Results 21 to 30 of about 21,621 (186)

Clinical, Laboratory, and Therapeutic Analyses of 21 Patients with Neonatal Thrombosis and Antiphospholipid Antibodies: A Literature Review

Journal of Immunology Research, 2014
Objectives. A review of the literature reports neonatal thrombosis and antiphospholipid antibodies cases through a retrospective study that focuses on the pathogenesis and main clinical and laboratory manifestations of this disease. Methods.
Marcus Vinicius da Costa Peixoto, Jozélio Freire de Carvalho, Carlos Ewerton Maia Rodrigues   +2 more
doaj   +1 more source

Antiphospholipid Antibody Syndrome

Archives of Pathology & Laboratory Medicine, 2011
Antiphospholipid antibodies are directed against phospholipid-protein complexes and include lupus anticoagulant, anticardiolipin antibodies, and anti–beta-2 glycoprotein I antibodies. Antiphospholipid antibody syndrome is a common cause of acquired thrombophilia and is characterized by venous or arterial thromboembolism or pregnancy morbidity and the ...
Nikhil A, Sangle, Kristi J, Smock
openaire   +2 more sources

Antiphospholipid Syndrome Associated with Systemic Lupus Erythematosus: A Case Report [PDF]

International Journal of Biomedicine
Antiphospholipid syndrome (APS) is an autoimmune disorder characterized by venous or arterial thrombosis and/or pregnancy outcomes in the presence of persistent antiphospholipid antibodies like lupus anticoagulant (LAC), anti-cardiolipin (aCL), and anti ...
Ina Toska, Ervin Rapushi, Rexhep Shkurti, Anila Mitre   +3 more
doaj   +1 more source

Prevalence of antiphospholipid antibodies in post-COVID and vaccinated individuals [PDF]

Infectious Diseases and Tropical Medicine
OBJECTIVE: The outbreak of COVID-19 resulted mainly in respiratory disease; however, apart from that, the infection was presented with random systemic thromboembolic events.
S. Al-Rustum, T. Kobulashvili, P. Sharma, S. Habeebulla, L. Bakhtadze   +4 more
doaj   +1 more source

Anticardiolipin Autoantibodies as Useful Biomarkers for the Prediction of Mortality in Septic Patients

Journal of Immunology Research, 2022
Background. The detection of antiphospholipid antibodies (aPL) is of interest because of their importance in the pathogenesis of arterial or venous thrombosis. They could be a “second hit” of an inflammatory event such as infection.
Amal Abouda, Z. Hajjej, A. Mansart, W. Kaabechi, D. Elhaj Mahmoud, O. Lamine, E. Ghazouani, M. Ferjani, I. Labbene   +8 more
doaj   +1 more source

Antiphospholipid Antibodies

Archives of Pathology & Laboratory Medicine, 2002
Abstract Objective.—To review the role of lupus anticoagulants in the pathogenesis of both venous and arterial thromboembolic events, as well as in recurrent spontaneous abortions. The pathophysiology of lupus anticoagulants and associated antiphospholipid antibodies (eg, anticardiolipin antibodies) is also discussed. Data
openaire   +3 more sources

Spinal Cord Infarction Versus Idiopathic Transverse Myelitis: Clinical, Radiological, and Functional Insights From a Retrospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji, Jianlong Zhang, Yiming Shi, Shiyu Shan, Yang Du, Guangshuo Li, Ying Jin, Yani Zhang, Chuanying Wang, Yijun Lin, Yuhao Guo, Decai Tian, Xingquan Zhao, Tian Song   +13 more
wiley   +1 more source

Antiphospholipid Antibodies and COVID‐19: A Systematic Review of Clinical Implications

Immunity, Inflammation and Disease
Introduction As the COVID‐19 pandemic transitions, understanding the intricate dynamics of the disease becomes paramount. This systematic review explores the role of antiphospholipid antibodies in COVID‐19, focusing on their potential clinical ...
Tahereh Sabaghian, Amir Behnam Kharazmi, Fatemeh Omidi, Bahareh Hajikhani, Shabnam Tehrani, Sayna Mardani, Amir Hashem Shahidi Bonjar, Rosella Centis, Lia D'Ambrosio, Giovanni Sotgiu, Fabio Angeli, Mohammad Javad Nasiri, Giovanni Battista Migliori   +12 more
doaj   +1 more source

Antiphospholipid Antibodies Are Major Risk Factors for Non-Thrombotic Cardiac Complications in Systemic Lupus Erythematosus

Biomedicines
In systemic lupus erythematosus (SLE), cardiovascular complications are among the leading causes of death. Cardiovascular risk in SLE is even higher in the presence of antiphospholipid antibodies or secondary antiphospholipid syndrome (APS).
Nikolett Nagy, Bernadett Bói, Gábor Papp, Edit Fiák, Eszter Gáspár-Kiss, Bianka Perge, Nikolett Farmasi, Tünde Tarr   +7 more
doaj   +1 more source

Hyperandrogenemia Induces Trophoblast Ferroptosis and Early Pregnancy Loss in Patients With PCOS via CMA‐Dependent FTH1 Degradation

Advanced Science, EarlyView.
In PCOS patients with hyperandrogenemia, decreased ferritin heavy chain 1 (FTH1) causes Fe2⁺ overload and ferroptosis in trophoblasts. Androgens induce FTH1 protein degradation via AR‐LAMP2A‐mediated chaperone‐mediated autophagy pathway, leading to placental development disruption and early pregnancy loss. Metformin mitigates androgen‐induced placental
Hanjing Zhou, Weijie Yang, Na Liu, Qing Liu, Jiamin Jin, Chenqiong Zhao, Xiaoying Jin, Miao Gui, Haiyan Zhu, Songying Zhang, Yinli Zhang   +10 more
wiley   +1 more source