Results 101 to 110 of about 868,436 (327)

Antibiotic resistant characteristics from 16S rRNA [PDF]

arXiv, 2012
Background: Microbiota have evolved to acclimate themselves to many environments. Humanity is become ever increasingly medicated and many of those medications are antibiotics. Sadly, Microbiota are adapting to medication and with each passing generation they become more difficult to subdue.
arxiv  

IncRNA‐ZFAS1, an Emerging Gate‐Keeper in DNA Damage‐Dependent Transcriptional Regulation

Advanced Science, EarlyView.
LncZFAS1 plays a crucial role during DNA damage response in mammalian cells. Loss of lncZFAS1 results in deficient DNA lesion removal and reduced cell viability. Mechanistically, lncZFAS1 modulates RNAPII phosphorylation and transcription and thereby promotes both GG‐NER and TC‐NER upon UV damage.
Jiena Liu, Qing Lu, Zixuan Fan, Jiahui Lin, Nan He, Xin Zhang, Zhaoya Han, Tingting Zhu, Zhenzhen Wu, Yingying Xu, Yuming Wang   +10 more
wiley   +1 more source

Medication-Induced Oral Hyperpigmentation: A Systematic Review

Patient Preference and Adherence, 2020
Nada O Binmadi, Maram Bawazir, Nada Alhindi, Hani Mawardi, Ghada Mansour, Sana Alhamed, Sarah Alfarabi, Sara Akeel, Soulafa Almazrooa Oral Diagnostic Sciences Department, Faculty of Dentistry, King Abdulaziz University, Jeddah, Saudi ArabiaCorrespondence:
Binmadi NO, Bawazir M, Alhindi N, Mawardi H, Mansour G, Alhamed S, Alfarabi S, Akeel S, Almazrooa S   +8 more
doaj  

Antibiotics Time Machine is NP-hard [PDF]

arXiv, 2015
The antibiotics time machine is an optimization question posed by Mira \latin{et al.} on the design of antibiotic treatment plans to minimize antibiotic resistance. The problem is a variation of the Markov decision process. These authors asked if the problem can be solved efficiently. In this paper, we show that this problem is NP-hard in general.
arxiv  

Pharmaceuticals, except biologicals : 2009 [PDF]

, 2010
Current industrial report.

core  

Evaluation of combination therapy for Burkholderia cenocepacia lung infection in different in vitro and in vivo models [PDF]

, 2017
Burkholderia cenocepacia is an opportunistic pathogen responsible for life-threatening infections in cystic fibrosis patients. B. cenocepacia is extremely resistant towards antibiotics and therapy is complicated by its ability to form biofilms.
Brackman, Gilles, Cappoen, Davie, Coenye, Tom, Cos, Paul, Crabbé, Aurélie, Rigole, Petra, Van den Driessche, Freija, Vanhoutte, Bieke, Vercruysse, Jurgen, Verstraete, Glenn, Vervaet, Chris   +10 more
core   +4 more sources

Ultrasound‐Responsive 4D Bioscaffold for Synergistic Sonopiezoelectric‐Gaseous Osteosarcoma Therapy and Enhanced Bone Regeneration

Advanced Science, EarlyView.
An acoustic‐responsive therapeutic platform for synergistic sonopiezoelectric‐gaseous osteosarcoma therapy and bone regeneration is fabricated through the joint loading of few‐layer black phosphorus nanosheets and S‐Nitroso‐L‐glutathione onto the 3D‐printed bioactive glass scaffolds.
Haoyu Fang, Daoyu Zhu, Yixuan Chen, Changqing Zhang, Gan Li, Qihang Fang, Meiqi Chang, Yu Chen, Youshui Gao   +8 more
wiley   +1 more source

A Prospective Analysis of Adverse Drug Reactions in a South Indian Hospital [PDF]

, 2009
Adverse drug reactions are a great cause of concern to the medical profession, the patients and the pharmaceutical industry. However ADR reporting and monitoring is yet to catch up in India.
Adhikari, P, Padmaja, U, Pereira, P
core  

Enhanced Catalytic Cycle of Glucose Oxidation and Reactive Species with ROS and RHS Generation Mediated by Galvanic Engineering of Dual Atomic Sites on Covalent Organic Frameworks Demonstrating Synergistic Bimetal Tumor Treatment

Advanced Science, EarlyView.
A galvanic replacement is used to control dual atomic metals (Au and Ir) on a covalent organic framework (COF) nanoparticle and then coated with hyaluronic acid (HA). Under a specific bimetallic ratio (COF/Aux/Ir1‐x), the optimization can be achieved for the conversion of intracellular nutrients into reactive species (HOCl and O2• ─) and effectively ...
Wei‐Chung Pan, Cheng‐Hung Luo, Wen‐Ling Lin, Liu‐Chun Wang, Divinah Manoharan, Po‐Ya Chang, Hwo‐Shuenn Sheu, Chen‐Hao Yeh, Chia‐Jui Yen, Chen‐Sheng Yeh   +9 more
wiley   +1 more source

Single‐Cell Analysis Reveals that Vitamin C Inhibits Bone Metastasis of Renal Cancer via Cell Cycle Arrest and Microenvironment Remodeling

Advanced Science, EarlyView.
3D‐cultured renal cancer cells exhibit stem‐like phenotypes and are more efficient in generating bone metastases. Vitamin C treatment can suppress the development of bone metastasis. Single‐cell transcriptomic analysis reveals that vitamin C inhibits metastasis by inducing tumor cell cycle arrest, suppressing osteoclast differentiation, and reducing ...
Jianye Zhang, Qi Zhang, Gang Lin, Ying Wang, Juan Li, Ping Wang, Jie Qi, Yuan Liang, Shiming He, Yanqing Gong, Ninghan Feng, Yang Wang, Yuanyuan Ma, Mei Zhang, Yue Shi, Xuesong Li, Weimin Ci, Liqun Zhou   +17 more
wiley   +1 more source