Results 201 to 210 of about 513,078 (230)
Some of the next articles are maybe not open access.
Antiphospholipid antibody syndrome
Current Treatment Options in Neurology, 2000When the diagnosis of antiphospholipid antibody syndrome (aPS) is being considered in persons who have experienced an ischemic stroke or a transient ischemic attack, it is important to gauge how well the history and laboratory data fit with this diagnosis as opposed to other causes of infarct.
, Jacobs, , Levine
openaire +2 more sources
Antiphospholipid antibodies and stroke
Current Cardiology Reports, 2004Antiphospholipid antibodies are associated with venous and arterial thrombo-occlusive events, including stroke. They are a heterogeneous family of antibodies that react to negatively charged membrane-bound phospholipids or phospholipid-protein complexes.
openaire +2 more sources
Platelets and Antiphospholipid Antibodies
Lupus, 1996The involvement of platelets in the antiphospholipid syndrome is complex and the full pathogenic significance is not fully understood. The binding of aPL antibodies to the platelet membrane may result in the thrombopenia and further haemostatic activation.
openaire +2 more sources
JCR: Journal of Clinical Rheumatology, 1997
Although significant progress has been made during the last decade in our knowledge of the antiphospholipid antibodies (aPL), there are two major questions in clinical practice that require further guidelines: Indications for aPL determination and laboratory tests to choose. This article reviews the main clinical indications to search for aPL (systemic
R, Cervera, J, Font, R A, Asherson
openaire +2 more sources
Although significant progress has been made during the last decade in our knowledge of the antiphospholipid antibodies (aPL), there are two major questions in clinical practice that require further guidelines: Indications for aPL determination and laboratory tests to choose. This article reviews the main clinical indications to search for aPL (systemic
R, Cervera, J, Font, R A, Asherson
openaire +2 more sources
Antiphospholipid antibodies and malignancies
Autoimmunity Reviews, 2010Since the 1980s it is known that an important thrombogenic mechanism is mediated by antiphospholipid antibodies (aPL). Aim of this review is to discuss how much aPL presence may worsen the thrombophilic state of neoplastic patients and how much cancer may worsen and extend the thrombophilic state of patients with Antiphospholipid Syndrome (APS). In the
TINCANI, Angela +2 more
openaire +3 more sources
Antiphospholipid Antibodies in Children
Seminars in Thrombosis and Hemostasis, 1998Lupus anticoagulant (LA) is made up of heterogeneous IgG and IgM antibodies that prolong clotting times in vitro and is associated with an increased rate of both thrombosis and hemorrhage in vivo, although thrombosis is far more common. Many mechanisms of action have been explored, but none explains the coagulation abnormality of every sample tested ...
openaire +2 more sources
Antiphospholipid antibody and antiphospholipid antibody syndrome.
Current opinion in rheumatology, 1992Over the past year, many reports have been published on a variety of clinical manifestations related to antiphospholipid antibodies. The low prevalence of anticardiolipin antibodies with the rare occurrence of thrombosis and a low rate of fetal loss in studies in Malaysia and China showed a potential role for local factors.
openaire +1 more source
Antiphospholipid Antibody Syndromes
Rheumatic Disease Clinics of North America, 1989There is no doubt that in some individuals the presence of antibodies to negatively charged phospholipids currently measured as the lupus anticoagulant, a biologically false positive VDRL, and anticardiolipin antibodies is associated with certain clinical features, in particular, a predisposition to both arterial and venous thrombosis and, in women, to
openaire +2 more sources