Results 41 to 50 of about 18,604 (234)
xTrimoABFold: De novo Antibody Structure Prediction without MSA [PDF]
arXiv, 2022 In the field of antibody engineering, an essential task is to design a novel antibody whose paratopes bind to a specific antigen with correct epitopes. Understanding antibody structure and its paratope can facilitate a mechanistic understanding of its function.
arxiv
Antiphospholipid Antibodies in Stillbirth [PDF]
Obstetrics & Gynecology, 2013 To compare antiphospholipid antibodies in deliveries with and without stillbirth using a multicenter, population-based case-control study of stillbirths and live births.Maternal sera were assayed for immunoglobulin (Ig)G and IgM anticardiolipin and anti-β2-glycoprotein-I antibodies.
Marian Willinger +15 more
openaire +3 more sources
On Pre-trained Language Models for Antibody [PDF]
arXiv, 2023 Antibodies are vital proteins offering robust protection for the human body from pathogens. The development of general protein and antibody-specific pre-trained language models both facilitate antibody prediction tasks. However, there have been limited studies that comprehensively explore the representation capability of distinct pre-trained language ...
arxiv
Antiphospholipid antibodies and infections [PDF]
Annals of the Rheumatic Diseases, 2003 Many infections have been found to be associated with antiphospholipid antibodies (aPL), although a pathogenic role for these antibodies has not usually been obvious except in a few isolated cases. Two types of aPL have been referred to as "autoimmune" and "infectious" types. This distinction, however, has subsequently been found not to be absolute.
R Cervera, Ronald A. Asherson
openaire +3 more sources
Arthritis &Rheumatology, EarlyView.Objective Cardiovascular disease (CVD) is a leading cause of death in individuals with systemic lupus erythematosus (SLE). We assessed atherosclerotic plaque progression and incident cardiovascular events in patients with SLE over a 10‐year follow‐up.
Nikolaos Papazoglou +2 more
wiley +1 more source
BiomedicinesIn systemic lupus erythematosus (SLE), cardiovascular complications are among the leading causes of death. Cardiovascular risk in SLE is even higher in the presence of antiphospholipid antibodies or secondary antiphospholipid syndrome (APS).
Nikolett Nagy +7 more
doaj +1 more source
International Journal of Gynecology &Obstetrics, EarlyView.Abstract Objective To explore the correlation between antinuclear antibodies (ANAs) and pregnancy loss (PL), and to observe its impact on the pregnancy outcomes of in vitro fertilization/intracytoplasmic sperm injection‐embryo transfer (IVF/ICSI‐ET) in recurrent PL (RPL) patients. Methods In this retrospective study, patients first seen at the hospital
Manman Liu +8 more
wiley +1 more source
Anticoagulantes Lúpicos versus Anticorpos Antifosfolípidos.
Acta Médica Portuguesa, 1998 The antiphospholipid antibodies (aPL) present in "antiphospholipid-protein syndrome and autoimmune disorders" are associated with thromboembolic episodes, such as venous and/or arterial thrombosis and fetal loss. Patients with antiphospholipid antibodies
M I Pereira
doaj +1 more source
Predicting in vivo escape dynamics of HIV-1 from a broadly neutralizing antibody [PDF]
, 2020 Broadly neutralizing antibodies are promising candidates for treatment and prevention of HIV-1 infections. Such antibodies can temporarily suppress viral load in infected individuals; however, the virus often rebounds by escape mutants that have evolved resistance.
arxiv +1 more source
Revista Ciências em Saúde, 2019 Antiphospholipid syndrome (APS) was characterized as an autoimmune condition with the production of antiphospholipid antibodies (aPL) associated with thrombosis and morbidity in pregnancy.
Thaís da Silva Santos +4 more
doaj +1 more source