Results 101 to 110 of about 855,762 (278)
MAGEA6 Engages a YY1‐Dependent Transcription to Dictate Perineural Invasion in Colorectal Cancer
Advanced Science, EarlyView.This study investigates the role of MAGEA6 in perineural invasion (PNI) in colorectal cancer (CRC). MAGEA6 promotes CRC invasiveness by inhibiting YY1 ubiquitination, enhancing CXCL1 secretion, and recruiting Schwann cells. These findings highlight the potential of targeting the MAGEA6/YY1/CXCL1 axis for therapeutic strategies against PNI and tumor ...
Hao Wang +9 more
wiley +1 more source
Battling Antibiotic Resistance: Can Machine Learning Improve Prescribing? [PDF]
arXiv, 2019 Antibiotic resistance constitutes a major health threat. Predicting bacterial causes of infections is key to reducing antibiotic misuse, a leading driver of antibiotic resistance. We train a machine learning algorithm on administrative and microbiological laboratory data from Denmark to predict diagnostic test outcomes for urinary tract infections ...
arxiv
Lignin‐Based Photothermal Materials: Bridging Sustainability and High‐Efficiency Energy Conversion
Advanced Science, EarlyView.This review provides new perspectives on lignin‐based photothermal materials, emphasizing their molecular structure for efficient energy conversion. It summarizes mechanisms and strategies for improving photothermal efficiency in applications of photothermal actuation, desalination, and biomedical therapies.
Zhiwen Sun +10 more
wiley +1 more source
ChemBioChem, Volume 23, Issue 23, December 5, 2022., 2022 Housing sulfur: Certain fungi produce diketopiperazine compounds with a transannular sulfur bridge. These so‐called epipolythiodioxopiperzines are toxic by non‐specifically interacting with intracellular proteins and contribute to fungal pathogenicity. Producer strains serve as bio‐pesticides but also question safety of food fermentation.
Eva M. Huber
wiley +1 more source
BMC Health Services Research, 2019 Background Medication safety in cancer patients receiving complex medication regimens is an important problem in various settings. Medication related events, interceptions and interventions are not well described in this area.
Marium Azim +3 more
doaj +1 more source
Biomedical Applications of Gadolinium‐Containing Biomaterials: Not Only MRI Contrast Agent
Advanced Science, EarlyView.This paper summarizes the latest applications and potential mechanisms of the rare earth element gadolinium in biomedical fields, in addition to its traditional application as an MRI contrast agent, including osteogenesis, antimicrobial, antitumor, bioimaging, bioprobes, and so on.
Xingtong Pan +9 more
wiley +1 more source
ChemBioChem, Volume 23, Issue 23, December 5, 2022., 2022 Fifteen new dinuclear arene‐ruthenium (II)‐BODIPY conjugates were synthesized. Despite a fluorescence quenching effect, these conjugates can be used as fluorescent tracers. Their antiparasitic activity but also their toxicity against healthy human foreskin fibroblasts (HFFs) was reduced compared to the parent ruthenium compounds.
Oksana Desiatkina +6 more
wiley +1 more source
Growth-dependent bacterial susceptibility to ribosome-targeting antibiotics [PDF]
Molecular Systems Biology 11:796 (2015), 2014 Bacterial growth environment strongly influences the efficacy of antibiotic treatment, with slow growth often being associated with decreased susceptibility. Yet in many cases the connection between antibiotic susceptibility and pathogen physiology remains unclear.
arxiv
Advanced Science, EarlyView.This study develops a strategy to screen the active compounds from bio‐mixtures via combining transcriptomic profiling and molecular docking. The proposed method demonstrates 100% correction in three different biobased mixtures and is 3–20 times faster than traditional approaches.
Yongdong Xu +8 more
wiley +1 more source
Revista Latino-Americana de Enfermagem, 2006 Hospital nursing workers are exposed to occupational chemical risks. This quantitative study aimed to identify what chemical substances nurses have contact with in their activities, what substances cause health problems and what alterations correspond to
Rosicler Xelegati +3 more
doaj +1 more source