Results 21 to 30 of about 1,686,484 (283)

Clinical significance of antibodies to the phosphatidylserine/prothrombin complex

Современная ревматология, 2022
Classical serological markers of antiphospholipid syndrome (APS) are antibodies to cardiolipin, antibodies to β2-glycoprotein 1, and lupus anticoagulant.
T. M. Reshetnyak, F. A. Cheldieva, M. V. Cherkasova, A. M. Lila   +3 more
doaj   +1 more source

Antiphospholipid antibodies in patients with COVID‐19: A relevant observation?

Journal of Thrombosis and Haemostasis, 2020
High incidence of thrombosis in COVID‐19 patients indicates a hypercoagulable state. Hence, exploring the involvement of antiphospholipid antibodies (aPL) in these patients is of interest.
K. Devreese, Eleni A Linskens, D. Benoit, H. Peperstraete   +3 more
semanticscholar   +1 more source

Seronegative antiphospholipid syndrome: refining the value of “non-criteria” antibodies for diagnosis and clinical management

Haematologica, 2020
Antiphospholipid syndrome (APS) is a systemic autoimmune disease characterized by arterial and venous thrombotic manifestations and/or pregnancy-related complications in patients with persistently high antiphospholipid antibodies (aPL), the most common ...
P. Pignatelli, E. Ettorre, D. Menichelli, A. Pani, F. Violi, D. Pastori   +5 more
semanticscholar   +1 more source

Patient-derived anti-β2GP1 antibodies recognize a peptide motif pattern and not a specific sequence of residues

Haematologica, 2017
Antiphospholipid antibody syndrome is an autoimmune disease characterized by the presence of so-called antiphospholipid antibodies and clinical manifestations such as recurrent thromboembolic or pregnancy complications.
Philippe de Moerloose, Céline Fickentscher, Françoise Boehlen, Jean-Marie Tiercy, Egbert K.O. Kruithof, Karim J. Brandt   +5 more
doaj   +1 more source

Increased heterogeneity of brain perfusion is an early marker of central nervous system involvement in antiphospholipid antibody carriers. [PDF]

PLoS ONE, 2017
The non-criteria neuropsychiatric manifestations of antiphospholipid syndrome include headache, dizziness, vertigo, seizure, depression and psychosis. There were still no objective methods qualified to detect the early central nervous system involvement ...
Ting-Syuan Lin, Pei-Ying Hsu, Chin-Hao Chang, Chi-Lun Ko, Yu-Min Kuo, Yen-Wen Wu, Ruoh-Fang Yen, Cheng-Han Wu, Ko-Jen Li, Yenh-Chen Hsein, Song-Chou Hsieh   +10 more
doaj   +1 more source

16th International Congress on Antiphospholipid Antibodies Task Force Report on Antiphospholipid Syndrome Treatment Trends

Lupus, 2020
Antiphospholipid syndrome (APS), an acquired autoimmune thrombophilia, is characterised by thrombosis and/or pregnancy morbidity in association with persistent antiphospholipid antibodies.
H. Cohen, M. Cuadrado, D. Erkan, A. Duarte-García, D. Isenberg, J. Knight, T. Ortel, Anisur Rahman, J. Salmon, Maria G. Tektonidou, David J. Williams, R. Willis, S. Woller, D. Andrade   +13 more
semanticscholar   +1 more source

Antiphospholipid Antibodies in Critically Ill Patients With COVID‐19

Arthritis & Rheumatology, 2020
Coagulopathy is one of the characteristics observed in critically ill patients with coronavirus disease 2019 (COVID‐19). Antiphospholipid antibodies (aPLs) contribute to coagulopathy, though their role in COVID‐19 remains unclear.
M. Xiao, Yan Zhang, Shulan Zhang, Xuzhen Qin, P. Xia, W. Cao, Wei Jiang, Huan Chen, X. Ding, Hua Zhao, Hongmin Zhang, Chun-yao Wang, J. Zhao, Xuefeng Sun, R. Tian, Wei Wu, Dong Wu, Jie Ma, Yu Chen, D. Zhang, Jing Xie, Xiaowei Yan, Xiang Zhou, Zheng-yin Liu, Jinglan Wang, B. Du, Yan Qin, Peng Gao, Minya Lu, X. Hou, Xian Wu, Huadong Zhu, Yingchun Xu, Wen Zhang, Taisheng Li, Fengchun Zhang, Yongqiang Zhao, Yongzhe Li, Shuyang Zhang   +38 more
semanticscholar   +1 more source

The Pathophysiology of The Antiphospholipid Syndrome: A Perspective From The Blood Coagulation System

Clinical and Applied Thrombosis/Hemostasis, 2022
The antiphospholipid syndrome (APS), a systemic autoimmune disease characterized by a hypercoagulability associated to vascular thrombosis and/or obstetric morbidity, is caused by the presence of antiphospholipid antibodies such as lupus anticoagulant ...
R Arreola-Diaz MSc, A Majluf-Cruz MD, PhD, LE Sanchez-Torres PhD, J Hernandez-Juarez PhD   +3 more
doaj   +1 more source

A role for uric acid and the nalp3 inflammasome in antiphospholipid antibody-induced IL-1β production by human first trimester trophoblast [PDF]

, 2013
Women with antiphospholipid syndrome (APS) are at risk of recurrent pregnancy loss and obstetrical disorders, such as preeclampsia and intrauterine growth restriction (IUGR).
Vikki M Abrahams, Kavathas, Paula B., Melissa J Mulla, Crina M Boeras, Mulla, Melissa J., Paula B Kavathas, Jan J Brosens, Brosens, Jan J., Boeras, Crina M., Larry W Chamley, Jane E Salmon, Abrahams, Vikki M., Salmon, Jane E., Chamley, Larry W.   +13 more
core   +1 more source

Coagulopathy of COVID‐19 and antiphospholipid antibodies

Journal of Thrombosis and Haemostasis, 2020
Recently in the Journal of Thrombosis and Haemostasis, Harzallah and colleagues report the results of antiphospholipid antibody testing in a series of 56 patients with confirmed or suspected SARS-CoV-2 infection.[1] Twenty-five patients were found to be ...
Nathan T Connell, E. Battinelli, J. Connors   +2 more
semanticscholar   +1 more source