Results 141 to 150 of about 1,969,887 (183)

Sodium dehydroacetate confers broad antibiotic tolerance by remodeling bacterial metabolism

Journal of Hazardous Materials, 2022
Antibiotic tolerance has been a growing crisis that is seriously threatening global public health. However, little is known about the exogenous factors capable of triggering the development of antibiotic tolerance, particularly in vivo. Here we uncovered
Yuan Liu, Kangni Yang, Ruichao Li
exaly   +2 more sources

Bacterial acid stress response: from cellular changes to antibiotic tolerance and phenotypic heterogeneity.

Current Opinion in Microbiology, 2023
Most bacteria are neutralophiles but can survive fluctuations in pH in their environment. Herein, we provide an overview of the adaptation of several human, soil, and food bacteria to acid stress, mainly based on next-generation sequencing studies ...
Kilian Schumacher, Sophie Brameyer, Kirsten Jung   +2 more
semanticscholar   +1 more source

A dietary source of antibiotic tolerance

Cell Metabolism, 2021
Antibiotic tolerance enables microorganisms to survive the exposure to antibiotics and serves as a precursor to antibiotic resistance. In a recent issue of Nature Microbiology, Liu et al. (2021) describe that high-fat-diet-induced changes in the intestinal microbiome and metabolome facilitate the development of antibiotic tolerance by bacterial ...
Patrick, Lundgren, Prateek V, Sharma, Christoph A, Thaiss   +2 more
openaire   +2 more sources

Serine-threonine phosphoregulation by PknB and Stp contributes to quiescence and antibiotic tolerance in Staphylococcus aureus

Science Signaling, 2023
Staphylococcus aureus can cause infections that are often chronic and difficult to treat, even when the bacteria are not antibiotic resistant because most antibiotics act only on metabolically active cells.
M. Huemer, Srikanth Mairpady Shambat, Sanne Hertegonne, Judith Bergadà-Pijuan, Chun-Chi Chang, S. Pereira, A. Gómez-Mejia, Lies Van Gestel, Julian Bär, Clément Vulin, Sibylle Pfammatter, T. Stinear, I. Monk, J. Dworkin, A. Zinkernagel   +14 more
semanticscholar   +1 more source

Nutrient condition modulates the antibiotic tolerance of Pseudomonas aeruginosa.

Science of the Total Environment, 2023
The variation in nutrient content across diverse environments has a significant impact on the survival and metabolism of microorganisms. In this study, we examined the influence of nutrients on the antibiotic tolerance of the PAO1 strain of Pseudomonas ...
Huizhong Liu, Yingsi Wang, Zhiqing Zhang, Hong Qi, Yu Zhang, Wenru Li, Qingshan Shi, Xiaobao Xie   +7 more
semanticscholar   +1 more source

Non-caloric artificial sweeteners exhibit antimicrobial activity against bacteria and promote bacterial evolution of antibiotic tolerance.

Journal of Hazardous Materials, 2022
Non-caloric artificial sweeteners are being widely used as safe table sugar substitutes with highly intensive sweetness but low calories. Previous studies have suggested that some of the sweeteners can alter the gut microbiota composition and promote ...
Zhigang Yu, J. Guo
semanticscholar   +1 more source

Tolerance to antibiotics affects response

Science, 2020
Bacterial tolerance to antibiotics reduces the ability to prevent ...
Andrew D, Berti, Elizabeth B, Hirsch
openaire   +2 more sources

Tolerance of staphylococci to bactericidal antibiotics

Injury, 2006
Antibiotic therapy for deep-seated staphylococcal infections, especially when they are associated with artificial devices used for orthopedic surgery is often associated with failure. Standard anti-staphylococcal bactericidal antibiotics, such as semi-synthetic penicillins, cephalosporins, or glycopeptides, are effective when given prophylactically in ...
Vaudaux, Pierre, Lew, Daniel Pablo
openaire   +5 more sources

Effects of biochar addition on the fate of ciprofloxacin and its associated antibiotic tolerance in an activated sludge microbiome.

Environmental Pollution, 2022
This study investigated the effects of adding biochar (BC) on the fate of ciprofloxacin (CIP) and its related antibiotic tolerance (AT) in activated sludge.
Seungdae Oh, Youngjun Kim, Donggeon Choi, Ji Won Park, J. Noh, Sang-Yeop Chung, S. Maeng, C. Cha   +7 more
semanticscholar   +1 more source

Antibiotic-induced disease tolerance

Nature Reviews Drug Discovery, 2020
The tetracycline antibiotic doxycycline is shown to not only have direct antimicrobial effects but also promote disease tolerance mechanisms, including tissue repair and metabolic reprogramming.
openaire   +2 more sources