Results 121 to 130 of about 855,762 (278)

Turning on the Heat by Cocrystal Engineering: The Rise of Organic Charge Transfer Photothermal Cocrystals as an Emerging Therapeutic Frontier in Biomedical Application

Aggregate, EarlyView.
This review summarizes recent developments in the design of photothermal charge transfer cocrystals for antibacterial therapy, cancer eradication, and bone regeneration, highlighting the design motivations and chemical principles of the strategies. It offers deep insights into the future development of advanced photothermal cocrystals for targeted ...
Arshad Khan, Rabia Usman, Shuo Xiang, Yasinalli Tamboli, Muhammad Umair, Awatef M. Alshehri, Ibraheem Bushnak, Yan Deng, Nongyue He   +8 more
wiley   +1 more source

When to wake up? The optimal waking-up strategies for starvation-induced persistence [PDF]

arXiv, 2019
Prolonged lag time can be induced by starvation contributing to the antibiotic tolerance of bacteria. We analyze the optimal lag time to survive and grow the iterative and stochastic application of antibiotics. A simple model shows that the optimal lag time exhibits a discontinuous transition when the severeness of the antibiotic is increased.
arxiv  

Multi‐Module Micro/Nanorobots for Biomedical and Environmental Remediation Applications

Advanced Intelligent Systems, EarlyView.
Multi‐module microrobots (MNRs) have overcome the limitations of single‐module systems by integrating components such as propeller, actuator, manipulator, and imaging modalities. They show promise in biomedical applications, such as targeted drug delivery and tissue repair, as well as in environmental remediation, including pollutant removal.
Bairong Zhu, Amar Salehi, Lei Xu, Wei Yuan, Tingting Yu   +4 more
wiley   +1 more source

Enaminone‐Based Push–Pull Chromophores: Synthesis, Optical Properties, and Computational Insights

Asian Journal of Organic Chemistry, EarlyView.
Enaminones, known for their pharmacophoric properties, were combined with alkyne units to create complex chromophore structures through click‐type [2 + 2] cycloaddition‐retroelectrocyclization reactions. The ICT characteristics of the synthesized compounds were analyzed using both experimental and computational approaches.
Mehmet Mart, Isıl Irmak Kuyucu, Cagatay Dengiz   +2 more
wiley   +1 more source

Effects of Structural Variations on Antibacterial Properties for Conjugated Diynes Generated through Glaser Hay Couplings

ChemMedChem, Volume 17, Issue 24, December 16, 2022., 2022
A series of conjugated diynes were prepared via both solution phase and solid‐supported Glaser Hay couplings and screened for selective antibacterial activities. A focused structure–activity relationship screen was performed to identify key components of natural product derivatives that were essential for biological activity.
Emma A. Hale, Hannah M. Ryan, Alexandra M. McOsker, Cody M. Funk, Lauren C. Green, Lauren E. Mazur, Diya M. Uthappa, Brian M. Flood, Douglas D. Young, Robert J. Hinkle   +9 more
wiley   +1 more source

Identification of bioactive compounds and molecular targets of Fuke Huahuang formulation to treat vaginitis

Animal Models and Experimental Medicine, EarlyView.
Fuke Huahuang formulation (FHF) is used to treat vaginitis, and it exerts a promising anti‐inflammatory effect in clinical use. However, the detailed components and mechanisms of FHF for treating vaginitis remain unreported, and further preclinical evaluation is required to reveal its potential pharmacological activities against vaginitis.
Huiyu Liu, Jie Mo, Cheng Liang, Qingting Chen, Bin Yang, Jiaqi Liu   +5 more
wiley   +1 more source

Architected Microalgae‐Based Matter via 3D Printing: Properties, Printing Techniques, and Applications

Advanced NanoBiomed Research, EarlyView.
Microalgae are emerging as sustainable and economical bioresources that can be utilized as bioinks for creating constructs with intriguing functionalities. This review discusses the properties and applications of microalgae, providing a comprehensive review of recent advancements and challenges in 3D‐printed microalgae‐based constructs for various ...
Yiwei Zou, Jiuhong Yi, Yunlu Dai, Iek Man Lei   +3 more
wiley   +1 more source

Diamond Chemistry: Advances and Perspectives

Angewandte Chemie International Edition, Accepted Article.
Diamond as a material has many unique properties. More recently, diamond has emerged as a material with a wide range of applications in chemistry and biology. The high intrinsic stability of diamond, coupled with the ability to modify diamond surfaces with a wide range of species via highly stable covalent linkages, provides a wealth of opportunity to ...
Nianjun Yang, Anke Krueger, Robert J. Hamers   +2 more
wiley   +1 more source

When a Safety Signal Appears: Do the Right Thing

Frontiers in Public Health, 2013
John Franklyn Riefler
doaj   +1 more source

Enhancing Antibiotic Stewardship using a Natural Language Approach for Better Feature Representation [PDF]

arXiv
The rapid emergence of antibiotic-resistant bacteria is recognized as a global healthcare crisis, undermining the efficacy of life-saving antibiotics. This crisis is driven by the improper and overuse of antibiotics, which escalates bacterial resistance. In response, this study explores the use of clinical decision support systems, enhanced through the
arxiv