Results 121 to 130 of about 188,321 (291)

Exogenous indole promotes florfenicol tolerance in Edwardsiella tarda

Virulence
Bacterial metabolism is important for antibiotic resistance and tolerance. However, the impact of indole on bacterial metabolism and antibiotic efficacy has not been fully elucidated.
Yu Zheng, Luhua Fu, Zhuoying Cao, Ting Zhang, Jiao Fei, Ming Jiang, Yuying Zhou, Zhi Shi, Yubin Su   +8 more
doaj   +1 more source

Adaptation to high ethanol reveals complex evolutionary pathways [PDF]

, 2015
Tolerance to high levels of ethanol is an ecologically and industrially relevant phenotype of microbes, but the molecular mechanisms underlying this complex trait remain largely unknown.
Arslan, Ahmed, Das, Anupam, De Maeyer, Dries, DeLuna, Alexander, Espinosa-Cantú, Adriana, Jelier, Rob, Kominek, Jacek, Marchal, Kathleen, Meert, Wim, van der Zande, Elisa, Van Noort, Vera, Van Pee, Michiel, Verstrepen, Kevin J, Voordeckers, Karin, Yang, Yudi, Zhu, Bp   +15 more
core   +4 more sources

AI–Guided 4D Printing of Carnivorous Plants–Inspired Microneedles for Accelerated Wound Healing

Advanced Materials, EarlyView.
This work presents an artificial intelligence (AI)‐guided 4D‐printed microneedle platform inspired by carnivorous plants for wound healing. A thermo‐responsive shape memory polymer enables body temperature–triggered self‐coiling for autonomous wound closure.
Hyun Lee, Moon‐Jo Kim, DongEung Kim, Chan Ho Moon, Seojoon Bang, Hyeong Seok Kang, Ju Yeong Gwon, Jong Hwa Seo, Junhyub Jeon, Junhyuk Son, Munwon Lim, Minho Kang, Dong Yun Lee, Donghyun Lim, Jung‐Hoon Park, Gi Doo Cha, Soo‐Hong Lee, Tae‐Sik Jang, Kisuk Yang, Yunho Jeong, Youngho Eom, Hyun‐Do Jung   +21 more
wiley   +1 more source

Conductive Hydrogels for Exogenous Sensing and Cell Fate Control

Advanced Materials, EarlyView.
We engineer electrically conductive hydrogels by combining sulfated glycosaminoglycans with semiconducting polymers. These hydrogels bind bioactive proteins, including growth factors, whose release or retention can be modulated by low‐voltage stimulation. The hydrogels are also integrated as 3D channels in organic electrochemical transistors as part of
Teuku Fawzul Akbar, Carlos Alejandro Jimenez‐Rodriguez, Railia Biktimirova, Ilka Hermes, Thomas Kurth, My Duyen Pham, Mikhail Tsurkan, Jens Friedrichs, Francis L. C. Morgan, Hans Kleemann, Olga Guskova, Uwe Freudenberg, Peter Fratzl, Carsten Werner, Christoph Tondera, Ivan R. Minev   +15 more
wiley   +1 more source

Understanding tolerance to cell wall–active antibiotics

Annals of the New York Academy of Sciences, 2020
AbstractAntibiotic tolerance—the ability of bacteria to survive for an extended time in the presence of bactericidal antibiotics—is an understudied contributor to antibiotic treatment failure. Herein, I review the manifestations, mechanisms, and clinical relevance of tolerance to cell wall–active (CWA) antibiotics, one of the most important groups of ...
openaire   +2 more sources

Itaconate induces tolerance of Staphylococcus aureus to aminoglycoside antibiotics

Frontiers in Microbiology
IntroductionStaphylococcus aureus is one of the chief pathogens that cause chronic and recurrent infections. Failure of the antibiotics to curb the infections contributes to relapse and is an important reason for the high mortality rate.
Runping Zhao, Lei Xu, Jieyun Chen, Jieyun Chen, Jieyun Chen, Jieyun Chen, Jieyun Chen, Yanxian Yang, Yanxian Yang, Yanxian Yang, Yanxian Yang, Yanxian Yang, Xilong Guo, Xilong Guo, Xilong Guo, Xilong Guo, Xilong Guo, Min Dai, Guo-Bao Tian, Guo-Bao Tian, Guo-Bao Tian, Guo-Bao Tian, Guo-Bao Tian, Li-Na Qin, Li-Na Qin   +24 more
doaj   +1 more source

Multisite phosphorylation drives phenotypic variation in (p)ppGpp synthetase-dependent antibiotic tolerance

Nature Communications, 2019
Individual bacteria within isogenic populations can differ in antibiotic tolerance. Here, Libby et al. show that antibiotic tolerance variability can be driven by ‘noisy’ expression of a gene encoding a (p)ppGpp synthetase, which is in turn regulated by ...
Elizabeth A. Libby, Shlomi Reuveni, Jonathan Dworkin   +2 more
doaj   +1 more source

Characterization and Antimicrobial Activity of Hafnium Nanostructures Fabricated by Physical Vapor Deposition Through a Colloidal Mask

Advanced Materials Interfaces, EarlyView.
We generate hafnium nanostructures by first depositing polystyrene particles of varying diameter followed by physical vapour deposition of hafnium thin films. The resultant structure shows a kill‐on‐contact effect against both Gram‐negative Escherichia coli and Gram‐positive Staphylococcus aureus.
Andrew Boden, Tzu‐Ying Liao, Tomas Katkus, Helmut Thissen, De Ming Zhu, Mrinal Bhave, Peter Kingshott   +6 more
wiley   +1 more source

Non-equivalence of antibiotic generic drugs and risk for intensive care patients [PDF]

, 2013
Background: The underlying axiom in applying generic drugs is the equivalence of their active ingredient with the (usually more expensive) innovator product, an all-embracing statement with the insidious result that physicians assume that the generic ...
Barbeck, Mike, Ghanaati, Shahram, Kirkpatrick, Charles James, Rangoonwala, Ramzan, Reshetnykov, Mykhaylo   +4 more
core  

Parallel Electrical Integration of Photo Bio Electrochemical Systems (photo‐BESs): Performance Gains and Load Dependency

Advanced Materials Technologies, EarlyView.
Parallel wiring of bioelectrochemical devices with conventional generators unexpectedly boosts output. A biophotovoltaic paired with a solar cell delivers up to 50% more power at low loads than their separate contributions; a plant microbial fuel cell shows similar current gains.
Valeria Marsaglia, Paolo Bombelli, Ingrid Paoletti, Ioannis A. Ieropoulos, Christopher J. Howe   +4 more
wiley   +1 more source