J. Advani   +17 more
wiley   +1 more source

Graphitic Carbon Nitride Confers Bacterial Tolerance to Antibiotics in Wastewater Relating to ATP Depletion

Molecules
Graphitic carbon nitride (C3N4) is a kind of visible light-responsive photocatalyst that has been of great interest in wastewater treatment. However, its environmental impact and biological effect remains to be elucidated.
Shuo Liu, Lin Teng, Jiantao Ping
doaj   +1 more source

Developing methods for testing the resistance of white cabbage against Thrips tabaci [PDF]

, 2001
Since the damage of the onion thrips (Thrips tabaci Lindemann) first occurred on white cabbage in Hungary several observations have been carried out, both in Hungary and abroad, to assess varietal resistance.
Fail, József, Pénzes, Béla
core  

Piezo2 Mediates a Vicious Cycle of “Mechanical Homeostasis Imbalance—Inflammation” in Sensory Nerves and the Cartilage Endplate

Advanced Science, EarlyView.
In a lumbar spine instability model, dorsal root ganglion cells mediate the perception of relevant mechanical stresses through Piezo2 and subsequently release CGRP. CGRP activates the NF‐κB signaling pathway in cartilage endplate cells through the receptor RAMP1.
Hanpeng Xu, Wen Geng, Zhi Du, Yifan Du, Di Wu, Bide Tong, Huaizhen Liang, Xingyu Zhou, Zixuan Ou, Junyu Wei, Kun Wang, Yu Song, Wenbin Hua, Yan Xu, Wencan Ke, Bingjin Wang, Cao Yang   +16 more
wiley   +1 more source