Results 11 to 20 of about 796,820 (50)

Antibiotics in the environment: causes and consequences

Medicine and Pharmacy Reports, 2020
Antibiotics represent one of the main discoveries of the last century that changed the treatment of a large array of infections in a significant way. However, increased consumption has led to an exposure of bacterial communities and ecosystems to a large
Svetlana Iuliana Polianciuc, A. Gurzău, B. Kiss, Maria-Georgia Ștefan, F. Loghin   +4 more
semanticscholar   +1 more source

A Randomized Trial Comparing Antibiotics with Appendectomy for Appendicitis.

New England Journal of Medicine, 2020
BACKGROUND Antibiotic therapy has been proposed as an alternative to surgery for the treatment of appendicitis. METHODS We conducted a pragmatic, nonblinded, noninferiority, randomized trial comparing antibiotic therapy (10-day course) with ...
Coda Collaborative, D. Flum, G. Davidson, Sarah E. Monsell, N. Shapiro, S. Odom, Sabrina E. Sanchez, F. T. Drake, Katherine N. Fischkoff, Jeffrey Johnson, J. Patton, H. Evans, J. Cuschieri, A. Sabbatini, B. Faine, D. Skeete, M. Liang, Vance Y. Sohn, Karen McGrane, M. Kutcher, B. Chung, D. Carter, P. Ayoung-Chee, W. Chiang, A. Rushing, S. Steinberg, Careen S Foster, Shaina Schaetzel, T. Price, K. Mandell, L. Ferrigno, M. Salzberg, D. DeUgarte, A. Kaji, G. Moran, D. Saltzman, H. Alam, P. Park, L. Kao, Callie M. Thompson, W. Self, Julianna T Yu, A. Wiebusch, R. Winchell, S. Clark, A. Krishnadasan, Erin Fannon, D. Lavallee, B. Comstock, B. Bizzell, P. Heagerty, L. Kessler, D. Talan   +52 more
semanticscholar   +1 more source

Pollution by Antibiotics and Antimicrobial Resistance in LiveStock and Poultry Manure in China, and Countermeasures

Antibiotics, 2021
The demand for animal protein has increased considerably worldwide, especially in China, where large numbers of livestock and poultry are produced. Antibiotics have been widely applied to promote growth and prevent diseases.
M. Tian, Xinmiao He, Yanzhong Feng, Wen-tao Wang, Heshu Chen, Ming Gong, Di Liu, J. Clarke, André van Eerde   +8 more
semanticscholar   +1 more source

Antibiotics versus biofilm: an emerging battleground in microbial communities

Antimicrobial Resistance and Infection Control, 2019
Biofilm is a complex structure of microbiome having different bacterial colonies or single type of cells in a group; adhere to the surface. These cells are embedded in extracellular polymeric substances, a matrix which is generally composed of eDNA ...
D. Sharma, Lama Misba, Asad U. Khan
semanticscholar   +1 more source

Actinomycetes: A Never-Ending Source of Bioactive Compounds—An Overview on Antibiotics Production

Antibiotics, 2021
The discovery of penicillin by Sir Alexander Fleming in 1928 provided us with access to a new class of compounds useful at fighting bacterial infections: antibiotics.
Davide De Simeis, S. Serra
semanticscholar   +1 more source

Antibiotics in the Soil Environment—Degradation and Their Impact on Microbial Activity and Diversity

Frontiers in Microbiology, 2019
Antibiotics play a key role in the management of infectious diseases in humans, animals, livestock, and aquacultures all over the world. The release of increasing amount of antibiotics into waters and soils creates a potential threat to all ...
M. Cycoń, A. Mrozik, Z. Piotrowska-Seget   +2 more
semanticscholar   +1 more source

Insights into the Fate and Removal of Antibiotics in Engineered Biological Treatment Systems: A Critical Review.

Environmental Science and Technology, 2019
Antibiotics, the most frequently prescribed drugs of modern medicine, are extensively used for both human and veterinary applications. Antibiotics from different wastewater sources (e.g., municipal, hospitals, animal production, and pharmaceutical ...
A. Oberoi, Yanyan Jia, Huiqun Zhang, S. Khanal, Hui Lu   +4 more
semanticscholar   +1 more source

Antibiotics: Conventional Therapy and Natural Compounds with Antibacterial Activity—A Pharmaco-Toxicological Screening

Antibiotics, 2021
Antibiotics are considered as a cornerstone of modern medicine and their discovery offers the resolution to the infectious diseases problem. However, the excessive use of antibiotics worldwide has generated a critical public health issue and the ...
Daniel Florin Pancu, A. Scurtu, Ioana Macașoi, D. Marti, Marius Mioc, Codruţa Şoica, D. Coricovac, D. Horhat, M. Poenaru, C. Dehelean   +9 more
semanticscholar   +1 more source

Oral versus Intravenous Antibiotics for Bone and Joint Infection

New England Journal of Medicine, 2019
BACKGROUND The management of complex orthopedic infections usually includes a prolonged course of intravenous antibiotic agents. We investigated whether oral antibiotic therapy is noninferior to intravenous antibiotic therapy for this indication. METHODS
Ho‐Kwong Li, I. Rombach, R. Zambellas, S. Walker, M. McNally, B. Atkins, Benjamin A Lipsky, H. Hughes, D. Bose, Michelle Kümin, C. Scarborough, P. Matthews, A. Brent, J. Lomas, R. Gundle, M. Rogers, Adrian Taylor, B. Angus, I. Byren, A. Berendt, S. Warren, F. Fitzgerald, D. Mack, S. Hopkins, J. Folb, H. Reynolds, E. Moore, J. Marshall, N. Jenkins, C.E. Moran, A. Woodhouse, S. Stafford, A. Seaton, C. Vallance, C. Hemsley, K. Bisnauthsing, J. Sandoe, I. Aggarwal, S. Ellis, Deborah J. Bunn, R. Sutherland, G. Barlow, C. Cooper, C. Geue, N. McMeekin, A. Briggs, P. Sendi, E. Khatamzas, T. Wangrangsimakul, N. Wong, L. Barrett, A. Alvand, Fraser Old, J. Bostock, J. Paul, G. Cooke, G. Thwaites, P. Bejon, M. Scarborough   +58 more
semanticscholar   +1 more source

Quinolone antibiotics

MedChemComm, 2019
The quinolone antibiotics arose in the early 1960s, with the first examples possessing a narrow-spectrum activity with unfavorable pharmacokinetic properties.
Thu D M Pham, Z. Ziora, M. Blaskovich
semanticscholar   +1 more source