Results 191 to 200 of about 513,078 (230)
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Antiphospholipid Antibodies and Reproduction
American Journal of Reproductive Immunology, 1989ABSTRACT: Antiphospholipid antibodies (APAs) may be identified in the laboratory by using either coagulation studies or solid‐phase immunologic assays (ELISA; RIA). These methodologies do not necessarily evaluate the same antibody; consequently, it is appropriate to screen a patient's plasma by utilizing both assays.
D A, Triplett, E N, Harris
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Antiphospholipid antibodies and atherosclerosis
Lupus, 1998β2-Glycoprotein I (β2-GPI) is a major antigen for anticardiolipin antibodies (aCL) induced in patients with antiphospholipid syndrome and their antigenic epitopes are cryptic. The epitopes appear on the surface of β2-GPI molecule only when β2-GPI interacts with lipid membranes containing negatively charged phospholipids or polyoxygenated polystyrene ...
E, Matsuura +3 more
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Antiphospholipid antibodies and pregnancy
Best Practice & Research Clinical Haematology, 2003Antiphospholipid antibodies, i.e. lupus anticoagulants and anticardiolipin antibodies, are associated with obstetric complications. Fetal death and recurrent spontaneous abortions represent the obstetric criteria of the antiphospholipid syndrome. They occur with similar frequences and have an overall prevalence of 15-20%.
Monica, Galli, Tiziano, Barbui
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ANTIPHOSPHOLIPID ANTIBODY SYNDROME
Rheumatic Disease Clinics of North America, 1992The antiphospholipid syndrome is now well recognized and is separable from SLE, but better quantitation of both the clinical elements and the serologic definitions is still needed. It is likely for autoimmune but not for infection-induced aPL that the antigen is not phospholipid itself but a complex formed by phospholipid and beta 2 glycoprotein I ...
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Antiphospholipid antibodies and infertility
Human Fertility, 2002Antiphospholipid antibodies (aPL) are an established cause of recurrent pregnancy loss. As defective embryonic implantation is a common link between unexplained infertility and recurrent miscarriage, interest has focused on the potential relationship between aPL and implantation failure after in vitro fertilization and embryo transfer (IVF-ET).
May, Backos, Raj, Rai, Lesley, Regan
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Antiphospholipid antibodies and the endothelium
Current Rheumatology Reports, 2000This article reviews current understanding of the relationship between antiphospholipid antibodies and the endothelium. In vitro antiphospholipid antibodies produce endothelial cell activation. Clinical data in this area are scanty and worthy of future research, which could lead to new therapies in the management of antiphospholipid syndrome.
B J, Hunt, M A, Khamashta
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Antiphospholipid antibody syndrome
Current Treatment Options in Cardiovascular Medicine, 2003Antiphospholipid antibody syndrome (APS) is a recently defined autoimmune disorder characterized by recurrent vascular thromboses or recurrent pregnancy morbidity; these features are linked to the presence in blood of autoantibodies against negatively charged phospholipids or phospholipid-binding proteins.
Elena, Cucurull +3 more
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Antiphospholipid antibodies and reproduction
Journal of Reproductive Immunology, 1997The antiphospholipid antibodies (APA) are acquired antibodies against a phospholipid which has been associated with slow progressive thrombosis and infarction in the placenta. Clinical features (venous or arterial thrombosis, recurrent fetal loss, thrombocytopenia) in conjunction with positive laboratory findings (positive IgG or IgM anticardiolipin ...
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Antiphospholipid Antibodies in Migraine
Headache: The Journal of Head and Face Pain, 1991SYNOPSIS We studied the presence of serum antiphospholipid antibodies (APA) in 35 patients with migraine and 75 controls. None of the controls showed APA, while we found these antibodies in five patients out of the 35 studied (p=0.003). The clinical features of migraineurs with APA were similar to those of patients without them. After
C, Iñiguez +4 more
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Antiphospholipid Antibody Syndrome
Obstetrics and Gynecology Clinics of North America, 2014Antiphospholipid antibodies (aPLs) are acquired antibodies directed against negatively charged phospholipids. Obstetric antiphospholipid antibody syndrome (APS) is diagnosed in the presence of certain clinical features in conjunction with positive laboratory findings.
William H, Kutteh, Candace D, Hinote
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