Results 121 to 130 of about 1,248,661 (298)
Are antibiotics naturally antibiotics?
Journal of Industrial Microbiology & Biotechnology, 2006 Antibiotics have been used for more than 50 years and are the cornerstone of infectious disease treatment; in addition, these low-molecular-weight bioactive compounds have been applied to many other therapeutic purposes. However, there is almost no information on the evolutionary biology or ecology of naturally occurring low-molecular-weight compounds.
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FEBS Open Bio, EarlyView.We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen +5 more
wiley +1 more source
Which antibiotics should I use?
, 2015 “Which antibiotic should I use?” It’s a question we ask ourselves when we want to initiate antibiotic treatment for our patients. When patients approach us at the clinic or hospital with fever or other symptoms of infection, they hope that they will be ...
Shalihin, Mohd Shaiful Ehsan
core
FEBS Open Bio, EarlyView.The brown marmorated stink bug, Halyomorpha halys, mainly secretes 4‐oxo‐(E)‐2‐hexenal, (E)‐2‐decenal, dodecane and tridecane, a mixture representative of that released by many heteropterans. We demonstrated that H. halys can synthesise these secretory components de novo using dietary glucose.
Haruna Fujimori, Koji Noge
wiley +1 more source
Background: Prescribing of strong opioids and antibiotics impacts patient safety, yet little is known about the effects GP wellness has on overprescribing of both medications in primary care.Aim: To examine associations between strong opioid and ...
Chew-Graham, Carolyn A +12 more
core +1 more source
Screening of Antibacterial and Antifungal Activities of Basidiomycetes Extracts
Антибиотики и ХимиотерапияBackground. Basidiomycetes have high biosynthetic capabilities. Their metabolites are capable of exhibiting antimicrobial properties, thereby being promising molecules for use in medicine or for further chemical transformation.
V. S. Lysakova +3 more
doaj +1 more source
Antibiotics and Antibiotic Resistance
Biomedical Journal of Scientific & Technical Research, 2017 According to the World Health Organization (WHO)’s "First Global Report on Antibiotic Resistance“, and the U.S. Centers for Disease Control & Prevention (CDC&P), the spread of "superbugs“ - bacteria that have changed in ways that render antibiotics ineffective against them - is a serious and growing threat around the world...
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GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
FEBS Open Bio, EarlyView.GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
Антибиотики и Химиотерапия, 2020 To establish the relationships between the enrichment of resistant Staphylococcus aureus mutants and the ratio of daily area under the concentration - time curve (AUC24) to the MIC of linezolid, a mixed inoculum of linezolid-susceptible and -resistant ...
K. N. Alieva +4 more
doaj
FEBS Open Bio, EarlyView.The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez +4 more
wiley +1 more source