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Designing antibiotic cycling strategies by determining and understanding local adaptive landscapes [PDF]
, 2013 The evolution of antibiotic resistance among bacteria threatens our continued ability to treat infectious diseases. The need for sustainable strategies to cure bacterial infections has never been greater. So far, all attempts to restore susceptibility after resistance has arisen have been unsuccessful, including restrictions on prescribing [1] and ...
Barlow, Miriam +7 more
arxiv +9 more sources
Antibiotics Time Machine is NP-hard [PDF]
arXiv, 2015 The antibiotics time machine is an optimization question posed by Mira \latin{et al.} on the design of antibiotic treatment plans to minimize antibiotic resistance. The problem is a variation of the Markov decision process. These authors asked if the problem can be solved efficiently. In this paper, we show that this problem is NP-hard in general.
Tran, Ngoc Mai, Yang, Jed
arxiv +3 more sources
Acknowledgment to Reviewers of Antibiotics in 2020
Antibiotics, 2021 Peer review is the driving force of journal development, and reviewers are gatekeepers who ensure that Antibiotics maintains its standards for the high quality of its published papers [...]
Antibiotics Editorial Office
doaj +1 more source
Acknowledgment to Reviewers of Antibiotics in 2021
Antibiotics, 2022 Rigorous peer-reviews are the basis of high-quality academic publishing [...]
Antibiotics Editorial Office
doaj +1 more source
Acknowledgement to Reviewers of Antibiotics in 2019
Antibiotics, 2020 The editorial team greatly appreciates the reviewers who have dedicated their considerable time and expertise to the journal’s rigorous editorial process over the past 12 months, regardless of whether the papers are finally published or not [...]
Antibiotics Editorial Office
doaj +1 more source
Acknowledgment to the Reviewers of Antibiotics in 2022
Antibiotics, 2023 High-quality academic publishing is built on rigorous peer review [...]
Antibiotics Editorial Office
doaj +1 more source
Metabolism and signaling crosstalk in glioblastoma progression and therapy resistance
Molecular Oncology, EarlyView., 2023 Glioblastoma is one of the most lethal human cancers with no effective treatment nowadays. Here, we review the increasing amount of evidence supporting the connection between cell signaling deregulation and metabolic reprogramming as a key event in glioblastoma resistance to cancer therapy.
Laura Zarzuela +2 more
wiley +1 more source
Antibiotic Potential of Marine Actinomycetes of the Genera Streptomyces and Nocardiopsis
Антибиотики и Химиотерапия, 2023 Due to the emergence of antibiotic resistance in pathogenic microorganisms, it is urgent to search for producers of new antimicrobial metabolites. Actinomycetes are gram-positive mycelial bacteria that produce a large number of antibiotics used in ...
O. N. Sineva +5 more
doaj +1 more source
Antibiotics, 2020 The authors have been made aware that two figures were published in two papers: Figure 5A in paper [...]
Antibiotics Editorial Office
doaj +1 more source
Incentivizing Narrow-Spectrum Antibiotic Development with Refunding [PDF]
Bull Math Biol 84, 59 (2022), 2020 The rapid rise of antibiotic resistance is a serious threat to global public health. Without further incentives, pharmaceutical companies have little interest in developing antibiotics, since the success probability is low and development costs are huge.
arxiv +1 more source