Results 31 to 40 of about 17,237 (205)

Systemic Lupus Erythematosus With Catastrophic APS and Libman-Sacks Endocarditis in a Patient With Autoimmune Hemolytic Anemia: A Case Report. [PDF]

Clin Case Rep
ABSTRACT Systemic lupus erythematosus (SLE) can lead to antiphospholipid syndrome (APS) and catastrophic APS (CAPS), causing severe thrombotic events. This case of autoimmune hemolytic anemia (AIHA) with stroke and Libman–Sacks endocarditis highlights the need for APS evaluation and shows that prompt anticoagulation and immunosuppressive therapy are ...
Ehsan S, Afshar S, Bakhtiari S, Pourfallah R, Danaei Mehrabad S.   +4 more
europepmc   +2 more sources

Simultaneous Quantification of Anticardiolipin IgG and IgM by Time Resolved Fluoroimmunoassay. [PDF]

PLoS ONE, 2016
The autoimmune disease antiphospholipid syndrome (APS) is characterized by the presence of anticardiolipin antibodies (aCL), along with anti-β2-glycoprotein I (β2GPI) antibodies and lupus anticoagulant (LA).
Zhigang Hu, Xiaoying Jing, Jie Liu, Mei Li, Yan Ye, Yu Chen   +5 more
doaj   +1 more source

Case report: MELAS and concomitant presumed antiphospholipid antibody syndrome in an adult woman

Frontiers in Neurology, 2022
Mitochondrial encephalomyopathy, lactic acidosis, stroke-like episodes, and other features (short stature, headaches, seizures, and sensorineural hearing loss) constitute characteristics of MELAS syndrome.
Sirisha Nouduri, Rajiv Padmanabhan, Richard Hicks, Mary-Alice Abbott, Dennis O'Brien, Gottfried Schlaug   +5 more
doaj   +1 more source

Catastrophic secondary antiphospholipid syndrome with peripheral nervous system involvement: a case report. [PDF]

, 2004
A 34-year-old woman was admitted to our emergency room with a high fever, abdominal pain, dyspnea and confusion. High fever and abdominal pain had first occured after a cystocele operation 5 months earlier.
Erten, Nilgun, Karan, M Akif, Parman, Yesin, Saka, Bulent, Tascioglu, Cemil, Umman, Berrin   +5 more
core   +1 more source

Comparative study between primary and secondary antiphospholipid syndrome: clinic and laboratorial characteristics of 149 patients [PDF]

, 2008
OBJETIVOS: O presente estudo tem como objetivo analisar as características clínicas, laboratoriais e imunológicas dos pacientes com síndrome antifosfolípide (SAF) e comparar indivíduos portadores da síndrome primária com portadores da secundária ...
CARVALHO, Jozélio Freire de, GRANDO, Paulo Eduardo Daruge, QUAIO, Caio Robledo D'Angioli Costa   +2 more
core   +2 more sources

Prognostic Value of Lupus Anticoagulant and Anti–β2 Glycoprotein I Antibody in Adverse Pregnancy Outcomes

Arthritis &Rheumatology, EarlyView.
Objective International criteria for antiphospholipid syndrome (APS) include lupus anticoagulant (LA), anticardiolipin (aCL) IgG and IgM, and anti–β2‐glycoprotein I (β2GPI) IgG and IgM. However, evidence supporting their prognostic value or treatment efficacy in improving live birth rates is limited.
Megumi Nonobe, Takahiro Otani, Hiroyuki Yoshihara, Shinobu Goto, Tamao Kitaori, Naomi Nishikawa, Yuichiro Fujieda, Tatsuya Atsumi, Mayumi Sugiura‐Ogasawara   +8 more
wiley   +1 more source

Cognitive functions and autoantibodies in patients with systemic lupus erythematosus

Psychiatria i Psychologia Kliniczna, 2016
Introduction: Autoantibodies may occur in the course of various diseases. In the case of systemic lupus erythematosus the presence of specific autoantibodies is included in the classification criteria of the disease.
Anna Bogaczewicz, Jakub Ząbek, Tomasz Sobów, Ewa Robak, Jarosław Bogaczewicz, Anna Woźniacka   +5 more
doaj   +1 more source

Prothrombotic Activation of Platelet Pannexin 1 Channels in Antiphospholipid Syndrome

Arthritis &Rheumatology, Accepted Article.
Background ATP is released from platelets through both degranulation and pannexin‐1 (PANX1) channels. ATP then activates P2X receptors to amplify platelet activation via calcium‐dependent signaling. Objective To evaluate the role of platelet PANX1 channels in the pathophysiology of antiphospholipid syndrome (APS), an acquired thrombo‐inflammatory ...
Bruna de Moraes Mazetto Fonseca, Somanathapura K. NaveenKumar, Srilakshmi Yalavarthi, Kavya Sugur, Thalia G. Newman, Claire K. Hoy, Cyrus Sarosh, Jordan K. Schaefer, Ajay Tambralli, Jacqueline A. Madison, Yu Zuo, Fernanda Orsi, Michael Holinstat, Jason S. Knight   +13 more
wiley   +1 more source

Determination and Correlation of Anticardiolipin Antibody with High Sensitivity C- reactive Proteins and its Role in Predicting Short Term Outcome in Patients with Acute Coronary Syndrome [PDF]

, 2011
Anticardiolipin antibody (aCL) is considered to be an independent risk factor while high sensitivity C reactive protein (hsCRP) is an established marker for coronary artery disease. This study was conducted to determine levels of aCL antibodies and hsCRP,
Gupta, V, Kapoor, N, Kashyap, JR, Malhotra, AS, Mehta, J, Sachdev, A, Sharma, R   +6 more
core  

Molecular stratification of antiphospholipid syndrome through integrative analysis of the whole‐blood RNA transcriptome

Arthritis &Rheumatology, Accepted Article.
Objective Antiphospholipid syndrome (APS) is a thrombo‐inflammatory disorder characterized by clinical and mechanistic heterogeneity that complicates early diagnosis and hinders targeted treatment. We aimed to identify distinct molecular endotypes among antiphospholipid antibody (aPL)‐positive patients using whole‐blood transcriptomics.
Amala Ambati, Feiyang Ma, Katarina Kmetova, Sherwin Navaz, Claire K. Hoy, Cyrus Sarosh, Ajay Tambralli, Erika Navarro‐Mendoza, Johann E. Gudjonsson, J. Michelle Kahlenberg, Jacqueline A. Madison, Alí Duarte‐García, Jason S. Knight, Yu Zuo   +13 more
wiley   +1 more source